278. Could This Be Bigger Than Tongkat Ali?
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The information provided in this podcast episode is for entertainment purposes and is not medical advice. If you have any questions about your health, contact a medical professional. This content is strictly the opinions of Lucas Owen and is for informational and entertainment purposes only. The references, claims and scientific information linked to any products

are only applicable to those listeners who are based in the US. If you are outside the US, this information does not apply to you. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult with their doctors or qualified health professionals regarding specific health questions.

Thank you for listening to the Boost Your Biology podcast. My name is Lucas Owen. I uncover the most cutting edge health information on the planet, ranging from hormones, nutrition, supplementation, fat loss, biohacking, longevity, wellness, and a whole lot more. Welcome to the Boost Your Biology podcast.

If you're a guy who's been looking to boost testosterone levels as high as possible naturally, then there's no doubt you've come across Tongkat Ali, otherwise known as Urucoma Longifolia. What I'm gonna do is actually share with you a herbal extract that I haven't seen explored at all in the health optimization space. And that is something called Lespedeza Cuneata or otherwise Lespedeza Cuneata. Now, I just wanna remind ourselves

why Tongkat Ali has become so famous and popular in the health optimization space. Now Tongkat Ali is also known as Uricoma Longifolia. It's a traditional Malaysian plant extract most known for its aphrodisiac and pro fertility effects while also having anti-pirotic, anti-malarial, antibiotic and anti-diabetic properties in rodents.

Now, it is commonly thought to stimulate testosterone levels, improve sexual desire and ability, and increase athletic ability, muscle strength, and muscle size. Now, if we take a look into how Tonka Ali actually works in the human body,

The currently proposed mechanism for increasing testosterone levels is traced to the uripeptide content. Now research has shown these uricoma peptides actually stimulate the release of free testosterone from sex hormone binding globulin, otherwise known as SHBG and improves hormonal profiles.

Now over a dozen rodent studies have found improved sex drive, balanced hormonal profile, so lower cortisol and higher testosterone and enhanced physical ability. Now human trials supplementing Tonkat Ali demonstrate

reductions in fatigue, heightened energy and mood, and a greater sense of wellbeing. Here's just a reminder why so many people love Tonka Dali. And it's because we see in dozens of anecdotal reports

that Tonka Ali literally leads to increased levels of free testosterone. And that is confirmed through blood work, blood testing, and most guys experience increased energy, libido, they note that their strength training has improved.

and they feel like they have reductions in fatigue. They might feel more alpha than usual. And they also say that tonkatali does appear to increase motivation to work out and mood. So I might actually quickly share with you my experience using tonkatali. Tonkatali is a herb that makes me very confident. Like,

That typical alpha male feeling, it gives me that dominance, social confidence. I can back myself. I feel like I'm confident in the bedroom. I feel extremely explosive in the gym. And just the way that pretty much every guy wants to feel is how I respond to Tonka Dalit.

Now, this new tonkatli is called Lespedeza cuneata. Now, al cuneata is a perennial herb with shrub properties that typically grows in lowland grasslands and fields. Now, it has been shown to nourish the liver and lungs as well as alleviate symptoms of male menopause. Now, al cuneata contains many active substances such as

pinnitol, flavonoids, phenol compounds and beta-cetosterol. In particular, the flavonoids quercetin, camphorol, vitexin and desmodin have been separately studied for their health benefits. Now research on aged rats given oral administration of this particular extract has shown alleviated andropause symptoms, increased testosterone levels, a decrease or reduction in body fat,

increase muscle mass, increase amount of semen and number of sperm, decrease serum lipids, a reduction in SHBG, just like what we see with Tonka-Dali, and also a reduction in PSA, prostate specific antigen. Increase gene expression of testosterone synthesis enzymes and decrease in aromatase and 5-alpha reductase without any significant side effects.

Now the reduction in 5-alpha reductase, I don't believe this is a very potent effect compared to other herbs, but the main uses for lespedeza, cuneata,

Researched treatment indications include prostatic hyperplasia, hormonal balance and testosterone deficiency syndrome, erectile dysfunction, improving age male symptoms, alleviation of andropause symptoms experienced by aging males, anti-carry properties for oral health, and also anti-inflammatory effects.

So let's look at how specifically lespedeza cuneata affects testosterone levels. So lespedeza cuneata increases free testosterone by decreasing SHBG, which is what we see with Tonka-Dali, which basically binds to testosterone. And additionally, it decreases 5-alpha reductase, which converts testosterone into DHT.

Now, I do believe that the effect is not so much in the blood and the brain. Remember, if we inhibit DHT production in those sort of areas of the body, that's usually where we see most amount of side effects. But what we see is that, you know, this Lespedeza cuneata has some pretty interesting research. Now,

Interestingly, gargling with a mouthwash containing lespedeza cuneata extract is actually useful in preventing dental caries and inhibiting its progression.

Now, it also appears that this particular extract can accelerate wound healing through anti-inflammatory activity and induction of collagen regeneration, as well as it reduces the scar area surrounding wounds. Now, accordingly, this particular extract could be useful as a cosmeceutical in the cosmetic industry. Now, of course, we're looking at how Lespedeza actually works. Now, obviously,

the pathways aren't that well established but it does appear that it lowers shbg inflammation and the expression of five off reductase and inflammation it further inhibits that pcna gene

And also it appears to improve sperm count and muscle mass in rats by increasing the levels of nitric oxide, nitric oxide synthase, CGMP, testosterone, and 17 beta hydroxy steroid dehydrogenases, as well as decreasing SHBG.

So if we were to look at hypothetical human equivalent dosages, we're looking at around 125 to 250 milligrams per kilogram per day in rats, which is equivalent to roughly 20 to 40 milligrams per kilogram per day in humans for about four weeks. For example, that would be around 1200 to 2400 milligrams per day for a 60 kilogram human.

"Experimentally in humans, 1250 milligrams "of this particular extract powder "split into two daily doses "was taken orally for eight weeks."

It basically shows us that this particular herb shows tremendous promise for increasing testosterone and improving symptoms of androgen deficiency in males. So if you are looking to optimize your testosterone, improve your sex drive and function and augment your exercise performance and muscle mass,

then this particular herb may be a solution over Tonkat Ali or perhaps even stacked together with Tonkat Ali. So this is phenomenal herbal research that I'm always excited to share with you guys. So that wraps up today's podcast. If you did find this episode helpful, please consider leaving a review. Thank you very much for tuning in. I look forward to seeing you in the next podcast.

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And guess what? Life insurance is probably a lot more affordable than you think. In fact, most people think life insurance is three times more expensive than it is. So with State Farm Life Insurance, you can protect your loved ones without breaking the bank. Not sure where to start? State Farm has over 19,000 local agents that can help you choose an option to fit your needs and budget. Get started today and contact a State Farm agent or go to statefarm.com. Hey guys,

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