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🏥 NHS to Launch World’s Biggest Trial of AI Breast Cancer Diagnosis

2025/2/5
logo of podcast AI Unraveled: Latest AI News & Trends, GPT, ChatGPT, Gemini, Generative AI, LLMs, Prompting

AI Unraveled: Latest AI News & Trends, GPT, ChatGPT, Gemini, Generative AI, LLMs, Prompting

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专注于电动车和能源领域的播客主持人和内容创作者。
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主持人: 我认为这项试验最有趣的地方在于,他们不是只使用一套AI系统,而是测试了五套不同的系统,每套系统都有其独特的方法。这项试验规模巨大,涉及英国30个乳腺癌筛查中心,资金高达1100万英镑,是英国政府癌症计划的关键部分。试验将462,000张乳腺X光照片用AI分析,另外238,000张则由两位放射科医生以传统方式解读,以比较AI与人类专家的诊断结果。AI的目标不是取代放射科医生,而是辅助他们,成为他们的额外工具,从而提高效率。AI在医疗保健中的潜力巨大,因为它可以帮助解决放射科医生短缺的问题,并确保患者能够快速准确地得到诊断。 嘉宾: AI系统通过学习大量的乳腺X光照片(一部分有癌,一部分没有癌)来学习识别癌症模式。AI系统使用不同的方法,例如深度学习(模拟人脑学习方式)等,来分析乳腺X光照片。使用AI进行乳腺癌检测的主要优势之一是速度更快,患者可以更快地获得结果,减少焦虑,并可能导致更早的治疗。AI的另一个好处是一致性,它不会疲劳或分心,可以始终如一地分析图像,减少错误,确保即使是细微的癌症迹象也能被检测到。AI还可以帮助解决放射科医生短缺的问题,使他们能够专注于更复杂的情况或花更多时间与患者相处。AI系统容易受到数据偏差的影响,如果训练数据有偏差或不完整,AI系统可能会延续这些偏差,因此确保数据的多样性和代表性至关重要。过度依赖AI是一种风险,AI只是一个工具,它有局限性,人类专家仍然需要审查AI的发现并做出最终决定。AI系统的透明度很重要,我们需要理解AI系统的工作原理,并对其结果有信心。未来几年,AI将在医疗保健中得到更广泛的应用,例如图像分析、诊断、治疗规划等,并可能扩展到药物研发、个性化医疗和疾病预测等领域。我们需要讨论AI在医疗保健中的伦理问题,并确保AI不会加剧现有的不平等。AI是一个工具,可以用于善或恶,我们社会需要决定如何使用这项技术,并确保它造福于所有人。AI系统需要高质量且具有代表性的训练数据,以确保其准确性和公平性。如果训练数据缺乏多样性,可能会导致对某些人群的诊断不准确,这会违背使用AI实现更公平医疗保健的初衷。数据隐私和安全对于AI系统至关重要,需要采取措施防止未经授权的访问或滥用数据。关于在医疗保健中完全信任机器做出重大健康决策的问题,存在不同的观点,需要在人类专业知识和人工智能之间找到平衡。AI可能会改变医疗保健工作者的工作,而不是消除他们的工作,它可能创造新的机会或改变现有角色的重点。AI可以作为医疗保健专业人员的高技能助手,使他们能够专注于自己最擅长的事情。为了有效地利用AI,需要对医疗保健专业人员进行教育和培训,使他们为AI时代做好准备。需要考虑AI对医疗保健系统更广泛的社会影响,包括医疗保健的可及性、成本和整体质量。AI可以帮助改善医疗保健的可及性,但如果AI驱动的医疗保健的获取受到成本或居住地等因素的限制,也可能加剧现有的不平等。AI在医疗保健中的未来不是一成不变的,而是我们通过所做的选择来创造的,因此我们需要保持知情,参与关于这项技术的伦理讨论,并要求开发和实践这项技术的人员保持透明。

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The UK's NHS is launching the world's largest trial of AI in breast cancer screening, using five different AI systems to analyze 700,000 mammograms. This ambitious project aims to improve diagnostic accuracy and reduce waiting times, potentially revolutionizing breast cancer detection globally. The results are expected in a few years.
  • NHS initiates world's largest AI-assisted breast cancer screening trial
  • Trial involves five different AI systems and 700,000 mammograms
  • Aims to improve diagnostic accuracy and reduce waiting times
  • Funded by the National Institute for Health and Care Research

Shownotes Transcript

Translations:
中文

All right, let's dive into this. AI and breast cancer detection. Pretty fascinating stuff. Yeah, for sure. You sent over this article from The Guardian about this huge NHS trial using AI to analyze mammograms. Right. And it's, get this, the world's biggest trial of its kind. Wow, that's big. 700,000 mammograms. Yeah.

