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Angela Duckworth
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Rebecca Lee Douglas
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Stephen Dubner
以《怪诞经济学》系列著名的美国作家、记者和广播电视人物。
Angela Duckworth：本期节目探讨了长寿的奥秘，特别关注基因、生活方式和人际关系对长寿的影响。研究表明，基因在长寿中扮演着重要角色，尤其是在90岁以后。然而，健康的生活方式，包括健康饮食、规律运动和不吸烟，同样至关重要。此外，良好的人际关系对健康长寿也起着关键作用，哈佛成人发展研究表明，人际关系是健康长寿的关键因素之一。她还分享了自己为了保持健康长寿而采取的一些措施，例如每周三次跑步时与朋友通话，以及每年至少与密友见面一次。她认为年轻时过分追求事业而忽略人际关系是一个遗憾，但她也承认，事业上的成功为她现在拥有更多的时间和资源与朋友相处打下了基础。
Stephen Dubner：他本人并不想无限期地延长寿命，也不确定自己是否想活到126岁（目前已知人类最长寿命）。他更关心健康预期而非寿命预期，即在健康状态下生存的时间。他认为对青春之泉的追求，尤其是在精英和富人中，有所复苏。他讨论了“超级长寿者家庭研究”项目，该项目旨在找到导致长寿的基因，并开发出模拟这些基因的药物。他还提到了利用小鼠进行的“共生”研究，该研究表明，连接年轻小鼠和年老小鼠的循环系统可以逆转大脑衰老。此外，他还提到了滚石乐队成员Keith Richards仍然活着的事实，这令人震惊，因为他吸食过大量的毒品。他认为Keith Richards或许应该获得诺贝尔奖，因为他仍然活着。
Angela Duckworth: This episode explores the secrets of longevity, focusing on the impact of genetics, lifestyle, and interpersonal relationships on longevity. Studies show that genes play an important role in longevity, especially after the age of 90. However, a healthy lifestyle, including a healthy diet, regular exercise, and not smoking, is equally important. In addition, good interpersonal relationships also play a key role in healthy longevity. The Harvard Adult Development Study shows that interpersonal relationships are one of the key factors in healthy longevity. She also shares some of the measures she has taken to maintain healthy longevity, such as talking to friends while running three times a week, and meeting close friends at least once a year. She believes that it was a regret to neglect interpersonal relationships in her youth due to excessive pursuit of career, but she also admits that career success has laid the foundation for her to have more time and resources to get along with friends now.
Stephen Dubner: He himself does not want to extend his life indefinitely, nor is he sure whether he wants to live to 126 years old (the longest known human lifespan). He cares more about health expectancy than life expectancy, that is, the time spent in a healthy state. He believes that the pursuit of the fountain of youth, especially among the elite and the wealthy, has revived. He discussed the “Super Centenarian Family Study” project, which aims to find the genes that lead to longevity and develop drugs that mimic these genes. He also mentioned the “parabiosis” study using mice, which showed that connecting the circulatory systems of young and old mice can reverse brain aging. In addition, he also mentioned the fact that Keith Richards of the Rolling Stones is still alive, which is shocking, because he has taken a large amount of drugs. He believes that Keith Richards may deserve a Nobel Prize because he is still alive.
Deep Dive
The episode begins with a discussion on the Super Agers Family Study, which investigates the genes contributing to longevity in people who live into their 90s and beyond.
Shownotes Transcript