Auto-brewery syndrome, also known as gut fermentation syndrome, is a rare condition where the body produces alcohol from carbohydrates consumed through food due to yeast overgrowth in the gut. It can lead to symptoms like drunkenness and fatigue without actual alcohol consumption.
The FDA has added a warning to GLP-1 weight loss drugs like Ozempic and Wegovy about the risk of pulmonary aspiration during general anesthesia or deep sedation. These drugs slow stomach emptying, which can increase the risk of aspirating stomach contents during surgery.
Motoric cognitive risk syndrome is a condition characterized by slow walking speed and self-reported cognitive complaints. It is associated with an increased risk of dementia and is considered a pre-dementia state.
Walking pneumonia, caused by Mycoplasma pneumoniae, is on the rise, particularly among young children. It was uncommon during the COVID-19 pandemic, but emergency room data now shows an increase in diagnoses, though testing for it is not always comprehensive.
Cymbalta (duloxetine) was recalled due to the presence of a potentially cancer-causing agent called nitrosamine. The recall affects thousands of bottles of the antidepressant, which is also used to treat neuropathic pain.
Exposure to light at night can disrupt the production of melatonin, a hormone that regulates sleep and protects neurons. This disruption has been linked to health issues like cancer, heart disease, diabetes, Alzheimer's, and even low sperm quality.
An at-home brain stimulation device uses transcranial direct current stimulation to prime nerve cells in the frontal brain regions, improving communication throughout the body. A phase two study showed significant improvement in depression symptoms after two and a half months of use.
McDonald's stopped selling quarter pounders in 12 states due to an E. coli outbreak linked to the burgers. One person died, and 10 others were hospitalized. The outbreak was likely caused by slivered onions used in the burgers.
This episode is brought to you by Amazon Prime. There's nothing sweeter than bacon cookies during the holidays. With Prime, I get all my ingredients delivered right to my door, fast and free. No last minute store trips needed. And of course, I blast my favorite holiday playlist on Amazon Music. It's the ultimate soundtrack for creating unforgettable memories. From streaming to shopping, it's on Prime. Visit Amazon.com slash Prime to get more out of whatever you're into.
♪♪♪
Please, Mom, don't send me away. I want to stay with you. It's only until all this is over. From Academy Award winner Steve McQueen, Blitz is a masterpiece. Your son did not arrive at his destination. You were meant to be looking after him. Where's my boy? Critics rave Elliot Heffernan is perfect. Saoirse Ronan is superb. I just want to go home. I did that for nothing.
This is not how.
Same people. I don't remember asking you a goddamn thing. It's mucous membrane, bro. You see? You see? You're stupid minds. Stupid. Stupid. If you just read the bio for Dr. Steve, host of Weird Medicine on Sirius XM 103 and made popular by two really comedy shows, Opie and Anthony and Ron and Fez, you would have thought that this guy was a bit of a, you know, a clown. Get your hand off my penis! Why?
You give me the respect I'm entitled to! I've got diphtheria crushing my esophagus. I've got Ebola virus dripping from my nose. I've got the leprosy of the heart valve exacerbating my infestable woes. I want to take my brain out and blast it with the wave, an ultrasonic, echographic, and a pulsitating shave. I want a magic pill for all my ailments, the health equivalent of Citizen Kane. Now in the tablet.
♪♪
It gives me street cred with wack alternative medicine assholes. Hello, Dr. Scott. Hey, Dr. Steve. And back from sabbatical, it's Lady Diagnosis. Hello, Lady Diagnosis. Hello, Dr. Steve. And my partner in all things, Tasty. Hello, Tasty. Tasty. Tasty. This is a show for people who have never listened to a medical show on the radio or the internet. If you have a question, you're embarrassed to take your regular medical provider. If you can't find an answer anywhere else, give us a call.
347-766-4323. That's 347. Poo head. Follow us on Twitter at Weird Medicine or at drscottwm. Visit our website at drsteve.com for podcasts, medical news, and stuff you can buy. Most importantly, we are not your medical providers. Take everything here with a grain of salt. Don't act on anything you hear on this show without talking it over with your health care provider. Lady Diagnosis, do you have a Twitter presence?
I do. What is it? I don't know. I think it's at lady diagnosis, actually. That would be my guess. Okay. Check out stuff.drsteve.com, stuff.drsteve.com for your
gifting needs coming up and the roadie is on there you can scroll down and see that or you can go to roadie.drsteve.com that's roadie.drsteve.com and see the roadie robotic tumor tumor that's a robotic tumor
robotic tuner that Brian May said that it was something that he wished that they'd come up with while he was still in the prime of his career. So it's an amazing thing. You just stick the peg on the tuning peg and click the string and it...
tunes it for you. You don't have to touch the peg or anything. It's really neat. And if you think that's too gimmicky, even though it's under 200 bucks in that vicinity, as a gift for someone in your family that does play a stringed instrument, you could get the Rody Coach. The Rody Coach is a training instrument
device that you clip to your guitar or other instrument and it will teach you how to play the damn thing. So it has perfect pitch and it will know if you're playing the right notes and it will teach you rhythm and teach you chords and all kinds of stuff. So it's really neat.
So check that out. Rodie, R-O-A-D-I-E dot Dr. Steve dot com. Check out Dr. Scott's website at Simply Herbals dot net. By the way, Dr. Scott, I've got a guy that wants to talk to you about maybe selling your Simply Herbals nasal spray. Yeah. And it's one of these...
places that sell CBD and stuff, but it's a really legit place. They're interested in the science. The guy that owns it had seizures, and the only thing that ever stopped his seizures was CBD. And if people aren't aware of that, CBD is the drug of choice for certain childhood refractory seizures. Right.
And then check us out at patreon.com slash weirdmedicine. All the normal world stuff goes there. All our YouTube shorts, these shows go there as soon as we're done making them. And they're not seen anywhere else. So check that out, patreon.com slash weirdmedicine. And then cameo.com slash weirdmedicine. I'll say fluid to your mama for a very little amount of money. All right? All right. All right.
