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311. Testosterone & Hormone Optimisation With Hans Amato
2025/4/17
Boost Your Biology with Lucas Aoun
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Hans Amato
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Lucas Aoun
Lucas Aoun: 我专注于激素健康，特别是甲状腺功能、睾酮水平、饮食和新营养发现的潜力。我强调持续健康监测技术和天然补充剂在优化激素健康中的作用。我还探讨了咖啡因对激素的影响以及将各种水果纳入饮食以促进整体健康的好处。
我定期进行血液检测，监测促甲状腺激素（TSH）、甲状腺素（T4）和三碘甲状腺原氨酸（T3）等指标。我对硼能否提高T3水平感兴趣，并进行了一些研究。我还对C反应蛋白（CRP）等炎症指标的水平进行监测。我观察到，在高强度运动后，神经系统会完全崩溃，这可能与线粒体功能障碍、乳酸堆积和炎症有关。运动耐受性下降可能与肠道菌群变化、激素水平下降和营养缺乏有关。关于非那雄胺对线粒体和肠道健康的有害影响，存在一些研究证据。修复神经系统稳定性和运动耐受性应优先关注体内已有的物质，例如辅酶Q10、肌肽等。我正在实验使用覆盆子酮，观察其对IGF-1的影响。在使用补充剂时，应进行客观的检测和跟踪，而非仅仅依赖主观感受。我正在跟踪乳酸水平，以更好地了解身体对营养的需求。如果拥有连续睾酮监测器，我会研究其在一天中的变化规律、对压力的反应以及对不同补充剂的反应。睾酮是信号分子，有助于适应环境，不同类型的压力会产生不同的反应。睾酮增强剂的效果可能并非完全来自睾酮本身的提升，也可能与多巴胺等其他神经递质有关。在关注连续睾酮监测器数据的同时，也应关注自身感受、训练效果和性功能等方面。停用T3后，可能有助于降低反向T3的水平。反向T3的水平应结合其他指标综合考虑，并非总是需要过度关注。T3可以改善5α还原酶和5β还原酶的比例，从而影响DHT的代谢。我采用小剂量多次服用T3的方式，以模拟体内T3的自然分泌模式。过量服用T3可能导致肌肉分解。T3对食欲的影响因人而异。我从未见过T3水平极高的肥胖个体。优化甲状腺功能可以改善消化功能。如果拥有连续甲状腺监测器，我会研究睡眠剥夺、不同类型的训练以及各种药物和补充剂对其的影响。睾酮可能储存在睾丸的巩膜白膜中，睾丸按摩可能有助于释放睾酮。我研究了饮食胆固醇对睾酮水平的影响。我的过敏反应可能是限制睾酮提升的因素，而非胆固醇的生物利用度。突然停用睾酮可能导致肠道菌群变化，进而影响健康，例如视力模糊。恢复睾酮轴可以尝试多种方法，包括饮食调整、补充剂和特定食物。从动物研究中获得的营养信息应谨慎对待，需要考虑剂量和生物利用度等因素。各种食物的营养益处累积起来，对整体健康有益。个体对营养的需求差异很大，应选择适合自己的饮食方式。我对维生素A5及其对多巴胺的影响感兴趣。维生素A对睾酮、生育能力和多巴胺等方面有重要作用，但个体差异很大。大多数脂溶性维生素在一定程度上具有抗芳香化酶作用，从而促进睾酮分泌。不同形式的维生素具有不同的生物利用度和作用机制。我建议人们摄入各种水果，因为它们具有独特的健康益处。咖啡对人体激素的影响，特别是睾酮，尚需进一步研究。咖啡主要影响去甲肾上腺素等儿茶酚胺类物质，对皮质醇的影响相对较小。
Hans Amato: 我正在进行一项实验，通过补充剂来提高IGF-1水平，并观察其对其他激素和指标的影响。与生长激素相比，IGF-1具有更低的胰岛素抵抗风险，是促进肌肉生长的主要因素。生长激素通过刺激脂解作用，增加游离脂肪酸，从而干扰葡萄糖氧化，可能导致血糖升高。我定期进行全面的血液检测，以监测多种激素和健康指标。剧烈运动后神经系统崩溃可能与线粒体功能障碍、乳酸堆积和炎症有关。运动耐受性下降可能与肠道菌群变化、激素水平下降和营养缺乏有关。关于非那雄胺对线粒体和肠道健康的有害影响，存在一些研究证据。一项动物研究表明，非那雄胺停药后才出现肠道问题。修复神经系统稳定性和运动耐受性应优先关注体内已有的物质，例如辅酶Q10、肌肽等。我正在实验使用覆盆子酮，观察其对IGF-1的影响。在使用补充剂时，应进行客观的检测和跟踪，而非仅仅依赖主观感受。我正在跟踪乳酸水平，以更好地了解身体对营养的需求。如果拥有连续睾酮监测器，我会研究其在一天中的变化规律、对压力的反应以及对不同补充剂的反应。睾酮是信号分子，有助于适应环境，不同类型的压力会产生不同的反应。睾酮增强剂的效果可能并非完全来自睾酮本身的提升，也可能与多巴胺等其他神经递质有关。在关注连续睾酮监测器数据的同时，也应关注自身感受、训练效果和性功能等方面。突然停用睾酮可能导致肠道菌群变化，进而影响健康，例如视力模糊。恢复睾酮轴可以尝试多种方法，包括饮食调整、补充剂和特定食物。从动物研究中获得的营养信息应谨慎对待，需要考虑剂量和生物利用度等因素。各种食物的营养益处累积起来，对整体健康有益。个体对营养的需求差异很大，应选择适合自己的饮食方式。
supporting_evidences
Hans Amato: 'Just my regular ones. I did blood work yesterday, so I'm waiting for the results I'm going to get later after this call.'
