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James McKillop
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Maren Kogan
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Maren Kogan: 2022年,美国每日吸食大麻的人数首次超过每日饮酒的人数,这是一个巨大的现象,约有1770万美国人每天或几乎每天吸食大麻。 美国人正在进行一项关于大麻使用对自身健康影响的实时实验,其结果和长期影响尚不明确。 与普遍认知相反,大麻具有成瘾性,可能导致对其他物质的依赖,并可能引发大麻使用障碍。 大量使用大麻可能导致大麻素呕吐综合征(CHS),这是一种严重的疾病,会导致剧烈呕吐和其他症状。 大量吸食大麻与中风、心血管疾病等风险增加有关,对青少年大脑发育的影响尤其令人担忧。研究表明,青少年大量吸食大麻可能增加抑郁症、自杀意念、精神分裂症和其他精神疾病的风险,并可能导致大脑发育紊乱。 美国联邦政府对大麻的管制滞后于市场发展,各州的法律法规不一致,导致大麻安全性和质量难以监管。大麻在美国的合法化程度参差不齐,联邦层面仍将其列为一级毒品,这阻碍了对其安全性和医疗用途的研究。 一些人认为大麻合法化是错误的,因为它带来了健康问题,并没有如预期那样改善刑事司法系统中的种族差距,并造成了新的公共卫生问题。 虽然大麻对许多人来说可能是无害甚至有益的,但它并非对所有人都是完全安全无害的,消费者需要谨慎,在政府制定公共卫生应对措施之前,消费者需要自己注意健康。 James McKillop: 加拿大全面合法化大麻的目的是为了实施公共卫生战略,减少危害,最大限度地发挥益处,主要目标是减少青少年接触大麻、为成年人提供合法途径获取大麻以及减轻刑事司法系统的负担。 加拿大合法化大麻六年后,青少年吸食大麻的情况没有显著增加,刑事司法系统的负担也减轻了,但成年人的大麻使用率却创历史新高,加拿大的大麻使用率处于历史最高水平,尤其是在20多岁的年轻人中。 虽然经济市场蓬勃发展,但大麻使用率过高、商店数量过多以及对医疗保健系统的负担等问题也令人担忧。急诊室和紧急护理中心就诊人数、大麻素呕吐综合征病例、孕妇寻求大麻相关护理以及酒驾检测呈阳性的大麻比例都有所增加。 虽然大麻的健康风险可能比酒精低,但尚不清楚大麻使用量的增加是否抵消了酒精带来的危害。加拿大的酒精零售额在合法化前后变化不大,而合法大麻的销售额却急剧增加,这表明大麻合法化对减少酒精危害的益处可能有限。 加拿大大麻经济既有繁荣也有萧条,许多生产商的股票在合法化后价值下跌,许多大麻店开张后又倒闭。大麻店数量过多,即使禁止广告,也构成了一种变相广告,对青少年和试图戒除大麻的人来说都是挑战。 魁北克省的大麻管制模式是加拿大最好的,因为它提高了购买年龄、禁止类似糖果的可食用大麻产品、实行省级垄断并严格控制商店数量。魁北克省的大麻管制模式更为严格,它提高了购买年龄,禁止类似糖果的可食用大麻产品,并实行省级垄断,这有助于减少大麻相关的危害。 建议经常吸食大麻的人尝试一个月不吸食大麻,以此评估自己是否有大麻使用问题。

Deep Dive

Key Insights

What is the current trend in marijuana use compared to alcohol in the United States?

For the first time in 2022, more Americans reported using marijuana daily or nearly daily than consuming alcohol at the same rate. Approximately 17.7 million Americans, or 5% of the population, use marijuana daily or near daily.

What are the potential health risks associated with daily marijuana use?

Daily marijuana use can lead to cannabis use disorder, with up to 18 million Americans potentially affected. It is also associated with cannabinoid hyperemesis syndrome, which causes severe nausea and vomiting, and increased risks of stroke, cardiovascular disease, and mental health issues like depression and suicidal ideation, particularly in teens.