Don't forget to check out Dr. Scott's website at simplyherbals.net. That's simplyherbals.net. And check me out on Normal World with Dave Landau. They're on Blaze TV, but also youtube.com slash at normal world. And we just finished recording.
Airing the Halloween special where we got to do serial killer therapy again, which basically was me doing telehealth because it's 2024 therapy on Carrie, Pinhead, Saw, and then a special guest.
Those are so funny. Yeah, those were fun. It was fun. I love that they let me do that. I just get to be the straight guy. But I did get to do a spit take on this one. Spoiler alert. Yeah, it was good. It was fun. And that was actually my idea. So I enjoy collaborating with them. They let me throw in a thing or two. And the spit take was taken with fluid that was obtained through a weird medicine mug. So I got a little plug in there, too.
A fluid plug. Yes, but Normal World, youtube.com slash at normal world. I have one on female ejaculation that is the answer to the question. There's no ambiguity. The science is there, so you can watch that one. And those go up on our Patreon afterward as well. I can't put them out on our public channel because it's...
Dave's stuff. I don't have their permission to do that, but we can put it in the Patreon. So check that out at patreon.com slash weird medicine. But I'm doing one now on ass play. And does it increase the risk of incontinence? Anal leakage. Yeah, anal leakage. Hmm. Hmm.
So, and anal fissures. Ooh. Joey Buttafuoco's girlfriend. Anyway, it's an old joke. I think I first told that one in 2007. All right. So, did you guys bring any stories today?
I have a weird condition. Okay. So this person says, it's weird. I'd eat some carbs and all of a sudden I was goofy and vulgar. Every day for a year I would wake up and vomit. Sometimes it would come on over the course of a few days. Yeah. And sometimes it was just like, bam, I'm drunk. Yep. From eating carbs.
Carbohydrates. So, does anybody know what this is? I know exactly what this is. You do? Oh, well, you looked it up. I did. You looked it up. I know what this is. Okay, let's see if he can get a bell. Go. Otto Burry Syndrome. Yes. Tacey. I mean, I don't know.
God damn it, Lady Diagnosis. It's supposed to be a quiz. Yes, I know. I'm asking Tacey to see if she can get it. Jesus. Okay. Anyway, yeah, it's auto-brewery syndrome. Hey, ring the bell. Yeah, you get a bell. I suck. Yeah, read the room. Jesus. No, I'm just kidding. It is auto-brewery syndrome. That's exactly right. So now you know so much about it, Lady Diagnosis. Why don't you talk about it? Yeah, that's all I know. Wait a minute.
Well, I can read what it says. Don't throw Diana in the boat. I am. Dr. Steve, I'm new here. No, you're not. It's gut fermentation syndrome. And it's a pretty rare medical condition that causes the body to produce alcohol from carbohydrates consumed through food. Now, I have had little old ladies...
come in that have urine drug screens that have alcohol in them. And I'm like, now, honey, you're not to be drinking no corn squeezings with these Percocets, you know. And she's like, well, honey, I ain't never touched a drap in my life.
And what it is is they have maybe a yeast infection and diabetes. So they've got sugar in their urine and they've got yeast eating the sugar and shitting out alcohol. And when they do a urine drug test, they've got a positive alcohol screen. It's always really low.
But anyway, yeah. But auto breweries in Brown are a little bit different. So, Scott, you know something about it. All I can think of is those ladies on Andy Griffith that were brewing their corn squeezings, and they were only selling them to people on special occasions. Oh, is that right? Well, and then Granny Clampett always had her rheumatism medicine. These two gals on, I'll make it quick, Andy Griffith, they were, of course, grandbabies.
make it moonshine. Yeah, of course. But they would only sell it to people if it was a special occasion. Oh, it sounds sort of like some of the dispensaries around here. So you'd have those guys come knocking on the door and say, well, sweetie, what's your special occasion today? You wouldn't believe it, but it's a president's birthday today. Well, I didn't know that. Well, I guess you could get you some corn squeezes. Oh, God. You know, sort of Andy Griffin goes, wait a minute. Ha ha.
I didn't know we were celebrating Flag Day up here. Andy Griffith is very important to people from our area, particularly since my first sexual encounter was with the fun girls. Fun girls. They say, hello, doll. Hello, Mernie. If you don't know what I'm talking about, just Google the fun girls. It wasn't the literal fun girls, but it was obviously who they...
took the inspiration from. I love it. Because they even talk the same. Yeah, I love it.
I don't know. Yeah, so that was a good one, lady diagnosis. As much shit as I gave you, auto brewery syndrome is the answer. Now, it can be really serious if this happens when, you know, if it kicks in while people are driving and stuff. Yeah, because it causes fatigue and all kinds of crazy symptoms. Well, it makes them drunk, too. It makes them sleepy. And then what will happen is this person, they may never drink, and they've got maybe Crohn's disease and or diabetes.
And then they have this auto brewery syndrome. They eat the products of fermentation in their gut or alcohol. They get pulled over and they get a DUI. And now I'm going to have to go testify for them. Now, they're still driving impaired. They just weren't drinking. Right. So, you know, I don't know how that would work exactly. They had a medical condition. I guess it depends if they knew they had it or not. Right. That's right.
I think that would make a difference whether they put you or, you know, took your license away. But they may say you can't drive until you get this under control. For example, someone with seizures, it's a medical condition. If they know they have it, they can't just go out and drive unless they've been cleared to drive.
And that's a tough one because if you get, you know, if you get, if you have a seizure while you're driving, most places you can't drive for X number of weeks and it can be in the months, you know, without a seizure before they'll let you drive again. So anyway, so what they do if you have auto brewery syndrome is they treat it with antifungals or anti yeast medications. You just kill the yeast in your gut.
And repopulate it with good bacteria. So you'll repopulate. Repopulate, right. But Saccharomyces can cause it. That's the yeast that makes beer and stuff. Gotcha. And it's a beneficial bacteria. We have it in our gut. Anyway, what do you think? Good job, Diane. That was a good one. Thanks for the bail. Thank you. Sure.
