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cover of episode Can AI Crack The Biology Code?

Can AI Crack The Biology Code?

2025/6/3
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Short Wave

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Burleigh McCoy
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Emily Kwong
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Burleigh McCoy: 我认为人工智能已经彻底改变了蛋白质科学领域。我们现在可以以前所未有的速度和准确性预测蛋白质的结构,这对于理解生物学和解决各种问题至关重要。AlphaFold等工具的出现,使我们能够以前无法想象的方式探索蛋白质的世界,并设计具有全新功能的蛋白质。 Emily Kwong: 我对人工智能在蛋白质科学中的应用感到非常兴奋。它不仅加速了科学研究的进程,而且为解决人类面临的重大挑战提供了新的可能性。从疾病治疗到气候变化,人工智能驱动的蛋白质科学有望为我们带来革命性的解决方案。 Julian Bergeron: 我亲身经历了AlphaFold带来的变革。以前,我的实验室花费数月甚至数年才能确定一个蛋白质的结构,但现在只需几个小时。这使我们能够更快地推进我们的研究,并取得更多的突破。AlphaFold对我的研究产生了巨大的影响。 Pushmeet Kohli: 我认为开放获取对于科学的进步至关重要。通过使AlphaFold等工具易于访问,我们能够加速科学发现的进程,并使更多的人能够参与到科学研究中来。我们希望通过人工智能来加速和推进科学的发展。 David Baker: 我相信蛋白质设计是解决人类面临的许多问题的关键。通过设计具有全新功能的蛋白质,我们可以创造出新的药物、新的材料和新的技术。人工智能为我们提供了前所未有的能力来设计蛋白质,并为世界带来积极的改变。

Deep Dive

Chapters
The accuracy of AI protein prediction is crucial for scientific research. While AlphaFold2 isn't perfect, its confidence scores help scientists assess the reliability of its structural predictions. The model's user-friendliness and open access have greatly accelerated research across various fields.
  • AlphaFold2's accuracy isn't 100%
  • It provides confidence scores for its predictions
  • User-friendly and open access, accelerating research

Shownotes Transcript

As artificial intelligence seeps into some realms of society, it rushes into others. One area it's making a big difference is protein science — as in the "building blocks of life,"* *proteins! Producer Berly McCoy) talks to host Emily Kwong) about the newest advance in protein science: AlphaFold3, an AI program from Google DeepMind. Plus, they talk about the wider field of AI protein science and why researchers hope it will solve a range of problems, from disease to the climate.*Have other aspects of AI you want us to cover? Email us at [email protected]).*Learn more about sponsor message choices: podcastchoices.com/adchoices)NPR Privacy Policy)