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cover of episode 314. Top Supplement Mistakes, Science & Research With Dr Tyler Panzner

314. Top Supplement Mistakes, Science & Research With Dr Tyler Panzner

2025/5/5
logo of podcast Boost Your Biology with Lucas Aoun

Boost Your Biology with Lucas Aoun

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Dr. Tyler Panzner: 我从小就对补充剂很感兴趣,并在大学时期就开始自己制作和销售运动前补充剂。我的博士研究涵盖神经药理学、神经退行性疾病和癌症研究等领域。我对基因学的兴趣始于23andMe基因检测,通过研究自身基因突变(例如MAO和COMT基因)并调整补充剂方案,我改善了自己的健康状况。随后,我开始为朋友和家人提供基因检测和个性化健康建议,最终发展成为一项职业。在过去的两年半里,我已帮助超过700人改善健康状况,并相信个性化医疗是未来的发展方向。 我利用SelfDecode平台进行基因检测,该平台采用多基因风险评分技术,评估多个基因的多种突变,从而更准确地评估个体对营养物质的需求。许多基因检测公司只检测少数几个基因突变,这可能导致对个体需求的错误评估。例如,MTHFR基因突变并非决定补充剂剂量的唯一因素,需要考虑其他基因突变以及个体对营养物质的反应。 许多补充剂的剂量过高,例如甲基叶酸的剂量通常过高,应根据个体情况调整剂量。对于MTHFR基因突变者,叶酸的甲基化形式(甲基叶酸)并非总是最佳选择,叶酸的非甲基化形式(亚叶酸)可能更有效。甲基化参与神经递质的合成和分解,以及谷胱甘肽的产生,但过量甲基化可能导致过度兴奋。肝脏富含甲基B12和硫,过量摄入肝脏可能导致甲基化过度、亚硫酸盐超载和铜的问题。 常见的补充剂错误包括服用过量补充剂导致过度兴奋,以及服用多种单胺氧化酶抑制剂或儿茶酚-O-甲基转移酶抑制剂。补充剂研究通常只关注单一变量,而忽略了多种补充剂之间的相互作用,例如姜黄素可能导致贫血。不同形式的姜黄素对人体的影响不同,某些形式可能导致过度兴奋。 奥罗酸锂对我的焦虑和压力有显著的改善作用,让我感觉更平静和专注。奥罗酸锂通过加速单胺氧化酶和儿茶酚-O-甲基转移酶的活性来降低肾上腺素水平,从而改善焦虑和压力。肌酸是相对安全的补充剂,对大多数人来说益处大于风险,但少数人可能出现睡眠问题或胃肠道不适。GAA(氨基乙酰谷氨酸)是一种氨基酸衍生物,可以促进体内肌酸的合成,并可能改善肌酸的吸收和利用。精氨酸转化为阿格马汀的基因突变会影响个体对阿格马汀的反应,阿格马汀可以促进一氧化氮的合成。 从绿茶中提取的茶氨酸可以被认为是一种药物,因为任何改变生理机能的物质都可以被认为是药物。我希望看到更多关于基因及其对补充剂反应影响的研究,特别是关于多个基因突变的综合影响的研究。 Lucas Aoun: (访谈内容主要围绕Dr. Tyler Panzner的观点展开,没有提出独立的论点。)

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In this episode of the Boost Your Biology podcast, Lucas Aoun interviews Dr. Tyler Panzner, a specialist in supplements and genetics. They discuss Dr. Panzner's journey into the world of supplements, the evolution of genetic testing, and the importance of understanding methylation and its impact on health. The conversation also covers common mistakes people make with supplements, the role of glutathione, and the benefits of lithium orotate. In this conversation, Dr. Tyler Panzner and Lucas Aoun delve into the complexities of brain chemistry, the role of lithium in mental health, and the benefits of creatine as a supplement. They discuss the importance of understanding individual responses to supplements, the interactions between various compounds, and the need for more genetic research in health optimization. The dialogue emphasizes a holistic approach to health, considering both natural and synthetic substances as pharmacological tools.

Relevant links:

Cell Signaling Model of Disease Course: Begin to learn how Dr. Tyler Panzner views health, one pathway at a time. This free course shows an entirely new way of viewing your external world, whether it be foods, supplements, or lifestyle habits. Once you see life like this, you can NOT unsee it!

https://drtylerpanzner.com/cell-signaling

1:1 Deep Dive Genetic Analysis: Pinpoint precisely which foods, vitamins, supplements, and lifestyle habits your cells do (and don't) need to feel their best with a personal analysis and consult with Dr. Panzner.

https://drtylerpanzner.com/startyourjourney

Email Newsletter: Subscribe to Dr. Panzner's free email newsletter for weekly emails about cellular health, supplement science, and other quirky science to enhance your human experience of life.

https://drtylerpanzner.com/email-newsletter

Get Lucas’ New Supplement Here: https://www.inb4supps.com/

Chapters:

00:00 Introduction to the Podcast and Guest

02:53 Dr. Tyler Panzner's Journey into Supplements and Genetics

06:09 The Evolution of Genetic Testing and Its Implications

08:55 Understanding Methylation and Its Impact on Health

12:11 The Role of Glutathione and Sulfur in Health

14:59 Common Supplement Mistakes and Overstimulation

17:49 The Benefits and Risks of Lithium Orotate

30:56 Understanding Brain Chemistry and Anxiety

36:05 The Role of Lithium in Mental Health

41:02 Exploring Creatine and Its Benefits

49:00 Navigating Supplement Interactions

57:01 The Importance of Genetic Research in Health

Disclaimer:

The information provided in this podcast episode is for entertainment purposes and is NOT MEDICAL ADVICE. If you have any questions about your health, contact a medical professional. This content is strictly the opinions of Lucas Aoun and is for informational and entertainment purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult with their doctors or qualified health professionals regarding specific health questions. Neither Lucas Aoun nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this content. All consumers of this content especially taking prescription or over-the-counter medications should consult their physician before beginning any nutritional, supplement or lifestyle program. Hosted on Acast. See acast.com/privacy) for more information.