You robbed Tacey of a bell, though. I'm sorry, Tacey. I owe you. I didn't know what was going on either. Okay, well, there you go. You're nice, Tacey. She's sweet. All right, Tacey, you got anything? Thank you, Diane. Something, it's pretty shitty. It's neurological disorders. Do we want to hear about that? Fecal transplantation? No, neurological disorders. That's pretty shitty. Mm-hmm. Yeah!
All right. Sorry. I don't know what's wrong with me. I'm coming off well butren, and I think it's made me a little bit weird. I thought you had too many carbs this morning. It's really made me weird. All right. What you got? Well...
Give us one of them. Give us one of the neurological conditions. Yeah. Alzheimer's disease, multiple sclerosis, Parkinson's disease. All the fun ones. Those are neurodegenerative conditions. I actually have something about Alzheimer's if you want. Okay. I think those are good topics if you don't have a good article that you like.
We've talked about this before, but this is apropos to me. And, of course, it's all about me. New study finds link between sleep issues and dementia risk. Wow. Shocker. So older adults who feel drowsy during the day. Check. Check.
But lack enthusiasm for everyday activities. I can't say that's true for me. Nope. More likely to develop a condition that increases the risk of dementia. People with the condition known as motoric cognitive risk syndrome. Can we look that one up? Got it. Motoric cognitive.
Cognitive risk syndrome. Do you have it, Scott? Often walk slowly and report cognitive complaints. So, motoric would be movement, you know. Doctors not diagnose them with a walking disability or a dementia among study participants who reported excessive daytime sleepiness. Now, I have...
So sometimes when I'm driving down the mountain, I start falling asleep. That hasn't happened in a long time. Since I started taking this new mushroom supplement, I have not had that, which is pretty interesting. That's cool. It's an actual soft drink.
like an energy drink, but it has lion's mane and cordyceps in it. And I can't remember the name of it to save my life right now. Well, while you're looking at it, going back to the topic that Tacey brought up, the neurodegenerative syndrome. Yes, yes. If you talk about that also...
The mushroom drink benefiting your peripheral neuropathy, too. It should improve that stuff, too. Yeah, Odyssey Revive is the name of it. And I got it at—I bought it at like a CBD shop. And they just had them in there. I was like, well, this is cool. It doesn't have taurine. It doesn't have caffeine in it. But it's supposed to be good for, you know, brain fog and stuff. And—
So I bought one, and I really liked it, and I started getting it at Amazon. I get it for a half price at Amazon compared to what this guy is selling it for. So I think he's buying it at Amazon and just doubling the price. But it's Odyssey Revive, hydration and mood, and the one that I got was sparkling prickly pear. But it has lion's mane and cordyceps mushrooms, which are my two favorites.
go-to, I make my own tincture. And it's a very good tincture, I must say. Have you been using it? Yeah, well, I'm out of it now. Oh, are you? The one that you gave me was the bottle. You used that whole bottle? Yeah, hell yeah. Oh, yeah, good. Well, Tacey's got some, and I gave some to Joey Gay, the comedian who was in town recently. And...
That's Lady Di's new boyfriend. But I gave him some because he's interested in it. I'm always the last to know. Always the last to know. Poor Diane. He was a cutie, though. Yeah. Yeah, there you go. I mean, he is a cutie. And very, very nice, yeah. Yeah, very nice. I guess we can tell the story because it got out into the newspaper. Yeah, I heard. But, yeah, so our buddy Pete Davidson was in town.
And he came down just to visit, and he brought his friend Joey. And Joey Gay is a really nice guy, really funny comedian, and they travel together. They kind of—he took Pete—I wouldn't say he took him under his wing, but they—
Pete said he was the first person in comedy that treated him like a comic, like a human being. And Joey's just the nicest guy. Pete, sweetest, nicest person. And we were trying to be incognito, and he got into town, wanted to go see Venom. Okay. Because he hadn't seen it, so we had a little theater. In the shittiest mall you ever did see. It's unbelievable. There's no stores in this mall. No, no. There's no stores in the mall. It's like Spencer Gifts.
and a Zales jeweler, and this movie theater. Oh, and Annie's pretzels. Yeah, Annie's pretzels. I'd like to have one. So everything was fine. We sat down, and we watched a movie, and when we left, we just walked out. Everything was fine. All of a sudden, you know, peep, peep.
Pete, Pete. And all the employees from the, including the projectionists and stuff, from the movie theater came streaming out of the mall into the parking lot to get pictures with Pete. Oh, how funny. And now I kind of understand, you know, he's so gracious. I'm...
Sure, it's not fun, but he's so gracious about it and such a nice guy. But I photobombed every single one of those pictures. Which you should have because he really did get harassed everywhere we went. Even little corner restaurants that you would think nobody there would know. And why would anybody think that Pete would be in? Right. And where? Where? Okay, 1520.
Fix it now. No, I can't. I'm sorry. That's okay. Yeah, no, don't worry about it. It's fine. I'll edit it out later. Don't worry about it. Not like... Anyway, so...
And we—yeah, so I photobombed every single one of the pictures. And so there's all these people putting these things on their Instagram. Oh, you know, I randomly met Pete Davidson in the mall, and then there's this elderly weirdo going, ooh, in the background. In the background. It was so fun. Oh.
But, yeah, it was great. That's hilarious. But, yeah, I gave Joey some of the tincture, so I need to make some more. So I'm getting ready to make some. Yeah, you do need to make some more. It was a really fun couple of days, though. We had a great time. And those guys are from the Northeast, right, Staten Island, that area. Never had Southern barbecue, or if they had, they hadn't had the really good stuff. So we took them to the best.
barbecue place. Which one did you go to? Phil's Dream Pit. Look it up. Give them a plug. If you're ever in that area near Bristol Speedway. We live near Bristol Speedway. We've said that before. Oh, yeah.
