We are at SMACC in Dublin - thanks to the Rosh Review,) an excellent board review question bank. Here are some of our favorite pearls. Do We Make Saves? Dr. Mervyn Singer "Is Survival Predetermined in the Critically Ill?"
Many critical care studies are negative, but in some cases this may be because critically ill patients don't have a uniform prognosis. Dr. Singer argues that some people may be "destined to die" and some may be "destined to live." So, it's not really us "saving the patient", it's just the math playing out. Interventions may be harmful or futile in one group but beneficial in the other. For example, Dr. Singer references the CORTICUS trial of steroids in septic shock. This was a negative trial. Dr. Singer asserts that some evidence (of not great quality), purports that the sickest patients could benefit from steroids, while this same intervention could be deleterious in the healthier ones. Problem: many of the studies that go back and re-analyze these groups looking at the sickest or least sick patients? They perform subgroup analyses, a form of data dredging that must be taken with a huge grain of salt.
Favorite Pearls
Dr. Suzanne Mason - "Acute Care of the Elderly"
Dr. Victoria Brazil - "So You Think You're a Resuscitationist?"