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cover of episode Dinakar Singh - A Father’s Call To Action - [Invest Like the Best, EP.427]

Dinakar Singh - A Father’s Call To Action - [Invest Like the Best, EP.427]

2025/6/15
logo of podcast Invest Like the Best with Patrick O'Shaughnessy

Invest Like the Best with Patrick O'Shaughnessy
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Dinakar Singh: 我以我女儿的诊断为契机，毅然离开高盛，创立了Axon投资公司。Axon的名字来源于脊髓性肌萎缩症，这是一种会影响神经和肌肉的疾病，我的女儿就患有此病。我的目标是尽快取得投资上的成功，这样我就可以投入大量资金用于SMA的研究，以拯救我的女儿和其他患有这种疾病的孩子。在研究过程中，我发现人们对SMA的了解非常有限，这促使我与科学家和顾问合作，创建了一个虚拟公司，以加速药物的开发。我们采取并行处理的方法，同时进行多个研究方向，并与FDA和政治家建立了联系，以推动药物的批准。最终，我们成功开发了三种SMA药物，彻底改变了SMA的治疗前景。现在，如果新生儿在确诊后立即接受治疗，他们将不会出现任何症状。虽然我女儿的病情在药物出现之前一直在恶化，但她现在的生活非常成功和幸福。我们目前正在研究能够再生肌肉的药物，这些药物将帮助更多的人。我希望通过我的努力，能够为罕见病药物的开发带来更多的关注和资源，并为患者及其家庭带来希望。

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Dinakar Singh, founder and CEO of Axon, shares his inspiring story of transitioning from a successful career in finance to dedicating his life to finding a cure for his daughter's disease, spinal muscular atrophy (SMA). He explains the creation of his firm, TPG Axon, and the challenges faced in the biotech industry.
  • Dinakar Singh founded Axon, a family office succeeding TPG-Axon, a global long-short hedge fund.
  • His daughter's diagnosis with SMA prompted him to leave Goldman Sachs and dedicate his efforts to finding a cure.
  • He built a virtual company to accelerate drug development for SMA through parallel processing and collaboration with top scientists.

Shownotes Transcript

My guest today is Dinakar Singh). Dinakar is the founder and CEO of Axon, the family office successor to TPG-Axon, which was a successful global long-short hedge fund. We wanted to share his story on Father’s Day to honor the person and the dad that Dinakar is. He shares one of the most extraordinary stories at the intersection of finance and medicine I've ever encountered. This conversation explores the highest-stakes investment themes—timing, concentrated conviction, exceptional team building, and deploying resources toward outcomes that matter most. I will let him tell you his story. Please enjoy my conversation with Dinakar Singh. 

For the full show notes, transcript, and links to mentioned content, check out the episode page⁠⁠⁠ here.⁠⁠⁠)

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This episode is brought to you by⁠⁠⁠** Ridgeline**⁠⁠⁠). Ridgeline has built a complete, real-time, modern operating system for investment managers. It handles trading, portfolio management, compliance, customer reporting, and much more through an all-in-one real-time cloud platform. Head to⁠⁠⁠** ridgelineapps.com**⁠⁠⁠)** to learn more about the platform.**

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Editing and post-production work for this episode was provided by The Podcast Consultant (⁠⁠⁠https://thepodcastconsultant.com⁠⁠⁠)).

Show Notes:

(00:00:00) Welcome to Invest Like the Best

(00:06:17) The Diagnosis and Initial Reactions

(00:07:29) Understanding SMA and the Scientific Challenge

(00:09:15) The Drive to Fund Research and Find a Cure

(00:14:10) Building a Virtual Company for Drug Development

(00:19:02) Breakthroughs and the First Approved Drugs

(00:24:16) Personal Reflections and the Impact of the Journey

(00:40:25) Challenges in the Biotech Industry and Future Hopes

(00:46:43) The Kindest Thing Anyone Has Ever Done For Dinakar