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cover of episode Is Aging a Disease? Epigenetics with David Sinclair

Is Aging a Disease? Epigenetics with David Sinclair

2024/3/22
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Chuck Nice
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David Sinclair
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Neil deGrasse Tyson
以主持《宇宙:时空之旅》和《星谈》等科学节目而闻名的美国天体物理学家和科学传播者。
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David Sinclair: 本文详细阐述了衰老的表观遗传学机制,认为衰老是一种疾病,可以通过重置细胞的‘软件’(表观基因组)来逆转。他介绍了信息理论衰老,并用小鼠实验举例说明了如何通过破坏和修复细胞的‘软件’来实现衰老的逆转。他还讨论了表观遗传的遗传性,以及生活方式对基因表达的影响,并指出可以通过改变生活方式来延缓衰老。此外,他还介绍了他们团队在逆转衰老方面取得的进展,例如治愈小鼠的失明,并展望了未来通过药物或基因疗法逆转衰老的可能性。 Neil deGrasse Tyson: 尼尔·德格拉斯·泰森主要从社会和历史的角度探讨了衰老问题,指出由于卫生条件的改善,人类寿命延长,但这并非衰老本身改变的结果。他还对David Sinclair提出的理论和实验结果表示了好奇和质疑,并提出了关于衰老的若干问题。 Chuck Nice: Chuck Nice主要负责提出一些与衰老相关的通俗易懂的问题,以帮助观众理解David Sinclair的观点。他关注的是衰老的实际应用以及对人类生活的影响。 Gary O'Reilly: Gary O'Reilly主要负责引导话题,并对David Sinclair的观点进行补充说明。

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Is aging a disease that can be cured? Neil deGrasse Tyson and cohosts Chuck Nice and Gary O’Reilly discover the field of epigenetics, the Information Theory of Aging, and curing blindness for mice with Professor of Genetics at Harvard Medical School, David Sinclair.

NOTE: StarTalk+ Patrons can listen to this entire episode commercial-free here: https://startalkmedia.com/show/is-aging-a-disease-epigenetics-with-david-sinclair/)

Thanks to our Patrons Jason L, Daniel Holzmann, Anne P Vance, Unknown, Myles G Blanton, Paul A. Straus, and Gregory Dees for supporting us this week.