Phil's Dream Pit is within driving distance from the Bristol Speedway. If you're coming for NASCAR and stuff like that, it is worth the trip. It's fabulous, yeah. And tell them Dr. Steve sent you. I don't get anything from it, but it was this guy's dream to do this business. Literally. And he's absolutely blown it out. Yep.
And so they went there twice, and then we went to another place, another barbecue place, where we accidentally just happened to run into Lady Diagnosis. Oh, how funny. So I'm sure she wasn't stalking us or anything. No. He didn't photo bomb my picture. No. Well, no, I didn't. I took that. I still have not gotten a picture with him.
He's the only one I have a picture with out of everyone that I've met. I thought, yeah, I might as well get one. Yeah, it was just so bad. Everybody harassed him. And then we didn't want to. Can we get one, too? Right, right. So I never do ask. I mean, we're his friends. But someday we'll get you that picture, Taze. I love it. Of course, the girls thought I was his mother. Oh, yeah, I forgot about that. Oh, my God. They're like, you've done such a good job with me.
Like, excuse me? Yeah.
You should be so proud. That is funny. Holy mother of God. Yeah, they were all like 20-somethings. And they were like, can we? You know, they were very nice. Because that was at the restaurant that our friend owns. And I had texted them. I said, listen, you know, just tell everybody to be cool. And they were totally, totally cool. But they were cute, and they were young, and they came out. And, yeah, that was the first thing. They looked at Diane and said, are you his mom? Mom.
I wish I had the wah, wah, wah, wah. But this one Facebook article talked about how, well, he must feel like he's better than everybody else. What? Because he was getting swarmed in a store in our town. Yeah. And he went out the exit, the emergency exit, and got in his truck and left. And she said, well—
He must feel like he's just better than everybody else. Oh, my God, no. And it's just like, no, he gets harassed 24-7. He absolutely does not think that. No, I know that. He is the most—I know, I'm telling people, but he is the most humble, sweet, just lovable guy. And— Jobs like a maniac. Yeah, but it's fun, though. He really—I don't want to say—
He has a very unique vehicle. Let's just say that. No sneaking around. Yeah. But it was...
Just a really delightful time, and it was fun having them. It was. And seeing that sort of level of celebrity where people just will not leave you alone. I mean, you can't just go to a restaurant and sit down, you know? So we had to sit out on a picnic table in front of the restaurant where nobody was. In the dark. Outside in the dark, yeah, to eat. And still, it happened.
They just came out there. Yeah. And he's so tall, too. So you notice him anyway. Right. You're going to notice him. Yeah. Yeah.
Yeah, and the hoodie's not. But he did have the hoodie pulled over and bent down. But to me, that makes him even more recognizable. You think? Yeah. Yeah, I mean. Because you're always looking, trying to see who's the one. If he's wearing a suit and tie or something, I don't think anybody would give him a second look. I bet you no one would have recognized him. But it made the newspaper and everything. Really? Yes. Not my photo. The one picture I didn't photobomb is the one that they got. Yeah, I wasn't there when they took that one.
That's funny. But anyway, he's delightful. We're huge fans and we're friends. And we love old Joey Gay, too. He's a really fun guy to be around. And I told Joey, heck, you can come down here. You don't have to bring Pete with you. We don't just like you because you're friends with him. Anyway, it was fun. It was fun.
Hopefully he'll get back down here soon and we're going to do an incognito trip and nobody's going to know about it. Anyway, tried to do that this time. It just didn't work. Oh, man. All right. Well, anyway, so let's talk fatigue and Alzheimer's.
So did you find anything about that motoric thing? I was temporizing to give you time. He was so kind. It's a pretty straightforward thing. It's called motoric cognitive risk syndrome. Correct.
And it's a predimension state that's characterized by slow walking speed and self-reported cognitive complaints. It's pretty vague. That I don't have. Yeah, it's pretty vague. Because everybody, all my trainees and residents and medical students are always walking 10 steps behind me because they can't keep up with me. Okay, I'm good on that. But you slowed down back when you were heavy dosing the statins a couple years ago. Did I? Oh, God, yeah. Yeah, you were shuffling around like Ed Parkinson's.
Well, that was when I had my back issue, though, wasn't it? No, no, no. That was prior to that. Prior to. No, when you had your back in, you were still going around like a wild child. Yeah, I was walking with a cane and crawling up and down stairs, though. But you were still moving pretty well. Okay. All right. For an old-timer. No, but these are things that patients state.
that don't require any kind of testing. Yeah. Right. It's self-reporting as opposed to being able to run a scan on them or a blood test or something. It's sort of short stance, or I mean short, what do you call it, when the steps that they take are short. Well, but Jim, we see that in...
Great amount of people that are aging anyway because people lose their proprioception. Yeah. And they have... Well, tell people what that is. Well, proprioception is just your body, your awareness of space and time where your body is. So being able to close your eyes... Every joint in your body that moves has a sensor in it that sends... Your brain says... All it does is say, this is the angle that this thing is at. And it's not a digital thing. It doesn't say, well, it's at 180 degrees. It's all analog. But it... And that's how you know...
When you close your eyes, I can point at Scott's nose and not be looking at it because my body knows where all those joints, what the ankles. But anyway, that's proprioception. Which is an incredible thing you think about. So we see a lot of folks as they age, they'll get poor proprioception. They'll get a little balance or instability anyway. And a little bit of neuropathy in their feet. They don't feel their feet so well. And so they get shortened steps anyway. So, yeah, it's just kind of a...
This is a very vague syndrome. Okay. Well, I don't have that, so that's good. That's why, okay, I brought that one up. So I thought dementia was something if you noticed it, you were less likely to have it. It's when you didn't know you had the problem that it was more dementia? No, a lot of people with early dementia know they have it. Early dementia, okay. That I didn't know. Because one of the first symptoms of, say, Alzheimer's-type dementia is a thing called anomia, meaning that they can't name things properly.