It's certainly ambitious. What I think is interesting is that they're not just using one AI system. Oh, really? They're testing five different ones, each with its own unique approach. Oh, wow. Okay, so five different AI systems going head to head to see if they can detect breast cancer as effectively as, you know, the traditional double reading system.

By radiologists. Yeah, it's quite a competition. Yeah, high stakes. The stakes are incredibly high, not just for the companies that are making these systems, but for, I mean, healthcare itself. Like if this works, it could change everything. Yeah, that's huge. So this is happening across 30 different breast cancer screening centers in England, right? Yeah, that's right. And it's funded to the tune of 11 million pounds. Wow. By the National Institute for Health and Care Research.

So they're putting some serious money behind this. Yeah, absolutely. And this trial is a key part of the UK government's new cancer plan, which aims to make Britain a global leader in, well, cancer care. I see. OK. So how does this AI stuff actually work? I know it involves mammograms, but...

What's the process? Sure. So imagine you're trying to teach a computer to see. Okay. But instead of showing it like, you know, pictures of cats and dogs, you give it thousands and thousands of mammograms. I see. Some with cancer, some without. So it's like the AI is learning from this giant library of images. That's right. It uses this thing called machine learning to pick up on images.

Tiny little patterns, things that might mean cancer, things that even really experienced radiologists might miss. Wow. Okay. So what kinds of AI systems are being used here? Are they all using the same method? Oh, no, not at all. Some of these systems are based on what's called deep learning, which it uses these artificial neural networks to try to mimic

how the human brain learns. Oh, wow. So you're giving the AI a little brain of its own. You could say that. Others, they might use different techniques, each with its own pros and cons. So the trial is designed to compare these different approaches and see which ones do the best job.

This is getting really interesting. Five different AI systems, all with different ways of analyzing mammograms. Yeah. So what happens next? Like, how do they test these systems? Well, they're going to analyze about 462,000 mammograms using AI. Okay. And the other 238,000 will be read the traditional way by two radiologists. So they've got this control group, basically. Exactly. To see how the AI stacks up against the...

You know the gold standard the human experts. That's right And then they're gonna compare the results right see how well the AI did did it detect the same cancers? Right. Did it miss any that the radiologists caught? Did it flag any false positives? Wow, it's like a Competition but with life or death on the line. Yeah, it is and it's a you know, it's important to remember This isn't happening out of the blue. There's a big shortage of radiologists in the NHS and

And it's it's only going to get worse. Right. Article mentioned a projected 40 percent shortfall by 2028. Yeah, it's a scary thought. And that's why that's why the potential of AI is so, so exciting. If it's safe and it works, it could really help the NHS and make sure patients get diagnoses quickly and accurately. So it's not about, you know.

Getting rid of a radiologist completely. Yeah. No, not at all. It's about like helping them, you know, giving them an extra tool. Exactly. It's about using technology to make humans better at what they do. Yeah, that's a good point. Because I think a lot of people hear AI in healthcare and they think, oh no, the robots are taking over. Yeah, I understand that. But that's...

That's not the point here. It's more about working together. Yeah, collaboration. Exactly. So you have these AI systems training on tons of data, learning to spot cancer. You have the control group with the human experts. What's next? How long until we get the results of this big showdown?

Well, we're going to have to wait. The trial isn't expected to have results for a few years. Analyzing all that data takes time, and we have to make sure the results are statistically sound. That makes sense. But in the meantime, there's a lot to be excited about.

