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cover of episode How Antidepressants Work

How Antidepressants Work

2025/3/13
logo of podcast Stuff You Should Know

Stuff You Should Know

AI Chapters Transcript
Chapters
This chapter provides an introduction to depression, its prevalence, and symptoms. It also touches on historical treatments and the importance of seeking help.
  • Depression affects about 60 million adults in America.
  • Major depressive disorder is also known as clinical or unipolar depression.
  • The World Health Organization predicts depression will be the leading disease by 2030.
  • Symptoms include sadness, disrupted sleep, feelings of worthlessness, and lack of pleasure.
  • Depression is chronic or recurring for most people.
  • Historically, treatments included enemas, baths, positive thinking, diet, and exercise.

Shownotes Transcript

The good news is that we know antidepressants can treat major depression, helping millions of people live healthier lives. The bad news is that we don’t really know how they do that. Check out the theories on how antidepressants work in this episode.  

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