So they would look at this thing on my wrist and say, well, that's a thing that tells time rather than saying that's a wristwatch. And word searching is one thing, but just not being able to name things in general is an issue. And I've talked on this show about my professor in –
medical school who had an IQ of 220. And when he got dementia, the way that he described a deck of cards was he couldn't come up with the word deck of cards, but he said it's a concentric stack of thin laminates. That's what anomia sounds like in somebody with an IQ of 220. Okay.
Now, Lady Diagnosis, will you take that camera there and just sort of twist it toward you? Just twist it toward... There you go. There you go. That's good. Okay, thanks. Please, Mom, don't send me away. I want to stay with you. It's only until all this is over. From Academy Award winner Steve McQueen, Blitz is a masterpiece. Your son did not arrive at his destination. You were meant to be looking after him. Where's
My boy. Critics rave. Elliot Heffernan is perfect. Saoirse Ronan is superb. I just want to go home. I'll be back when I found my boy. One of the most enormous cinematic experiences in recent history. Blitz. Written and directed by Steve McQueen. Rated PG-13 and now streaming on Apple TV+. At Sierra, discover top workout gear at incredible prices, which might lead to another discovery. Your headphones haven't been connected this whole time. Awkward. Awkward.
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All right. Here's another new story. New FDA warning added to popular weight loss drugs. Uh-oh. FDA has updated the labels for all GLP-1 weight loss drugs with a warning about pulmonary aspiration during general anesthesia or deep sedation. Well, when I had my cataract surgery, they told me... Not to take it. ...for two weeks before. That's why now. Now we understand why. Yeah.
Yeah, there's a safety-related labeling change for the glucagon-like peptide 1 receptor agonist class. That's ozempic, ribelsis, waygovi, terzepatide, which is manjaro or zep bound.
And there have been rare post-marketing reports. And so that's phase four studies. Remember, the first studies, phase one, is just proof of concept, 10, 20 people. Phase two, maybe 300 people. And then phase three is 30,000 people, approximately, plus or minus. And then phase four would be post-marketing. That's where you have millions and millions of people.
people taking the drug and you can tease out extremely rare complications during phase four. And they said there have been rare phase four reports of pulmonary aspiration in patients receiving these agonists undergoing elective surgeries that require deep sedation. And if they had residual gastric contents, because one of the things is this stuff retains stuff in your stomach longer, right? Yeah, exactly. I did know that. Yeah.
And it slows movement of food through the gut. So that all makes sense. If they lied and ate stuff after midnight or if this stuff's really working and they didn't eat after midnight but they still have stomach contents because that's what the drug does, then they're more likely to aspirin.
So, you know, Dr. Scott, when they do a colonoscopy, they just lay you down on your side. They don't protect your airway. They just give you Michael Jackson's magic milk. And you're just breathing on your own. So that makes a lot of sense. Thank you. That's interesting. Well, I learned something today. That's crazy. Crazy talk. What about you, taste? No, I didn't learn nothing. She already knew it all. Yeah.
Anyway, all right. So there's that one. All right. Let's hit, okay. Can't shake that cough. Walking pneumonia is on the rise. Young children are increasingly being infected with bacteria that can lead to an illness known as walking pneumonia. This bacteria, and it's not really even a bacteria. It's sort of, it's weird. It's not a typical bacteria. Put it that way. Mycoplasma pneumoniae.
It was so uncommon during the height of the COVID pandemic that one medical journal ran an article saying maybe it's gone forever. Now, we did get rid of one strain of influenza, but I'll have to attest, yes, we didn't see a single case that we knew of of walking pneumonia. But we were calling everything COVID back then, too. So we may have just missed it. True.
It usually causes respiratory tract infections, can cause damage to the throat and windpipe and lungs. You get a...
Cough, usually. You might have a fever, sore throat, and all of that stuff. But then it's very gradual. And then eventually you just get this cough and no fever and no toxic stuff. Not as bad as whooping cough. Whooping cough causes a brutal cough that can break ribs and stuff like that. And you cough until you puke. And there's a vaccine for that, not one for mycoplasma.
The other place you may have heard of mycoplasma is you can get ureaplasma and other similar bacteria in the urinary tract infection. They're very hard to get rid of. So they've noticed an increase in emergency room data listing mycoplasma pneumonia as a diagnosis. Now, listen to me. That's...
They're using ER diagnoses. How many times do you think they actually tested somebody for mycoplasma? They just called them, oh, you've got walking pneumonia. Right. They test them for RSV. They test them for flu. That's not on the panel. Yeah, but they test them for other things. Well, you don't have these things. You've got to have walking pneumonia. That's correct. That would be my guess. And it's not commonly offered by labs like the flu, COVID, and other respiratory viral panels are. Mm-hmm.
And so I think that this may be a little bit of bullshit. It's just like when the CDC came out with that data and people jumped on it, that only 6% of people had COVID-19 on their death certificate. Right. And what they meant was as the primary diagnosis. So people and my point was.
As someone who does death certificates all the time, I was a medical examiner when I was in Vermont. So I'm trained on doing death certificates properly. Anyone, any doctor that coded someone who died during COVID as dying from COVID-19, they were doing the thing wrong. Okay.
So that's why only 6%. I would have thought it would have been more than that because most people don't know how to do effing, you know, death certificates properly. No one died as a principal diagnosis being COVID-19. It would be respiratory failure due to...
atypical pneumonia due to COVID-19, something like that. And that's a properly sort of crafted death certificate. So, you know, people jumped on that saying, well, you know, obviously the CDC is lying to us and all this kind of crazy stuff. And that wasn't it at all. It was just they were relying on data that was generated by people who weren't filling the forms out correctly. Yeah.
And I wonder if this isn't correct, too. Emergency room data. That's not data. That's people just going, well, I don't know what it is. I'm going to call it walking pneumonia. So I would love to. It would be a fun study.
Take all these people that got diagnosed with walking pneumonia in the ER and then actually do the gold standard test. See how many of them actually have mycoplasma. And so the treatment for mycoplasma is standard antibacterial stuff? Well, yeah, it's like erythromycin or doxycycline and those.
