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cover of episode Everything you've heard about lactose is wrong

Everything you've heard about lactose is wrong

2023/3/9
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ZOE Science & Nutrition

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D
Dr. Will Bulsiewicz
J
Jonathan Wolfe
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Jonathan Wolfe: 本期节目讨论了乳糖及其相关的不耐受问题。过去20年来,我对乳糖的认知存在误区,认为乳糖不耐受非常危险。实际上,乳糖不耐受的真相比我们想象的要复杂得多。通过与Dr. Will Bulsiewicz的讨论,我重新认识了乳糖,并了解到一些改善乳糖不耐受症状的方法,例如减少乳糖摄入量,选择发酵乳制品,补充乳糖酶,以及改善肠道菌群等。 Dr. Will Bulsiewicz: 乳糖不耐受并非像人们普遍认为的那样危险,它只是引起消化系统不适,但不会危及生命。乳糖不耐受的根本原因是体内缺乏足够的乳糖酶来分解乳糖,导致乳糖在肠道中被细菌发酵,产生气体和其它不适症状。改善乳糖不耐受症状的方法包括:减少乳糖摄入量,选择发酵乳制品(如酸奶、开菲尔),服用乳糖酶补充剂,补充益生菌(如嗜酸乳杆菌)和益生元(如半乳寡糖),以及改善整体肠道健康。通过这些方法,可以提高乳糖耐受性,不必完全避免乳制品。乳糖本身作为一种条件性益生元,对肠道健康有益,是婴儿的首选碳水化合物,对肠道菌群发育有益。 Jonathan Wolfe: 过去20年里,我一直认为自己必须完全避免所有乳制品,因为我被诊断为乳糖不耐受。但实际上,许多乳制品(如硬质奶酪、酸奶)的乳糖含量很低,我可以食用而不会出现不适症状。这说明乳糖不耐受者并非必须完全避免所有乳制品,而是要根据自身情况调整乳糖摄入量。此外,通过改善肠道健康,也可以提高乳糖耐受性。

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Lactose intolerance occurs when the body lacks enough lactase to break down lactose, leading to malabsorption and symptoms like bloating and gas.

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Lactose is usually only discussed in the context of intolerance. This intolerance can make us feel bloated, gassy and uncomfortable. But from cow’s milk to yoghurt and even breast milk, lactose is everywhere! So, can it really be that bad for us?

In today’s short episode of ZOE Science & Nutrition, we’re joined by Dr Will B. to find out. 

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Studies referenced in the episode:

Nature: How humans’ ability to digest milk evolved from famine and disease)

PubMed Central (PMC)

Effects of Prebiotic and Probiotic Supplementation on Lactase Deficiency and Lactose Intolerance: A Systematic Review of Controlled Trials)

PubMed Central (PMC)

Improving lactose digestion and symptoms of lactose intolerance with a novel galacto-oligosaccharide (RP-G28): a randomized, double-blind clinical trial)

PubMed Central (PMC)

Impact of short-chain galactooligosaccharides on the gut microbiome of lactose-intolerant individuals)

https://www.hopkinsmedicine.org/health/conditions-and-diseases/lactose-intolerance

The Importance of Lactose in the Human Diet: Outcomes of a Mexican Consensus Meeting:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893676/ 

Episode transcripts are available here).

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