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cover of episode E65: VC markup dynamics, Russia/US tensions over Ukraine, Altos Labs raises $3B, Stripe mafia & more

E65: VC markup dynamics, Russia/US tensions over Ukraine, Altos Labs raises $3B, Stripe mafia & more

2022/1/29
logo of podcast All-In with Chamath, Jason, Sacks & Friedberg

All-In with Chamath, Jason, Sacks & Friedberg

AI Deep Dive AI Chapters Transcript
People
C
Chamath Palihapitiya
以深刻的投资见解和社会资本主义理念而闻名的风险投资家和企业家。
D
David Friedberg
美国企业家、商人和天使投资者,创立并领导了The Climate Corporation和The Production Board。
D
David Sacks
一位在房地产法和技术政策领域都有影响力的律师和学者。
Topics
Chamath Palihapitiya:讨论了投资和交易的区别,以及如何应对市场低迷情绪带来的负面影响。他强调要区分投资和交易,避免将两者混淆,并分享了他通过减少关注市场波动来控制自身情绪的方法。 David Sacks:阐述了风险投资的收益与市场波动之间的反向关系,以及风险投资公司作为市场价格接受者的角色。他认为,在市场低迷时期,投资机会反而更多。 David Friedberg:分析了风险投资公司不愿进行估值下调的原因,以及这种做法对市场的影响。他指出,这种做法会给风险投资公司带来压力,并可能导致市场估值出现偏差。

Deep Dive

Chapters
The hosts discuss the challenges of navigating a volatile market, emphasizing the importance of distinguishing between investments and trades. They highlight the artificial pressure on venture firms to consistently drive valuations up, even when business performance doesn't justify it. The conversation touches upon the disincentives for venture firms to take markdowns and the need for entrepreneurs to prioritize sustainable growth and realistic valuations over chasing inflated rounds.

Shownotes Transcript

0:00 Chamath's preferred cosplay 1:35 Reflecting on bad investment decisions and markup dynamics

15:20 Rising tensions between US and Russia over Ukraine, Putin's demands, NATO negotiations as the underreported key piece, Obama's savvy Russia dealings

39:16 Bill Ackman buys the Netflix dip, Tesla and Microsoft crush earnings, the Fed signals rate hikes

55:18 Altos Labs raises $3B in the largest Seed round ever, incredible Yamanaka factors breakthrough, dynamics of a richly capitalized bio-moonshot

1:04:08 The Stripe Mafia, Bolt CEO punches up, reflecting on old emails

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https://twitter.com/chamath)

https://linktr.ee/calacanis)

https://twitter.com/DavidSacks)

https://twitter.com/friedberg)

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https://twitter.com/theallinpod)

https://linktr.ee/allinpodcast)

Intro Music Credit:

https://rb.gy/tppkzl)

https://twitter.com/yung_spielburg)

Intro Video Credit:

https://twitter.com/TheZachEffect)

Referenced in the show:

https://www.bloomberg.com/opinion/articles/2013-05-30/bitcoin-the-perfect-schmuck-insurance)

https://twitter.com/DavidSacks/status/1480716684038049796)

https://medium.com/@jason/do-the-work-skip-the-party-8f2864560195#724a--share-10-78)

https://www.nytimes.com/2022/01/16/world/europe/russia-ukraine-invasion.html)

https://www.defense.gov/News/Transcripts/Transcript/Article/2910061/pentagon-press-secretary-john-kirby-holds-a-press-briefing)

https://www.theatlantic.com/magazine/archive/2016/04/the-obama-doctrine/471525)

https://www.history.com/news/nato-article-5-meaning-history-world-war-2)

https://www.latimes.com/opinion/op-ed/la-oe-shifrinson-russia-us-nato-deal--20160530-snap-story.html)

https://www.worldometers.info/gdp/gdp-by-country)

https://www.atlanticcouncil.org/blogs/natosource/obama-does-not-believe-invading-ukraine-or-saving-assad-makes-putin-a-player)

https://www.euractiv.com/section/global-europe/news/germany-agrees-to-axe-nord-stream-2-if-russia-invades-ukraine)

https://www.wsj.com/articles/william-ackman-takes-stake-in-netflix-11643236690)

https://tesla-cdn.thron.com/static/WIIG2L_TSLA_Q4_2021_Update_O7MYNE.pdf?xseo=&response-content-disposition=inline%3Bfilename%3D%22tsla-q4-and-fy-2021-update.pdf%22)

https://www.microsoft.com/en-us/Investor/earnings/FY-2022-Q2/press-release-webcast)

https://www.cnbc.com/2022/01/26/fed-decision-january-2022-.html)

https://www.tcv.com/tcv-insights/netflix-case-study)

https://www.cnbc.com/2021/11/16/peloton-files-to-sell-1-billion-in-stock-offering-shares-drop.html)

https://www.drugdiscoverytrends.com/biotech-altos-labs-emerges-with-3b-in-funding-to-focus-on-cellular-rejuvenation-programming)

https://www.biorxiv.org/content/10.1101/2022.01.20.477063v1.full.pdf)

https://twitter.com/theryanking/status/1485784823641755648)

https://twitter.com/shaunmmaguire/status/1486082835974811650)

https://twitter.com/Jason/status/1486113945790214146)

https://twitter.com/shaunmmaguire/status/1486114773209006080)

https://twitter.com/Jason/status/1486121975311339520)

https://my.pitchbook.com/profile/107633-08/company/profile#deal-history/102358-00T)