Lucas Aoun: 'They're just ones that I like to keep an eye on.'
Hans Amato: 'So my standard list is growth hormone IGF-1, TSH, free T3, a lipogram, DHA sulfate, liver panel, complete blood count, free testosterone, which includes total SSBG, estradiol.'
Lucas Aoun: 'Personally, I've actually never seen my...'
Hans Amato: 'Yeah, so obviously, usually when that happens, they weren't like that before.'
Hans Amato: 'This was really interesting to me where while on finasteride, these animals didn't get any gut issues.'
Hans Amato: 'I like the ones that's already found in the body, right?'
Hans Amato: 'I can say like one of the things that I've started to experiment now, I forgot to take it this morning, is raspberry ketones.'
Hans Amato: 'So this is what like irks me a little bit online as people use supplements, like, yeah, I feel it.'
Hans Amato: 'So, which is really interesting because you check it fast and you check your response to food.'
Hans Amato: 'It's like if you can do a testosterone, like a CGM thing, I think that would be freaking amazing.'
Hans Amato: 'So this is why black people tend to have higher levels of testosterone.'
Lucas Aoun: 'They say that they feel great.'
Lucas Aoun: 'Because, um, Like, for example, I've injected testosterone before, like high doses.'
Lucas Aoun: 'T3 administration, so like using T3, I wasn't aware of this, but even after stopping can actually help to like bump out the reverse T3 or something like that.'
Hans Amato: 'Well, wherever, because like the body is like, so think about it this way. Everyone is obsessing about reverse T3, but you don't, it's not always necessary to obsess about it.'
Hans Amato: 'The most powerful thing that improves the 5-alpha to 5-beta ratio is T3.'
Hans Amato: 'yeah so your thyroid is producing a boatload of t4 and then your body is converting it in the tissue on demand'
Hans Amato: 'So if you're spiking yourself with an excessive amounts, like T3 is catabolic.'
Hans Amato: 'But I think it can go both ways.'
Hans Amato: 'No, no. A base is going to be normal.'
Hans Amato: 'But what if you just optimize your thyroid?'
Lucas Aoun: 'Oh, geez. I would definitely love to see the impact of sleep deprivation.'
Hans Amato: 'And that's why testicular massage, like massaging the testes can actually release more testosterone into the bloodstream.'
Lucas Aoun: 'I mean, saturated fat, I understand that. Eggs, maybe what would happen if you ate a lot of cholesterol?'
Hans Amato: 'So it would have maybe been interesting if I were to use enclomophene before, see what my test is, and then use the eggs on top of that to see if I get an additional boost from that.'
Hans Amato: 'And we know how important hormones is for including colon health and your hormones and your urgence matters shape the microbiome.'
Hans Amato: 'I last year was all about like increasing my allege.'
Hans Amato: 'Like when they, let's say you look at the garlic and onion studies for animals, right?'
Hans Amato: 'But in saying that, like when I, so like I'll still eat onion, right?'
Hans Amato: 'So it's really just up to the individual.'
Lucas Aoun: 'One thing that I've come across recently, I don't know if you've ever seen it in your own research, is a new vitamin called vitamin A5.'
Hans Amato: 'But then you have guys like Grant, the antivitamin, is it Grant?'
Hans Amato: 'Yeah, I would say so.'
Hans Amato: 'Like let's have vitamin B3, right?'
Lucas Aoun: 'I... When you research fruit, you realize all of them has unique benefits.'
Hans Amato: 'That's a good question. I know when people come off of coffee and then they drink coffee, the first four weeks they get a good spike in tea, but then the next four weeks it just goes back to normal.'
Hans Amato: 'But you're still going to get that increase in metabolic rate.'
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