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cover of episode Bovine Neuropathology (HEADBUTTING) with Nicole Ackermans

Bovine Neuropathology (HEADBUTTING) with Nicole Ackermans

2022/1/13
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Ologies with Alie Ward

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Allie Ward
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Nicole Ackermans
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Nicole Ackermans: 本研究结合功能形态学和神经科学,通过分析死亡动物(大角羊和麝牛)的脑组织样本,研究头部碰撞行为造成的脑损伤。研究方法包括MRI扫描和免疫组织化学染色,结果显示存在死亡神经元和聚集的树突,证实了头部碰撞导致的脑损伤。此外,研究还探讨了头部碰撞行为的进化原因,认为这可能与繁殖竞争有关,即使这种行为可能导致脑损伤,但由于动物寿命较短且行为相对简单,脑损伤的影响可能有限。研究还涉及到对其他动物(如鲸类和野猪)头部碰撞行为的讨论,以及对现有防脑震荡设备设计的质疑。 Allie Ward: 访谈围绕着Nicole Ackermans博士关于动物头部碰撞行为的研究展开,涵盖了研究方法、发现、以及对相关现象的解释。访谈中讨论了脑震荡诊断的困难,以及将动物研究结果应用于人类的挑战。此外,访谈还涉及到学术界资金申请的困难,以及对一些基于动物模型的防脑震荡设备设计中存在的科学依据不足问题的讨论。 Nicole Ackermans: 我的研究关注的是动物,特别是大角羊和麝牛,它们经常发生头部碰撞。通过分析它们的脑组织样本,我们发现头部碰撞确实会导致神经元的损伤和死亡,这与人类的创伤性脑损伤非常相似。然而,我们也发现这些动物的脑部结构和生理机制可能具有某种程度的保护作用,使它们能够承受一定程度的脑损伤而不会产生严重的后果。此外,我们还探讨了这些动物头部碰撞行为的进化意义,以及这种行为与繁殖竞争之间的关系。我们发现,头部碰撞行为可能是一种为了争夺配偶而进化出的策略,即使这种行为可能导致脑损伤,但它带来的繁殖优势可能超过了脑损伤带来的风险。 Allie Ward: 访谈中,我与Nicole Ackermans博士讨论了她的研究成果,并就一些相关问题进行了深入探讨。例如,我们讨论了在野生动物中诊断脑震荡的困难,以及如何将动物研究结果应用于人类医学。我们还讨论了学术界资金申请的困难,以及一些基于动物模型的防脑震荡设备设计中存在的科学依据不足的问题。此外,我们还探讨了头部碰撞行为在不同动物物种中的普遍性,以及这种行为背后的进化机制。

Deep Dive

Key Insights

Why do animals like bighorn sheep and musk oxen engage in headbutting behavior?

Animals like bighorn sheep and musk oxen headbutt to compete for females and demonstrate their genetic superiority. Despite the potential for brain trauma, this behavior is a part of their reproductive strategy, and the males with the best genetics are more likely to survive and reproduce.

What did Dr. Nicole Ackermans find when she examined the brains of headbutting animals?

Dr. Ackermans found dead neurons and clumped dendrites in the brains of headbutting animals like musk oxen. These findings indicate brain trauma, with groups of neurofibrillary tangles at the bottoms of brain folds, suggesting traumatic injury.

How do bighorn sheep and musk oxen survive headbutting without severe brain damage?

Bighorn sheep and musk oxen have evolved thick skulls and horns that help protect their brains. While they do experience brain trauma, their protective structures allow them to survive long enough to reproduce, even if they might develop issues later in life.

What other animals besides ruminants engage in headbutting behavior?

Other animals that engage in headbutting include whales, dolphins, orcas, and even some birds like hornbills. These behaviors are often related to competition for mates or territory.

Why is it difficult to study the effects of headbutting on animals like bighorn sheep?

Studying the effects of headbutting in animals is challenging because there is no established behavioral scale for most species. Additionally, obtaining samples and funding for research is difficult, as there is not a significant financial gain associated with this area of study.

What is the controversy surrounding the Q collar and its use in sports?

The Q collar is a device designed to increase arterial pressure in the head, similar to that of bighorn sheep, to reduce the risk of concussions. However, it is based on a faulty premise and could be dangerous. The actual science behind it is not well-supported, and it has gained traction without proper scrutiny.

Why is it important to study headbutting in animals for human applications?

Studying headbutting in animals can provide insights into the mechanisms of traumatic brain injury and help develop better protective measures for humans. Understanding how animals like bighorn sheep survive headbutting can inspire new approaches to preventing and treating brain injuries in humans.

Shownotes Transcript

Slamming heads together to impress someone: why does this happen? Let’s ask Dr. Nicole Ackermans, whose current job involves receiving sheep heads and painstakingly counting damaged neurons from headbutting concussions. The Neuropathology episode last week gives all the concussion basics, but this one turns the microscope away from accidents and points it right at intentional behaviors in nature, from bighorn sheep to musk oxen, goats, woodpeckers, and some other animals that will freak you out. Also: questionable helmet ideas and horny hogs.

Get all the background on head trauma, including my recent brainwhack concussion)

Check Dr. Nicole Ackerman's website) and Twitter)

A donation was made to Society for Women's Health Research)

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Sound editing by Jarrett Sleeper) of MindJam Media)

Transcripts by Emily White of The Wordary)

Website by Kelly R. Dwyer)

Theme song by Nick Thorburn