276. The Future Of Supplements & Health Optimisation With Shawn Wells
Boost Your Biology with Lucas Aoun
Deep Dive
Why is it important to go with a reputable brand when buying supplements?
Reputable brands ensure their products meet label claims, are free from heavy metals and banned substances, and are third-party tested. Many low-tier contract manufacturers and unknown brands, especially on platforms like Amazon, use dry labbing—buying untested raw materials and printing fake lab tests—resulting in products that may contain no active ingredients or harmful substances.
Why is dihydroberberine considered a powerful supplement for metabolic health?
Dihydroberberine has been shown to lower blood glucose, decrease insulin, increase ketones, reduce inflammation, and improve lipid profiles. It also helps suppress advanced glycation end products and advanced lipid end products, which are precursors to metabolic diseases and aging. Additionally, it can elevate growth hormone, IGF-1, and sirtuin gene activation, all of which contribute to better metabolic health and longevity.
Why does blood sugar variability and high insulin affect overall health and aging?
High blood sugar and insulin levels can lead to metabolic dysfunction, insulin resistance, and inflammation, which are precursors to various diseases and accelerated aging. These conditions can also cause brain fog and cognitive decline, especially when chronic. By improving blood sugar and insulin levels with interventions like dihydroberberine, better health and longevity outcomes can be achieved.
Why has the focus in the supplement industry shifted from weight loss to metabolic health and longevity?
While weight loss supplements were popular in the past, the industry has evolved to focus more on metabolic health and longevity. This shift is partly due to the understanding that metabolic health is crucial for overall well-being and longevity. Additionally, popular pharmaceuticals and supplements that target metabolic pathways, such as GLP-1 agonists, have gained significant traction, influencing consumer interest in metabolic health.
Why is parazanthine a better alternative to caffeine for energy and focus?
Parazanthine, a metabolite of caffeine, provides sustained energy and focus without the side effects associated with caffeine, such as anxiety, agitation, and sleep disruption. It has a consistent 3.5-hour half-life, meaning it works the same way for every person without bioindividuality. Parazanthine also improves neurotransmitters like serotonin and dopamine, enhances brain-derived neurotrophic factor (BDNF), and reduces oxidative stress, making it a cleaner and more effective choice.
Why is the gut-brain axis important in health and longevity?
The gut-brain axis is crucial because the majority of neurotransmitters are produced in the gut. This axis affects cognitive function, mood, and overall health. Dysbiosis in the gut can lead to issues like depression and cognitive decline. Maintaining a healthy gut with probiotics and other supplements can improve brain function and support longevity.
- Shawn Wells' extensive experience in supplement research and development.
- The importance of human connection in the supplement industry.
- Challenges in bringing new ingredients to market.
- The need for greater legitimization of supplements.
Shownotes Transcript