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A Breakthrough in Pain Management Without Opioids
2025/2/18
Chasing Life
K
Kira
S
Sanjay Gupta
Kira: 听众 Stephanie 想了解 FDA 新批准的止痛药与现有止痛药有何不同，希望了解更多关于这种新药的信息。
Sanjay Gupta: 作为一名神经外科医生，我经常处理疼痛患者，因此对新的止痛选择非常关注。美国在过去 25 年里没有批准新的止痛药物，而 Jurnavax (suzetrogene) 的出现是一个重大突破。它通过阻止疼痛信号的传递来发挥作用，与阿片类药物通过作用于大脑来减轻疼痛的方式完全不同。Jurnavax 不会引起欣快感，因此没有成瘾风险，但可能有一些副作用。目前，它主要用于治疗急性疼痛，如骨折或术后疼痛。虽然在慢性背痛方面的效果不佳，但 Jurnavax 的出现为疼痛治疗提供了一个新的选择。
Deep Dive
The FDA has recently approved a new non-opioid painkiller, Jurnavax. Unlike opioids that dull pain signals in the brain, Jurnavax works by preventing pain signals from firing in the first place. This groundbreaking medication offers a new hope for pain management, although it's currently approved for acute pain only.
- FDA-approved non-opioid painkiller Jurnavax
- Works by preventing pain signals from firing
- Different mechanism of action compared to opioids
- Effective for acute pain, limited efficacy for chronic pain
- Potential side effects: itching, muscle spasms, rash
Shownotes Transcript