So the sort of more atypical antibiotics, too, to kill this stuff. And so that sometimes is an excuse to just give somebody an antibiotic. Well, you've got walking pneumonia, so here you go. And I'd like to say, too, if people don't recover from it very quickly, which does happen a lot with pneumonia, other things like percussive therapies that a lot of times...
The patients aren't told when they're in a hospital. They go in and they check them out. They get an antibiotic and they send them home. And maybe they have to come back two or three times for more antibiotics and steroids. Other things they can do are like percussive therapies, breathing treatments where they have the inspirometers or the acapella valves to actually make them exchange that can help those medications work better. It helped me a lot.
Heck yeah. When I had my bronchiectasis, they gave me this flutter valve thing. I always thought that was a joke. Oh, I use it all. You breathe into this device and it stutters. It won't let you breathe out a laminar flow. It keeps stopping your breathing. So it's like that and it flutters. And what that does is...
is it acts like percussive pulmonary, what we used to call pulmonary toilet, where they would percuss your back as a mucolytic. In other words, it would thin out the mucus and make it more accessible to be coughed on. And it really worked. It worked extremely well. I always thought it was a joke. And you can find them on Amazons and stuff like that. You can go buy them. Acapella bells. They look like little footballs or little kind of sausage-looking things. Yeah, it looks like a green football. Which is the exact opposite of the...
Incentive spirometer. Incentive spirometer. That one you suck in to increase your sort of tidal volume. Volume, right. Yeah. Anyway, yeah, very good. All right. You want another –
Let's do it. 7,000 bottles of antidepressants were recalled. Oops. Which one? Well, this is a bad one to be recalling. Thousands of bottles of the medicine duloxetine are being recalled because they may contain a potentially cancer-causing agent. Now, duloxetine is the generic name for Cymbalta, which we write piles of this stuff.
And the thing about Cymbalta is, you know, I work, part of what I do is work with cancer patients. And a lot of the chemotherapies kill cancer cells, but they also kill peripheral nerves. And so these people end up with horrible neuropathies, which is just nerve pain, shooting, tingling, burning, any type of pain where you have to use a paragraph to describe it. Most of the time that's going to be neuropathic. You know, if you have gallbladders, I have sharp pain right here.
But neuropathic pain is, well, I have some burning and feels like pinpricking and it moves up and down, maybe sometimes electricity. That's somebody that's talking about neuropathy. Duloxetine is the drug of choice for that. And not only that, it's an SNRI, serotonin norepinephrine reuptake inhibitor, as opposed to SSRI like Prozac.
And the SNRIs are pretty good for pain, too. They help turn down the pain signals from the dorsal horn of the spine, and you have a decreased perception of pain. So it's good for neuropathy, good for regular pain, decent for anxiety and depression, and may help regulate your sleep at the same time. And now it's generic, so it's dirt cheap. So this is a big blow.
The recall was voluntary and started by drug maker Tawa Pharmaceutical. So they must be a generic. They said, don't stop taking your duloxetine. Discuss the matter with your health care professional because they'll have certain lot numbers from a certain manufacturer. So you could talk to your pharmacist, too, and say, is my duloxetine that you gave me on the recall list? If they say no, you're fine.
But they're worried about a chemical called N-nitrosodiloxetine, and that includes the carcinogenic substance nitrosamine, which nitrosamines we see in soot and stuff like that when you char meat and things like that. They're toxic as swallowed and are suspected of causing cancer. But, I mean, we're talking minute, unbelievably, vanishingly small amounts in this.
This is what they call a class two recall, which is a designation the FDA uses to communicate how hazardous a recalled product may be. Class two indicates a product that may cause temporarily or medically reversible adverse health consequences where the probability of serious adverse health consequences is remote. So they're just being careful. But anyway, so if you're on duloxetine, don't freak out.
Go to the pharmacy and just see if what you have is on the recall, and they'll swap it out for you. Okay. Okie doke. Good. All right. Here's a fun one.
A deadly E. coli outbreak linked to McDonald's quarter pounders. Uh-oh. Uh-oh. Now, listen to this. An E. coli outbreak has been linked to the death of one person, prompted McDonald's to stop selling quarter pounder hamburgers in 12 states. So this is one of those things. I usually don't like knee-jerk responses to things. Like, for example—
If somebody writes an order in the hospital that they write it wrong and the Joint Commission comes and finds this chart and sees it, and then all of a sudden the health system goes, well, everyone has to change how they write these drugs. Instead of just go to the person and say, stop doing that, because everybody else was doing fine. So, you know, you're affecting it. But this is a case where.
A knee-jerk reaction is apropos because they suspected that these burger patties or it could have been the slivered onion toppings may have been the source of the outbreak. I'm always worried about onions and stuff like that, you know, fresh vegetables at fast food places because you always just wonder how long it's out there. Someone who works at
or owns a McDonald's, feel free to call in. This was in Colorado and 10 hospitalizations. So Rocco Burrow, our friend, you know, the actor who plays Tookie in the Dabbleverse, the Dabbler of the Year,
lives in Colorado, and he needs to not feed his little sister, who is actually his daughter, because the conceit originally was he was a 16-year-old living in his basement, and his daughter was actually his little sister. Anyway, he needs to avoid McDonald's until they get this straightened out.
If you ate a quarter pounder hamburger from McDonald's and have severe symptoms of E. coli, contact your health care provider. So what are the symptoms of E. coli? Diarrhea. Diarrhea. Diarrhea. Diarrhea. She had diarrhea, I'll tell you that. She had the green apple quicksand. Uh-huh. Green apple quicksand.
Diarrhea. Cha-cha-cha. Do you not hate that commercial? Diarrhea. It's literally the worst commercial. It is the worst commercial. I actually like it. What is it? Is it bismuth subsalicylate? It is. Nausea. What?
What is it? Something. Yeah, right. See? Heartburn. All I remember is, and diarrhea. Not your heartburn, indigestion, upset stomach, diarrhea. Oh, God. There you go.