What is cannabinoid hyperemesis syndrome (CHS) and how does it affect users?

Cannabinoid hyperemesis syndrome (CHS) is a condition affecting heavy, long-term marijuana users, causing severe cycles of nausea, vomiting, and stomach pain. Some sufferers find temporary relief only through hot showers, which has led to cases of burns from excessive heat exposure.

How has marijuana legalization impacted youth access and criminal justice in Canada?

In Canada, marijuana legalization aimed to reduce youth access, create a legal framework for adult use, and lessen the burden on the criminal justice system. While youth consumption has not sharply increased, arrests for cannabis have significantly decreased, and a large legal cannabis market has emerged.

What are the economic and public health outcomes of marijuana legalization in Canada?

Canada's legalization has led to a booming cannabis economy, displacing the illegal market. However, it has also resulted in increased emergency room visits for conditions like CHS, higher rates of cannabis use among pregnant women, and more impaired driving incidents involving cannabis.

How does Quebec's approach to marijuana legalization differ from other Canadian provinces?

Quebec has implemented stricter public health measures, including a higher legal age for access (21), banning edibles that resemble candy, and maintaining a provincial monopoly on cannabis sales. These measures have resulted in fewer observed harms compared to other provinces.

What advice does Dr. James McKillop offer to frequent marijuana users?

Dr. James McKillop recommends that frequent marijuana users consider taking a month off, similar to 'dry January,' to assess their relationship with cannabis. This break can help identify potential dependency and provide mental and physical health benefits.

Chapters
More Americans are using marijuana daily than alcohol, with an estimated 17.7 million daily or near-daily users. The reasons behind this are unclear, with factors like potency and frequency of use being unknown. This creates a large-scale, real-time experiment on the American public's health.
  • Daily marijuana use surpasses daily alcohol consumption in the US.
  • 17.7 million Americans report daily or near-daily marijuana use.
  • The potency and frequency of marijuana use are largely unknown.
  • The long-term health consequences of widespread marijuana use are unclear.

Shownotes Transcript

Translations:
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It's a new year. Maybe you're taking a month off from drinking, you know, dry January, and maybe you're replacing it with something else. Puff, puff, puff.

Some like one in five people who do dry January say they're smoking weed instead. And more Americans are now smoking weed daily than drinking daily. Current president is into it. No one should be in jail merely for using or possessing marijuana. Period. Future president is into it. I've had friends and I've had others and doctors telling me that it's been absolutely amazing, the medical experience.

Marijuana. Failed president and former prosecutor was down to clown. People shouldn't have to go to jail for smoking weed. Even health conscious brain worm guy likes it. My position on marijuana is that it should be federally legalized. Everyone's getting down with pot, but legislatively, we're still stuck with a hot mess in the United States. We're going to see what we can do about that on Today Explained.

This isn't your grandpa's finance podcast. It's Vivian Tu, your rich BFF and host of the Net Worth and Chill podcast. This is money talk that's actually fun, actually relatable, and will actually make you money. I'm breaking down investments, side hustles, and wealth strategies. No boring spreadsheets, just real talk that'll have you leveling up your financial game. With amazing guests like Glenda Baker... There's never been any house that I've sold in the last 32 years. You

It's not worth more today than it was the day that I sold it. This is a money podcast that you'll actually want to listen to. Follow Net Worth and Chill wherever you listen to podcasts. Your bank account will thank you later. At Criminal, we've made it a tradition every December to dedicate an episode entirely to animals who are really going for it.

You're listening to Today Explained.

Maren Kogan, senior correspondent at Vox. What's up with weed right now? So researchers found in 2022, for the first time, more Americans were using marijuana every day or nearly every day than consuming alcohol at the same rate. More Americans are doing daily weed than daily booze.

Yeah, it's a huge phenomenon. And if you think about it, the numbers are something like 17.7 million Americans say that they're getting a little high or smoking a little weed daily or near daily. That's not nothing. That's like 5% of the American public. So I smoke marijuana sometimes a lot every day. And I'll tell you, I smoke weed all day. So I would, yeah, I would imagine it would be worse if I didn't. How much do you smoke a day?