This trial could really change how we approach breast cancer detection. Definitely. And it could lead to even more new and innovative ways to use AI in healthcare. Yeah, that's true. Okay, before we get carried away with the future, let's talk about the potential benefits of AI in this particular situation. What are the main advantages of using AI for cancer?

Breast cancer detection. Well, I think one of the most obvious ones is speed. AI can analyze images much, much faster than a human can. So patients could get their results faster. That makes a huge difference. Yeah. Less waiting, less anxiety. And potentially, you know, it could lead to earlier treatment if it's needed. Yeah. Anything that speeds up the process is a good thing in my book.

What else? Well, another benefit is consistency. Okay. AI systems don't get tired. They don't get distracted. So they can analyze every image with the same level of focus and detail. I see. So that could reduce errors and make sure even tiny little signs of cancer are detected. So it's like having this tireless assistant working with a radiologist. Yeah, you could say that. Making sure nothing gets missed. That's pretty amazing.

Anything else we should think about? Yeah. And as we mentioned before, there's this big shortage of radiologists. AI could really help with that by taking on some of the more basic tasks. So radiologists can focus on the more complicated cases or even spend more time with their patients. So it's not just about replacing humans. It's about working smarter. Exactly. Okay. So we've talked about the speed, the consistency, the potential to help with staff shortages. It all sounds good.

But we can't ignore the potential risks, right? Of course not. Any new technology, especially in healthcare, you have to be aware of the downsides. So what are some of the things we should be thinking about? What are the potential risks of using AI to...

analyze mammograms? Well, one concern is that AI is only as good as the data it's trained on. Right. So if the data is biased or incomplete, then the AI system could perpetuate those biases. Okay. So if the AI is only trained on mammograms from, say, you know, one particular group of people, it might not be accurate for other groups. Exactly. And that's why it's so, so important to make sure the data is diverse, like representative of everyone the AI will be used on. Makes sense. Data quality is key. What other risks

should we be aware of? Well, there's also the potential for what I call over-reliance on AI. I see. We can't just assume AI is a magic bullet. It's a tool. Okay. And every tool has its limitations. So we still need the human experts to...

you know, look at the AI's findings, make the final decision. Absolutely. AI should be seen as a way to help human experts, not replace them. Right, right. Okay, so we need to be careful about data bias, avoid depending too much on the technology. Anything else? Yeah, there's also the issue of transparency. AI can be very complex and not always easy to understand. So if it flags a mammogram as, you know, maybe cancerous,

It might not be clear why it made that decision. Exactly. And that can be a problem because it can make it hard to trust the AI. Right. So we need to make sure that these systems are, well, transparent, that we can understand how they work and...

have confidence in their results. Transparency. Yeah, that's important. So we have the potential benefits, the risks, the data quality, the human oversight and the need for transparency. This is complex stuff. There's a lot riding on this. But let's step back for a second and think bigger picture. This trial

It's part of this whole movement toward using AI in healthcare. Where do you see this going in the next, say, 5, 10, 20 years? Oh, it's an exciting time to be in this field. We're just starting to understand what AI can do. In the next few years, I think we'll see it being used more and more to help with things like image analysis, diagnosis, treatment planning, you know, all sorts of things. So kind of like what we're seeing with this mammogram trial, but expanded to other areas of healthcare. That's right.

And as these AI systems get better and more reliable, we'll start to see them doing even more complex things like drug discovery, personalized medicine, even predicting outbreaks of disease. Wow, that's a pretty amazing vision of the future.

But it also brings up some questions. Oh, for sure. Like if AI becomes this powerful tool in health care, how do we make sure it's used ethically? How do we prevent it from making existing inequalities worse? Those are all really good questions. And honestly, there are no easy answers. But the important thing is to have these conversations now before AI becomes so deeply ingrained in health care that it's hard to change course. Yeah, we need to be proactive. Exactly. OK, so for our listeners who are just starting to learn about AI and health care,

What's the one thing you'd like them to take away from this conversation? Well, I think the main takeaway is that AI is a tool. And like any tool, it can be used for good or for bad. So it's up to us as a society to decide how we want to use this technology and make sure it benefits everyone. I think that's a great point. So before we jumped into all the potential benefits, we were talking about the different kinds of AI systems in this trial. Right, yeah. We were discussing AI.

how those systems, some using deep learning, some, you know, other machine learning techniques, how they, uh,

basically learn to recognize the patterns in mammograms that might indicate cancer. Yeah, it's kind of amazing. They're trained on all this data, like you're teaching a computer to to see and interpret these mammograms like a radiologist would. And that brings up a really important point about the data itself. Oh, it's really crucial for the training data to be well, first of all, high quality, of course.

