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cover of episode E26: State of Venture Capital, plus fan questions on longevity, decentralization & quantum computing

E26: State of Venture Capital, plus fan questions on longevity, decentralization & quantum computing

2021/3/20
logo of podcast All-In with Chamath, Jason, Sacks & Friedberg

All-In with Chamath, Jason, Sacks & Friedberg

AI Deep Dive AI Chapters Transcript
People
C
Chamath Palihapitiya
以深刻的投资见解和社会资本主义理念而闻名的风险投资家和企业家。
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David Friedberg
美国企业家、商人和天使投资者,创立并领导了The Climate Corporation和The Production Board。
D
David Sacks
一位在房地产法和技术政策领域都有影响力的律师和学者。
Topics
David Friedberg:衰老是一个生物过程,理论上可逆转。通过基因表达、特定化合物(如二甲双胍、雷帕霉素)和生活方式的改变(如禁食、运动)可以促进长寿。 Chamath Palihapitiya:他个人采取预防措施,包括服用他汀类药物、二甲双胍和维生素,并定期进行全身MRI和心脏扫描,以尽早发现潜在健康问题。他还推荐Prenuvo公司提供的全身MRI服务。 David Sacks:对长寿技术持谨慎态度,认为目前的技术仍处于早期阶段。 Chamath Palihapitiya:比特币代表货币与国家的分离,其价值取决于人们对其的信仰,并可能成为对抗政府无限印钞的工具。去中心化金融(DeFi)将使所有资产金融化,从而简化税收。 David Sacks:虽然比特币交易记录在区块链上,但政府仍可以通过追踪资产的最终持有者来进行税收。 Chamath Palihapitiya:量子计算在未来十年内,主要应用于模拟量子态,从而改进对材料理化性质的建模,并在材料科学、制药等领域取得突破。真正意义上的量子霸权,例如破解RSA加密,则还需要更长时间。 David Sacks:量子计算目前仍处于研发阶段,属于政府而非私营部门应该资助的领域。 Chamath Palihapitiya:风险投资领域正在发生巨大变化,包括参与者构成、资金规模和融资方式等方面。 David Sacks:风投行业正在发生转变,创始人越来越看重个人投资者而非风投公司,这使得中小型风投公司面临挑战。 Chamath Palihapitiya:股权众筹的兴起为创业公司提供了一种新的融资方式,降低了融资门槛,并为投资者提供了更多机会。

Deep Dive

Chapters
This section discusses the evolving landscape of venture capital, highlighting changes in founder demographics, funding trends, and the growing importance of individual investors over institutional firms.
  • Venture capital is experiencing significant shifts, with more changes in the last decade than in previous decades.
  • Founder demographics are diversifying, although there is still a lack of representation for Black and Hispanic founders.
  • The trend is moving towards solo capitalists and individual investors, challenging traditional VC firms.
  • There is an inflation of investment money, leading to higher valuations and larger funding rounds.
  • The market is increasingly becoming founder-friendly, with non-dilutive funding options gaining popularity.

Shownotes Transcript

View the State of VC deck here:

https://rb.gy/wfan6j)

Follow the besties:

https://twitter.com/chamath)

https://linktr.ee/calacanis)

https://twitter.com/DavidSacks)

https://twitter.com/friedberg)

Follow the pod:

https://twitter.com/theallinpod)

https://linktr.ee/allinpodcast)

Intro Music Credit:

https://rb.gy/tppkzl)

https://twitter.com/yung_spielburg)

Intro Video Credit:

https://twitter.com/MikeSylvan)

Referenced in the show:

Lifespan by David Sinclair:

https://rb.gy/etzzmk)

Prenuvo:

https://www.prenuvo.com)

Gumroad Equity Crowdfunding:

https://republic.co/gumroad)

Backstage Equity Crowdfunding:

https://republic.co/backstage)

Show Notes:

0:00 Bestie intro & poker talk

5:49 Fan question: Longevity & Biohacking, Chamath's health regimen

12:54 Fan question: Decentralization, separation of currency & state, will governments fight back against crypto?

22:48 Fan question: Quantum computing's potential impact, why heavy R&D technologies should are better suited for government funding rather than the private sector

33:33 Chamath's thesis behind deep tech investing

37:25 State of VC & how it's changing in terms of demographics, new access to capital, deal size & more

48:49 Trend of founders caring more about individual investors rather than firms, who is well-positioned & who is left out?

55:00 Why growth-stage firms could become less relevant: undifferentiated capital, routing around dilution, brand matters more in the early-stage; how Pipe & Clearbanc are revolutionizing non-dilutive funding

1:04:00 Summarizing the changing landscape of venture capital, how startups can best position themselves in a full lifecycle, innovations in equity crowdfunding, opportunity for entrepreneurs