And they accentuate diarrhea. It's separated by just a minute pause. In the most beautiful music ever. I don't know how beautiful it is, but yes, it is. I don't believe singing and dancing to diarrhea is a great way to... No, you're just thinking of... They've even got to dance for it. Shitting themselves while they're dancing. That's why I'm saying it's ridiculous. It's worse. Anyway, confirmed cases span 10 states, the most...
recent being reported in Colorado. So this is really where our food supply, it can't be perfect.
But they respond to this stuff really quickly. And we have the safest food supply in the world. And even then, stuff like this happens. So just a few people got sick. One person tragically died from this. But they're on it. So McDonald's stopped selling Quarter Pounders and all of its restaurants in Colorado, Kansas, Utah, and Wyoming. And this is being recorded November 9th, 2024.
And some of the changed restaurants in eight other states removed the menu item. And this would be Idaho, Iowa, Missouri, Montana, Nebraska, Nevada, New Mexico, and Oklahoma. All right.
The initial findings from the investigation indicate a subset of illnesses may be linked to slivered onions used in the quarter pounder and sourced by a single supplier that serves three distribution centers. So they just – they're working on it. All right? So that's the correct response to that.
And don't eat onions with your quarter pounder anyway. Why do we have to have onions in everything? Because they're free. Oh, is that what it is? I swear that. Because they're in everything. I mean, people put onions in, like, chicken salad and...
It's just like, why are you doing that? And then coleslaw could stop it. I can't eat that shit. Of course, again, it's all about me. All right. And then the last one I'm going to read, because this also applies to us. Scientists are linking more diseases to lights at night. Okay.
So it's the night sky over the North America has been growing brighter by 10 percent per year. I know as an amateur astronomer, light pollution is a problem.
But more and more research is linking all that light pollution to a surprising range of health consequences, including cancer, heart disease, diabetes, Alzheimer's disease, and even low sperm quality. And we've lost this contrast between light and dark, and our physiology is getting confused.
We really recommend that if you have LED lights for your chargers and stuff like that, that you cover those up. You need to sleep in total darkness if you can. And I'm guilty of not. We have a light that illuminates the front door, and it spills out into the top floor, and I need to just shut that door. Right.
We used to, we're so used to leaving that door open in case the boys needed something. Now they don't live here anymore. So, but yeah, so get more dark slate because the environment outside is messing up our internal clock because it's just so bright. If you live in the city,
It's terrible. It's crazy because of the skyscrapers like in New York. It starts getting, it looks like dusk at like three in the afternoon. As soon as the sun moves and it's hitting the buildings at an angle, everything seems dark out there. They're not getting enough vitamin D. And then at night, they're not getting any darkness because the place is just completely lit up.
And this can lead to a problem. So melatonin is produced when it's dark by the pineal gland in the brain. And it's a key player in this and it helps you sleep.
It protects neurons from damage. Actually, melatonin and the pineal gland regulate the immune system and stuff and may be involved in anti-inflammatory properties of the human body. And when you have even a little bit of light hitting your eyeballs at night, it suppresses its secretion. Time change. How does that affect the body? Yeah, it's not. Because it does. It sucks. It sucks.
You know what sucks the most? Sucks my... Your dogs don't know that time has changed. No, that is what sucks the most. Oh, it's the worst. They start looking at you like it's time to eat. Sugary gets me up at 6 a.m. Yeah. 6 a.m. Because she used to do 7, right? She used to do 7, yep. Lights up, dad. It's time to go play. Wow. Got to go back to sleep. I mean, but does it do anything physically to you?
Because I have a friend who says, well, I mean, you still get the same amount of sleep. It's just an hour difference. So what difference does it make? Well, it does mess with your clock, that's for sure. You know, what they're showing here is lab animals exposed to nighttime light show enormous neuroinflammation. That's inflammation of the nervous tissue. And one experiment on humans who slept immersed in weak light showed
had higher levels of C-reactive protein in their blood, which is a marker of total body inflammation. And we screen people for that for heart disease, you know, for heart disease risk. So what if you wear just something over your eyes? Yeah, that'd be fine. Is that enough or do your whole body have to be? No, no, no, no. It's coming through your eyes. Just your eyes. The eyes are the gateway to the brain. Low melatonin has been linked to cancer too, so, you know. Yeah.
So, yeah, we're going to have to do better with that. Get your sleep. And I bought Tacey these goggles, sleep goggles last year. They're some kind of highfalutin, high-tech sleep goggle thing that's supposed to help eliminate light and do some other things. And, of course, they're just sitting in the box. But I look at them and I say, I really need to try them about every day. Yeah, I walk by there. Well, she still hadn't opened that fucking box.
Every day. Oh, hey, just be glad she didn't box them back up and send them back and get the money and keep it. I may have had that experience in my former life, you know. Motivation. All right. One last thing. One last thing. At-home brain stimulation device targets depression.
This is a headset that can be worn at home to stimulate the brain and treat depression, and they passed an important research milestone. This tiny current from the headset is felt like a faint tingle and the results of a phase two. Now, this is in pre-marketing study. Phase two clinical trial published in the journal Nature Medicine, not some piece of crap little journal.
showed that people who used the device for two and a half months had a significant improvement in their depression symptoms. So what I'm looking at is a lot of things other than SSRIs. Feels like. Yeah, and pills. Just dumping buckets of serotonin into people's brain was—
It works for some people. There's no question these drugs have been lifesavers for a lot of people. But there's a lot of people still walking around suffering with depressive and mental illness for whom the standard drugs don't work. So we've got psilocybin coming. We have ketamine now. Yes.
And then we've got these, you know, neuro stimulators that may be coming. Can I add to that? And the trip app. Talking about the electric stimulation, one of the reasons I use electrical stimulation is on my needles. When I do acupuncture, it's been proven to increase the release of serotonin.
In your bloodstream. Makes sense. Just simple, simple needles, a little bit of stem, and it increases serotonin so people feel better. Without having to take a pill that goes to the tip of your toe just to get into your brain. Yeah, so this is kind of an interesting...