But also it has to be representative, you know, of the of the diverse population that AI is going to be used on. Right. Of course, if the AI only learns from amigrams from, you know, a certain type of person, it might miss important variations or patterns that are present in other groups. Exactly. If the data isn't diverse enough, you could end up with...

inaccurate diagnoses for certain populations, which would defeat the whole purpose of using AI for more equitable health care. Yeah, I see what you mean. So making sure the data is diverse, it's not just a technical detail, it's an ethical consideration. Absolutely. It's fundamental. And beyond just diversity, there's also the issue of data privacy. Right, right. And security. I mean, these systems are dealing with very sensitive medical information. So

So having strong safeguards is really, really important. Yeah, that makes sense. We hear all these stories about data breaches and privacy concerns these days. How can we be sure these AI systems are handling patient data responsibly?

Well, it's a valid concern and one that the researchers and the developers are very much aware of. There are strict regulations and protocols in place to govern how medical data is used and stored. And the AI systems used in healthcare are designed to comply with those standards. So there are measures in place to prevent

unauthorized access or misuse of this data. Yeah, absolutely. Things like data encryption, de-identification techniques, and secure storage systems. These are all ways to protect patient privacy. And importantly, patients, they have the right to know how their data is being used and they can opt out if they have concerns. Transparency and patient control, those are key, right? They are absolutely crucial for building trust. And speaking of trust, one of the biggest questions about AI in healthcare is, well, human oversight. Right.

Can we or even should we fully trust machines to make these big decisions about our health? It's a big question. It's almost a philosophical question, I'd say, about the balance between, you know, human expertise and artificial intelligence. Yeah. Like where do you draw the line? Exactly. And there are different opinions even within the medical community. Some people see AI mainly as a tool, you know, to help radiologists and make them better at what they do, not to replace them.

But others believe that AI could actually surpass human abilities in some areas.

leading to more accurate and more efficient diagnoses. So it's not like a simple yes or no situation. No, no. It's more nuanced than that. It's about finding that right balance. Exactly. The optimal way to combine human intelligence and artificial intelligence. And that balance might be different depending on what you're using AI for, how complex the task is, how much risk is involved. This makes me think about something we touched on earlier.

about the impact on the healthcare workforce. - Right. - If we start using AI systems everywhere, what happens to the radiologists and other healthcare professionals whose jobs might be affected? - Yeah, that's a very valid concern. And it's important to approach this with a lot of thought and careful planning.

AI won't necessarily, you know, eliminate these jobs, but it will likely change them. So instead of getting rid of jobs, AI might actually create new opportunities or change the focus of existing roles. Exactly. Imagine radiologists not having to do all the routine repetitive tasks anymore. They could focus on, you know, the more complicated cases or on research or on spending more time with patients. So it's like AI is like a...

highly skilled assistant, letting the human experts really focus on what they do best. Yeah, that's a great way to put it. And this shift, it could lead to, you know, better diagnoses and better care for patients. It's pretty mind blowing to think about how AI could change the whole health care landscape, not just the technology, but also the

You know, the professional roles and even the patient experience. Yeah, it's a big shift. And as we go through this transition, it's really important to prioritize education and training for healthcare professionals. Oh, right. To get them ready for this new world of AI. Exactly. We need to make sure everyone is equipped to handle the changing demands. So it's not just about, you know, building the technology. It's about making sure the workforce is ready.

ready to use it effectively. Absolutely. And beyond just the workforce, we also have to consider the broader societal impacts. What does AI and healthcare mean for access to care? What about costs, the overall quality of the healthcare system? That's a huge question. It's like AI is this catalyst for a whole chain reaction of changes and challenges. It is. And we need to...

you know, to be thoughtful about this, to look at it from all sides, to recognize both the potential benefits and the potential problems. Yeah, like, for example, AI could help make quality health care more accessible to everyone, even in underserved areas. Right. But it could also make existing inequalities worse if, you know, if access to AI-powered health care is limited by things like cost or, you know,

or where you live. Exactly. That's why it's so crucial to be having these discussions right now to try to anticipate these challenges and make sure that AI is integrated into the health care systems in a way that benefits everybody. It's complicated, but it's also incredibly exciting. It is. We're talking about technology that could completely change health care as we know it. And as we move forward, it's important to remember that this isn't just about the technology itself. It's about people.

