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cover of episode Unlocking green hydrogen, and oxygen deprivation as medicine

Unlocking green hydrogen, and oxygen deprivation as medicine

2025/1/23
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Science Magazine Podcast
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Bob Service
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Robert Rogers
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Sarah Crespi
Topics
Sarah Crespi: 我主持了本期科学播客，我们讨论了绿色氢能的生产以及低氧疗法在疾病治疗中的应用。绿色氢气是一种清洁能源，但其生产成本较高。低氧疗法在动物模型中显示出治疗效果，但其在人体中的应用仍需进一步研究。 Bob Service: 我是科学杂志的撰稿人，我撰写了关于绿色氢气生产技术的文章。目前，工业上主要采用化石燃料制氢，而绿色制氢则利用可再生能源电解水制氢。电解槽是关键设备，目前主要有三种类型：碱性水电解槽、质子交换膜电解槽和阴离子交换膜电解槽。改进方向在于降低成本和提高效率。绿色氢气生产成本高，且缺乏完善的储存和运输基础设施，大规模应用仍面临挑战。 Robert Rogers: 我是马萨诸塞州总医院分子生物学博士后研究员，目前在Tectonic Therapeutic公司担任医学主任。我们研究了低氧疗法在疾病治疗中的应用。低氧疗法在动物模型中对线粒体疾病和缺血性损伤有治疗作用，但其在人体中的应用仍需谨慎，需要考虑安全性和递送方式等问题。低氧疗法可能通过影响血红蛋白与氧气的结合来实现治疗效果，未来可能通过药物干预来实现。

Deep Dive

Chapters
This chapter explores the challenges and innovations in green hydrogen production. It discusses the current methods, their limitations, and the advancements in electrolyzer technology aimed at making green hydrogen a more viable and cost-effective alternative to traditional methods.
  • Traditional hydrogen production relies on fossil fuels, resulting in significant emissions.
  • Green hydrogen production uses renewable energy sources like wind and solar power to split water into hydrogen and oxygen.
  • Electrolyzers are the devices used to split water, with various types like alkaline, proton exchange membrane, and anion exchange membrane electrolyzers.
  • Cost and efficiency are major limitations of current electrolyzer technology.
  • There's a long way to go before green hydrogen can meet global energy demands, requiring significant infrastructure development and cost reduction.

Shownotes Transcript

First up this week, although long touted as a green fuel, the traditional approach to hydrogen production is not very sustainable. Staff writer Robert F. Service joins producer Meagan Cantwell to discuss how researchers are aiming to improve electrolyzers)—devices that split water into hydrogen and oxygen—with more efficient and durable designs.

 

Next, Robert Rogers), who was a postdoctoral fellow in molecular biology at Massachusetts General Hospital when this work was conducted, talks with host Sarah Crespi about the idea of chronic hypoxia as medicine). Efficacious in mouse disease models, the big question now is whether long-lasting reduced oxygen could help people with certain serious conditions, such as mitochondrial defects or brain inflammation. The pair discuss what we know so far about this potential treatment and the challenges of delivering low levels of oxygen around the clock.

 

This week’s episode was produced with help from Podigy).

 

About the Science Podcast)

 

Authors: Sarah Crespi; Meagan Cantwell; Robert Service