In this podcast, researchers explore the link between gut health and fighting off MRSA infections.
They found that antibiotics disrupting gut bacteria made mice more susceptible to severe MRSA infections. However, fecal transplants from healthy mice improved infections drastically. The key molecule identified was spermidine, produced by gut bacteria. Mice with higher spermidine levels showed improved survival rates and reduced infection severity when infected with MRSA.
Spermidine seemed to boost the immune system's response to the infection. This research highlights the importance of gut health in combating antibiotic-resistant superbugs like MRSA.
Study:
https://pubs.acs.org/doi/epdf/10.1021/acsinfecdis.3c00669?ref=article_openPDF
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