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cover of episode Rapid Response: How Cost Plus Drugs is revolutionizing pharma, with CEO Alex Oshmyansky

Rapid Response: How Cost Plus Drugs is revolutionizing pharma, with CEO Alex Oshmyansky

2024/12/3
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Masters of Scale

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Alex Oshmyansky
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Bob Safian
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Alex Oshmyansky 创立 Cost Plus Drugs 的初衷是为了解决药物价格过高的问题,他认为医药行业中存在一个由三个大型药品福利管理公司 (PBM) 组成的卡特尔,他们通过操纵药物价格获取巨额利润,导致患者负担过重。Cost Plus Drugs 通过绕过 PBM 系统,直接从药物制造商处采购药物,并以成本加 15 美元运费的价格销售,大幅降低了药物价格。他与 Mark Cuban 的合作也对公司的发展起到了至关重要的作用。 Cost Plus Drugs 的成功主要依靠口碑传播,几乎没有进行市场营销投入。起初,许多制药公司由于担心大型制药公司的压力而拒绝与 Cost Plus Drugs 合作,但随着 Cost Plus Drugs 的成功,越来越多的制药公司开始与其合作。Alex Oshmyansky 认为,降低药物价格不会影响制药公司的研发投入,反而由于透明化的价格体系,制药公司能够获得更多利润。他认为,政府的政策和法规难以有效解决药物价格问题,私营部门的改革更为重要。大型企业如果摆脱对大型 PBM 的依赖,将会促使医药行业进行自我改革。 Cost Plus Drugs 公司除了直接面向消费者销售药物外,还开始自主生产药物,专注于生产短缺药物,并计划将自动化生产技术小型化,以便在全球范围内快速应对药物短缺问题。Alex Oshmyansky 认为,他的成功很大程度上归功于他的耐心和毅力,他能够忍受繁琐的官僚程序,并坚持长期目标。他认为,Cost Plus Drugs 公司目前仍处于发展初期,还有很长的路要走,但公司正处于指数级增长阶段,并对医药行业产生了重大影响。 Bob Safian 作为主持人,主要对 Alex Oshmyansky 进行采访,并对 Cost Plus Drugs 的商业模式、发展历程以及对医药行业的影响进行总结和评价。他强调了 Cost Plus Drugs 公司成功地大幅降低了处方药的价格,这是几十年来公共政策都未能实现的。他还关注了 Cost Plus Drugs 公司的增长模式,以及 Alex Oshmyansky 如何平衡耐心和侵略性。Bob Safian 也提到了政府对药物价格的调查,以及 Alex Oshmyansky 对 PBM 公司的批评。

Deep Dive

Key Insights

Why did pharmaceutical companies initially hesitate to work with Cost Plus Drugs?

Pharmaceutical companies were pressured by a cartel of pharmacy benefit managers (PBMs) not to do business with Cost Plus Drugs, threatening to cut off their products from the PBMs' distribution channels.

How did Alex Oshmiansky initially connect with Mark Cuban?

Oshmiansky found Cuban's public Gmail address and sent him an email, which led to a quick response and subsequent investment from Cuban.

What was the key innovation of Cost Plus Drugs?

The company revealed the true cost of purchasing drugs and added a $15 shipping fee, aiming for transparency in pricing.

How does Cost Plus Drugs manage to sell drugs at such low prices?

By bypassing the traditional distribution chain controlled by PBMs, Cost Plus Drugs can purchase drugs directly from manufacturers at lower prices and pass on the savings to consumers.

What was the triggering event that led Alex Oshmiansky to focus on reducing drug prices?

The dramatic price increase of a drug by Martin Shkreli, known as the 'pharma bro,' which highlighted the exploitative practices in the pharmaceutical industry.

Why did Alex Oshmiansky decide to reincorporate Cost Plus Drugs as a for-profit company?

Advice from Y Combinator's Sam Altman suggested that raising funds as a nonprofit would be difficult, leading Oshmiansky to reincorporate as a public benefit corporation to attract investment.

What is the primary focus of Cost Plus Drugs' manufacturing operations?

The company focuses on producing drugs that are in shortage, often neglected by other manufacturers due to low profit margins.

How does Cost Plus Drugs use robotics in its manufacturing process?

The company employs robotic arms in hermetically sealed chambers that are sterilized by vaporized hydrogen peroxide, allowing for rapid and sterile production of medications.

Why does Alex Oshmiansky continue to practice radiology while running Cost Plus Drugs?

Practicing radiology provides him with discipline and decision-making skills, reinforcing the importance of taking responsibility and making timely decisions.

What is the current focus for Cost Plus Drugs in terms of partnerships?

The company is working on securing partnerships with major branded pharmaceutical companies like Johnson & Johnson, Bayer, and Pfizer to expand its product offerings.

Shownotes Transcript

With the help of co-founder Mark Cuban, Cost Plus Drugs CEO Alex Oshmyansky is radically re-engineering the pharma marketplace and dramatically cutting the price for many prescription drugs. Oshmyansky joins Rapid Response host Bob Safian to share his amazing journey — from struggling as an immigrant in primary school to starting college at age 13, how medical practice led to entrepreneurship, plus reimagining his original plan on advice from the legendary incubator Y Combinator. Oshmyansky explains how CostPlusDrugs stumbled into success, turning adversaries into allies and harnessing patience as a superpower.

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