Probably an ounce, like a cool kid. We burning the cool ounce. This is all based on survey data. It's self-reported use. So are these people taking a little hit of a vape pen before they go to bed to deal with insomnia? BRB, about to escape and enter my magical fantasy world. It just calms me down. I'm able to sleep comfortably.

And I stay asleep. It's much easier and much more pleasant, the whole experience, because when you do sleep, you sleep like a log. I sleep really well. Are they people who wake and bake? You thinking what I'm thinking? Wake and bake. Let's go. Good morning to all the wake and bakers. It's time to wake and bake.

Are they people who are basically getting a little high before they go to class, before they go to their jobs? Getting lit before work, guys. Cheers. It's called self-care. Look it up. So I'm on my way to school and I gotta smoke. I gotta smoke before school.

We don't know how many times a day those people are using. We also don't know the potency of what they're using. So there's a huge range and variation. What we do know is that the market right now for marijuana and the number of sales are really going towards customers who are using very heavily. So we're talking multiple times a day. What we don't know exactly is what that means for personal or for public health. So essentially, Americans are conducting this real-time experiment on their own bodies.

Are people getting addicted to weed? Can you get addicted to weed? Yeah, so contrary to popular belief, it can be habit-forming for some people. It can increase risk of dependence on other substances. And a recent analysis by Columbia University researchers found that as many as 18 million people in the U.S. might have some form of cannabis use disorder, in other words, addiction. So it's simply not true that it's completely harmless for everyone.

Tell me more. What do we know about the harms, especially as we undergo this massive nationwide experiment and see more people smoking weed every day?

So one really good example of this is cannabinoid hyperemesis syndrome. Cannabinoid hyperemesis syndrome. It's a really fancy term for people who have used a lot of marijuana, heavy amounts over a long period of time, who begin throwing up really violently and are sort of unable to stop these cycles of nausea and vomiting. Huh.

Doctors and hospitals across the country are seeing people come in with cannabinoid hypermesis syndrome, and it can be really, really bad. Crazy stomach pains and migraines and nausea and diarrhea and all this other stuff. I was losing weight.

I was getting nauseous. I wasn't throwing up, but I was getting the joint pain. I really couldn't work out anymore without massive amounts of discomfort. If you're having crazy vomiting and nausea episodes and you smoke weed and nothing helps you except for laying in a very hot shower...

You likely have CHS. I'm not a doctor, I'm saying likely. You likely have CHS. There have been all sorts of horror stories of people who have burned themselves because one of the few things that makes people with this syndrome feel better is heat, so they'll take hot baths repeatedly. And yeah, people have actually burned themselves trying to get relief from the nausea they feel because they've been smoking so much weed.

Is cannabinoid hypermesis syndrome the only negative health impact we're seeing amongst people who are smoking more weed? No. So high levels of consumption is being associated with higher risk of stroke, cardiovascular disease. But the real issue here, and I think the real concern that a number of researchers have, is what regular marijuana use is doing to teens. Hmm.

There is particular concern about what regular heavy marijuana use does to adolescent and teen brains. So there have been studies that have shown an increased likelihood of depression and suicidal ideation associated with heavy marijuana use. In a few cases, it has been associated with the development of

schizophrenia and other psychotic disorders among young people. Studies have also shown disruptions in the anatomy of a developing brain. And teens often have, and honestly adult consumers too, often have really no idea what they're consuming and how safe it is. A big issue is a lot of people don't know dosing. So they tend to overconsume and then they have a very bad experience. Last time that I caught myself taking an edible, I legit

quote the ambulance because I thought I was having a heart attack. Once those edibles kicked in, my whole entire soul left my body and I'm not being dramatic. I literally disassociated. I was talking to the refrigerator, bawling my eyes out, throwing... Why don't we know more about what we're consuming and how safe it is? A lot of

Yeah.

