The American Heart Association is mourning the loss of former CEO Cass Wheeler, who led the organization for over three decades. Wheeler's impactful leadership transformed the Association, expanding its global influence in public health, cardiovascular science, and community engagement. His legacy includes launching initiatives like 'Go Red for Women™' and the American Stroke Association, as well as advocating for improved cardiovascular care and public health legislation. A memorial service is being planned, and donations to the American Heart Association in his honor are encouraged.