Yeah. You know, new research. This is transcranial direct current stimulation. It works by priming nerve cells in the frontal brain regions to more readily send messages throughout the body. Cool. And the study, this phase two study, one of the things they look at is safety. They didn't see any safety concerns with it. They did. Two people did get electrical burns, though, but I guarantee you they didn't follow the directions. They didn't put on properly. Yeah.
Yeah, it says they were caused by insufficient sponge moistening. So follow the instructions, people. So they're giving little ECGs, I guess. Sort of, yeah. Sort of like a mini one. It doesn't cause a seizure, though. No, of course not. So you can rent them. When it's going to come out, you'll be able to rent it for $100 a month or you'll be able to buy it for $500, which is actually a lot cheaper than I thought it was going to be. Oh, yeah.
Yeah. So, all right. Those are all my studies or topics. You guys got anything else? No, that's really... Mine were really crappy and I can't even find one of them. That's okay. All right. Number one thing, don't take advice from some asshole on the radio. All right. Let's try this one here. I don't know if we did this one or not. Dr. Scott, this is one about...
polyethylene glycol, a.k.a. Miralax. Hey, Dr. Steve. It's Albert from Albuquerque. Hey, Albert. Hey, listen, I wanted to touch base with you. How are you guys doing, first of all? Good, man. How are you doing? Cool. And tasty? Good. Wonderful. When you're not here and they do that, I answer for you. Oh, really? I'm fine. Thank you.
Let's talk about what Miralax is just for a second. It's polyethylene glycol. It's an odorless, colorless powder that you put in fluid and drink it, and it will cause the bowel to not absorb as much fluid.
from the lumen of the bowel, so you get less dry, hard skin.
turds and you have less constipation. That's what it's for. I do use Miralax. It's not one of those things you can just take today because you have constipation today unless you just take a ton of it. It is something that really is for people with chronic constipation to take on an ongoing basis. I usually counsel people if you're going to take it, take
And you get too loose, don't stop it. Just decrease the dose. Because if you stop it, now you're going to get constipated again. Now you've got to take three times more, and then you're going to be shitting out pure water, and then you're going to stop it and get constipated again. So you want to find some dose that will give you a normal bowel movement every day or every other day. But when I start blocking off a little bit, milk of magnesia is the thing that really does the thing for me. Sure.
And you said that, you know, active versus inactive stimulants. Would milk of magnesia be considered an active stimulant for moving your bowel? I know Miralax, you were saying, is considered, you know, kind of passive with the... And I viewed milk of magnesia the same way. I'm just kind of curious. It seems to be my go-to. When I'm stuffed up,
30 milliliters, that's 45 milliliters of milk and magnesia, and within 12 hours, I'm going to be comfortably moving everything through. I'm going to give him a bell. Give thyself a bell. Because it is very much like polyethylene glycol. Magnesium hydroxide is, or magnesium oxide both, increases the osmotic effect of the intestinal tract, so it draws water in. Mm-hmm.
So Miralax, it does some of that too, drawing water in, but mostly it helps to retain fluid. And then when you put little particulates...
in the bowel that can't cross the barrier. What it does is through osmotic pressure, the universe is trying to find an equilibrium. And to do that, it's trying to dilute out those little solutes that are in there. And the net effect is you have an increase in fluid in the bowel. And then you just, yeah, just...
It makes it easier to shit it out. The other thing that happens is, is the colon gets distended. And when the colon gets distended, what happens, Tase? It contracts. Exactly. Give yourself a bell. I have to live with her. That's true.
But, yeah, once it distends, so it is a little bit of a stimulant and an osmotic laxative. So that guy was exactly right. So, Dr. Scott, I'm going to look at the Super Chats. Myrtle Maness. All right, Myrtle. Gifted 10 Weird Medicine with Dr. Steve memberships to the waiting room, and those will be dispersed amongst the fluid family. Yay!
And I'm not booing the Fluid family. It just gives me the deuce chills every time I say it. But it is our YouTube channel. We don't really do a live stream thing. This is just a behind-the-scenes video of us recording our radio show. But if you would like to join with the people in the chat room, go to youtube.com slash at weirdmedicine.
And click join. And then just you don't have to actually join. Click accept gifted memberships. And Myrtle goes in there before every show and gives out between anywhere between five and 25 memberships every time. You don't have to be present to win.
All right. Okay. Anything else, Dr. Scott, over there? No, sir. We had a little bit of technical trouble and the live stream dumped out in the middle of it. And so we lost. If there were questions on there, we lost them. If you left one in there, just please come back next time and we'll do it again. We usually record anywhere between 11 and 2 on Saturdays, but sometimes on Wednesdays. So the best thing to do is...
Go to the YouTube channel, youtube.com slash at weirdmedicine, you know, the at sign, and then click the notification button. You'll get notified. And also follow us on Twitter. I refuse to call it X. Follow us on X. I don't know if people know what I'm talking about. And it's at weirdmedicine there as well, and I'll always put out an announcement there. Okay? Okay.
Okay. All right. Check out our Patreon at patreon.com slash weirdmedicine. Check out Dr. Scott's website at simplyherbals.net. And Tacey's over there destroying the studio. Thanks always. Go to Dr. Scott, Lady Diagnosis, Tacey. Thanks to everyone who's made this show happen over the years.
listen to our series xm show on the faction talk channel sirius xm channel 103 saturdays at 7 p.m eastern sunday at 6 p.m eastern on demand and other times at jim mcclure's pleasure and many thanks to our listeners whose voicemail and topic ideas make this job very easy go to our website at drsteve.com for schedules podcasts and other crap and uh thank you to say no more two dollar canadian um so it's what that's 50 cents you guys appreciate it uh
Says, oh, you are the best, Dr. Steven. So I'm in here. I'm making fun of Canadian money. So I should not have done that. Thank you. Say no more. No, you are the best. You're the best. Finding us after the YouTube channel crashed. So until next time, check your stupid nuts for lumps. Quit smoking. Get off your asses. Get some exercise. We'll see you in one week for the next edition of Weird Medicine. Thanks. Thank you. Thank you.