For the consumers, it's confusing for the researchers, too. The regulations basically have not caught up to where the market is evolving. Poor K, no. One of the big reasons is that the federal government has basically allowed the states to...

their marijuana laws, so decriminalizing or legalizing in different cases. Today, marijuana is legal for medical use in 38 states and recreational use in roughly half of all states, plus the District of Columbia. But it still kept marijuana as illegal on a federal level.

as a Schedule I drug, so the government doesn't recognize it for medical use, and that's made getting safety approvals and government funding necessary to study the drug really difficult. So essentially, researchers say it's like they've been handcuffed all these years, right? And the handcuffs are just sort of coming off. Should we use it in place of an opioid? Should we use it in the place of another pain medication? Where and how should it fit into medicine?

We don't know. So now you'll see these scientists emerging in this natural health field, really opening up the field so that they can evaluate the therapeutic effects, which patients already know that cannabis has. Meanwhile, all these states have legalized marijuana and they're trying to figure out now, how do we establish a public health response to make sure people are safe?

aware of what they're taking as consumers, aware of what they're putting in their bodies, similar to what we have around, say, cigarettes or alcohol. Okay. And has there been success on that front? Is there consistency in what people are getting across this country, or at least consistency in the labeling of what people are getting across this country? Oh, no, absolutely not. Certain states have better, I think, testing and safety standards than others.

But no, I mean, essentially, it's on you to sort of be an expert both about like reading labels and figuring out what it is exactly you're taking and then also figure out what amount works for your body. I mean, and it seems like there is really wide variations. The problem is that

you know, people don't always know their own limits. They don't always know what they're taking and there can be real health consequences as a result. Not to mention this stuff's just generally a lot stronger than it used to be, right? Yeah. So the products out there are a lot stronger than the sort of dime bags that were floating around, you know, in the early 2000s. Over the last 25 years,

The government has been testing the percentage of THC in marijuana seized by the Drug Enforcement Agency, and they have seen that the percentage of THC has more than tripled in those samples from 5% to 16%. This sounds all very messy, Maren. As we enter a new year and approach this country with this potent drug that a whole lot of people love to take, that increasingly people are taking every day with this patchwork of

of laws and a whole, you know, inconsistent patchwork of regulations. Is anyone having buyer's remorse on all the legalization we've done?

Definitely. There are some people who argue that legalization was a mistake, as they point to these health consequences that I've been noting. They say that it hasn't really had the sort of positive impact on racial disparity in the criminal justice system that they expected it to. And they point out that, yeah, essentially, this is creating a new public health problem that researchers

just really have not had the time or ability to get a handle on before so many people started consuming marijuana. It is unfortunate that it's on the consumers to kind of figure out what is...

going into their bodies and whether or not it's good for them. But that is the reality of where we're at right now. It is a brave new world with regard to marijuana legalization in this country. It is probably harmless for a huge number and helpful even for a huge number of people out there. But it doesn't mean that it's perfectly safe and harmless for everyone. And I think people are going to have to, while the government sort of figures out a public health response to this, they're going to have to really think about themselves and make sure that they feel healthy with what they use.

Maren Kogan, you can read her joint on weed at Vox.com. It's called How Weed Won Over America. I'm Sean Ramos from Next Up on Today Explained. As we so often do, we're heading to Canada to find out if we can learn anything from our neighbors to the north who didn't just legalize state by state or province by province in their case. They legalized federally.

Support for today explained comes from Shopify as it has before as it does again. 2025 new year new opportunities Shopify says maybe this is the year you finally start that business that one you've been dreaming of since you were a kid but every time you thought of it you got overwhelmed with questions. How do I come up with a brand you said to yourself? How do I sell stuff to people you wondered and wait what am I even going to sell? Well that's

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Why do so many of us get happiness wrong? And how can we start to get it right? I mean, I think we assume that happiness is about positive emotion on all the time, right? Often very high arousal positive emotion, but that's not really what we're talking about. I'm Preet Bharara, and this week, Dr. Laurie Santos joins me on my podcast, Stay Tuned with Preet, to discuss the science behind happiness.