Right. It's about making things better for patients, giving healthcare professionals more tools, and creating a healthcare system that's more equitable and accessible for everyone. I think that's a really good point to end on for this part of our deep dive. We've covered a lot, you know, data diversity, privacy, the role of human oversight, the impact on the workforce, and the bigger societal implications. Yeah, it's been a fascinating conversation, and we're really just getting started. We're back, and

You know, it's striking how this whole discussion about AI and breast cancer detection, it feels like we're just scratching the surface. Oh, absolutely. This NHS trial, it's almost like a preview of...

a future where AI is involved in almost everything in health care. It's exciting, but also a little bit overwhelming. Yeah, I get that. We've talked about AI helping with image analysis, diagnosis, but where else do you see this technology going? What's next? Well, one area that's really promising is personalized medicine. Oh, right. Personalized medicine. Imagine

treatments that are tailored not just to your disease, but to your specific genes, your lifestyle, even your environment. Wow, that's taking precision medicine to a whole new level. It is. AI can analyze huge amounts of data like your medical history, your DNA, your habits, and use all that to create a treatment plan that's just for you to make it as effective as possible and minimize any side effects.

It sounds like something out of science fiction, but it's actually happening. It is. And that's just one example. AI could also be huge for drug discovery, you know, helping researchers find new drugs and figure out how well they're going to work. So AI could help us not only personalize the treatments we already have, but also come up with completely new ones. Yeah, exactly. And potentially a lot faster than we can now. And then there's...

preventative care. You know, AI could help us identify potential health problems before they even start by, you know, analyzing your risk factors and things like that. Wow. So it's like having like a personal health advisor constantly keeping an eye on you and helping you stay healthy. Yeah, that's the idea. It's a powerful concept. And we haven't even talked about how AI could make health care more efficient and and less expensive. That's right. We talked about how AI could help with the shortage of health care workers, but it could also

you know, streamline all those administrative tasks, make sure resources are being used well, even help prevent medical errors. Exactly. The potential is huge. But we have to remember that this future isn't guaranteed.

To really make the most of AI in healthcare, we need to be smart about it. We need careful planning, collaboration, and we have to be willing to face those ethical and societal challenges that always come with any big technological change. Yeah, that's true. We can't just jump in without thinking about the potential problems. Right. Like data privacy, algorithmic bias.

the need for human oversight. Absolutely. It's about finding that balance, embracing the innovation, but also making sure it's used in a way that benefits everyone and aligns with our values. So for our listeners, as we wrap up this deep dive, what's the one message you want them to walk away with? What should they be thinking about as they consider this future where AI is playing such a big role in their healthcare? I'd say the most important thing to remember is that

the future of AI in healthcare isn't, it's not set in stone. It's something we're creating right now through the choices we make. So stay informed, get involved in conversations about the ethics of this technology and demand transparency from the people who are developing it and putting it into practice. I think that's a great point. It's a call to action for everyone. Patience,

healthcare professionals, policymakers, everyone involved to work together and make sure AI is used responsibly to create a healthier future for everyone. Exactly. The potential is there, but it's up to us to guide its development and make sure it benefits all of humanity.

Well, on that note, we've reached the end of our deep dive into the world of AI and breast cancer detection. It's been quite a journey. We started with this groundbreaking NHS trial, explored the potential benefits and risks of AI, and even got a glimpse into a future where AI could revolutionize how we think about healthcare.

It's been fascinating, and I hope our listeners have learned a lot from this conversation. So to everyone out there, keep learning, keep asking those tough questions, and keep pushing for a future where technology serves humanity. Until next time, stay curious.