We explore job crafting, the parenting paradox, the arrival fallacy, and why acts of kindness might be the simplest path to fulfillment. The episode is out now. Search and follow Stay Tuned with Preet wherever you get your podcasts. Oh, today explains.

James McKillop sits in the Peter Boris Chair in Addictions Research at McMaster University and St. Joseph's Healthcare in Hamilton, Ontario. But he's also from the United States, so he was the ideal doc to ask, what's up with legalization?

Legal weed in Canada compared to America, we started with weed's legal status north of the border. Well, cannabis has been legal now federally for just over six years. And even before that, cannabis was legal for medical purposes since 2001. So it's been legal in one form or another for nearly 25 years. And...

Why did Canada legalize weed fully? So fundamentally, the approach was to apply a public health strategy to cannabis and in particular to try to reduce harms and maximize benefits. The three big goals were to reduce youth access, to create a legal framework for adults to access cannabis, and to reduce burden on the criminal justice system.

Okay, so how are we doing on those three goals to reduce youth access, increase adult access, and reduce burdens on the criminal justice system six years into this experiment? Well, the good news is we haven't seen a sharp increase in youth consumption, which was a fear that a lot of people had. And although we haven't seen big decreases, it does seem like there haven't been those feared increases.

There have also been some other consequences that are not so positive, but the other things that are good include certainly many fewer arrests for cannabis and a fully realized large economic cannabis sector now. Okay. So we did reduce burdens on the criminal justice. We didn't necessarily increase youth access.

I assume adults are smoking more? That is the case. So right now, the rates of cannabis use in Canada are certainly at all-time highs. Some of that happened before legalization, but that's a trend that hasn't gone away. And especially if you look at not youth like teenagers, but young adults in their 20s, the rates are close to half in terms of folks reporting any use in the last year. So the overall rates of cannabis use are certainly high.

Where does that put Canada in terms of, I don't know, world rankings of pot smokers? Well, historically, Canada lagged the U.S. only in terms of overall rates. I think that actually the rate may be higher than the U.S. now, although it depends on the survey that you look at. But certainly it is near the top, if not at the top, globally. Wow. So Canadians are smoking a ton of weed. And it sounds like

You think that's not a good thing? Well, I think that it's a complicated picture six years in.

So as I said, some of the good things are it's a real economic marketplace. There's a lot of sales. The illegal market has been substantially displaced, but there have been some downsides too. I think the overall high rate of use is not great. But the other reality is a lot of people are concerned about how many storefronts we have. There's a cannabis shop on every corner, it feels like.

And there are concerns about burdens on the healthcare system too. Worrying uptakes in terms of the number of individuals going to emergency departments or urgent care centers, the number of individuals who are experiencing cannabinoid hyperemesis syndrome, that very unusual syndrome of acute nausea and vomiting that takes place in people who use cannabis frequently. There are increases in pregnant women who are seeking care for cannabis.

and increases in the proportion of impaired drivers who are testing positive for cannabis. So those are all kind of canaries in the coal mine for some pretty troubling trends.

How do the medical concerns compare to those with alcohol? And are we seeing fewer alcohol-related hospitalizations or driving infractions as a result? That's a great question. So I think that alcohol is in some ways the best comparator drug. And the reality is alcohol, despite being legal, has lots of harms. And those range from

acute harms like driving while intoxicated and physical and sexual assaults to chronic harms like cancer. The U.S. Surgeon General this morning is calling for new warnings on alcohol products. In a statement in the last few hours, the Surgeon General said alcoholic beverages are a leading cause of cancer and should carry labels similar to those you find on cigarettes.

Light to moderate drinking was associated with reductions in overall brain volume. There's a really complicated and important relationship between alcohol and things like depression and anxiety in particular. And in a lot of ways, cannabis has a somewhat more favorable profile, although we don't have a great sense for whether the increase in cannabis use and the increase in cannabis sales...

legal sales has offset some of the harms from alcohol. What I can tell you is that if you look nationally, the alcohol retail sales have not changed all that dramatically. So Canadians spend about $2 billion a month on alcohol, and that has been very stable from prior to legalization to the current date.

Along that same time period, there has been a skyrocketing sales of legal cannabis. And so it seems like what's happening is the legal cannabis market is displacing the illegal market, but it's not really changing the amount of drinking all that much, which probably suggests that the amount of benefits in terms of reducing alcohol harms are going to be limited. You mentioned that there's a pot shop on every corner, it seems like, in Canada these days. Are you seeing an economic...

boom? There have been aspects of the cannabis economy that have been boom-like, but also bust-like. The reality is the stocks for a lot of the producers prior to legalization were sky high. And those stocks unfortunately dropped in value after legalization when things recalibrated a bit. A lot of the pot shops open and then unfortunately close because it turns out the markets are already somewhat saturated.

And there are some pretty insidious aspects of this, too, because when you have cannabis shops on every corner, even though advertising is prohibited, that becomes a form of advertising. So I have young kids and they see cannabis stores all over the place, sometimes two or three in a given strip mall.

And the other thing is, I've heard from my patients that when they're trying to quit or even reduce, having cannabis stores everywhere is a real challenge. And so I think that even though there are some economic benefits, we are right now reckoning with some of the harms also. Has someone done this better than Canada? I mean, do you guys look at the Netherlands and say, you know, oh, they had a great model. Is there a good model?

example of how to legalize marijuana out there? I'll tell you, Sean, what I think is the best model. And I think that Canada has done on balance a good job, but maybe not a great job. And where I see the best implementation is actually in Quebec. Also Canada. Also Canada. So one of the things that's interesting about Canada is that

cannabis is federally legal, but it is implemented by the provinces. So there are slightly different models across the provinces and territories. And there are some interesting natural experiments that are happening as a result. And as you probably know, Quebec often marches to the beat of a different drum compared to other provinces in Canada. They speak a whole different language. They speak French and

And there are many great qualities about Quebec, but in this case, they are probably the most different from the other provinces and territories because they have a higher age of access, 21 rather than 19.

They prohibit any edibles that look like candy to keep them out of the hands of children. So you can get cannabis cauliflower or cannabis broccoli or beets, but you can't get cannabis chocolate. They have a provincial monopoly, which means you can only buy cannabis from stores that are administered by the province, which means you can control how many stores you have.

And you can have really rigorous ways of making sure that kids or teenagers are not coming in and buying cannabis because they're similar to, for example, the ABC store in North Carolina or other state monopolies around alcohol. So in many ways, Quebec has implemented a

more stringent public health model. And we've actually seen in studies, not from my group, but from other groups, that some of the harms that are observed in Canada are not present when you look specifically at Quebec. So if there was a model I would recommend, it's probably that one. You know, let me close by asking you this, James. It's a new year. People are thinking about who they want to be, how they want to change, what resolutions they're making and whatnot.

For people who are smoking a lot of weed, considering taking up weed, considering quitting weed, as a medical professional who, yes, lives in Canada, but is actually from the United States, what would you say to your fellow Americans who are living in a state where this is now legal and who are certainly living in a country where their federal government isn't in a rush to solve this problem of the marijuana patchwork we have across the United States?

Well, Sean, given that it's January and a lot of people already consider dry January and abstaining from alcohol, I would absolutely encourage them to think about taking a month off from weed also, especially if they're frequent users.

The reality is, as a psychologist, I see a lot of people who struggle with their cannabis use. It's the number one problem in our young adult substance use program. And taking a month off is a great way to kind of take stock of whether or not you have a problem. If it's easy, then you'll save some money. You might clean out the mental cobwebs. Your lungs will thank you.

If it's hard, you may want to think about whether you need to talk to a health professional. And so to me, new year, new you, it's a great time to think hard about your relationship with pop. Dr. James McKillop, McMaster University. Go Marauders? That's a good one. Abhishek Artsy made our show today. He was edited by Amna Alsadi, fact-checked by Laura Bullard, and mixed by Andrea Christensdottir and Patrick Boyd. This is Today Explained. Today Explained.