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cover of episode #336 - AMA #68: Fasting, well-balanced diets, alcohol, exercise for busy people, wearables, emotional health, assessing cardiovascular health, and more

#336 - AMA #68: Fasting, well-balanced diets, alcohol, exercise for busy people, wearables, emotional health, assessing cardiovascular health, and more

2025/2/17
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The Peter Attia Drive

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Nick Stenson
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Peter Attia
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Peter Attia: 评估心血管健康需要综合考虑多种因素。首先,深入了解家族史至关重要,包括祖父母、父母、叔叔阿姨等亲属的健康状况和死因,特别是关于心血管疾病、高胆固醇和高血压的用药情况。其次,通过钙化积分(CAC)扫描可以评估动脉的受损程度,尽管该方法存在一定的假阴性率。更高级的评估手段是CT血管造影(CTA),但会增加辐射暴露和静脉染料风险。脂质谱分析也是重要的一环,特别是关注ApoB和Lp(a)的水平,ApoB是所有致动脉粥样硬化蛋白的聚集标志物,而Lp(a)因其高度的致动脉粥样硬化性需要单独评估。此外,血压的监测也不容忽视,理想血压应低于120/80 mmHg。最后,吸烟和代谢不健康(如胰岛素抵抗和2型糖尿病)也是重要的风险因素。我个人不倾向于使用颈动脉内中膜厚度(CIMT)进行评估,因为我认为其提供的价值有限。通过综合这些信息,可以更全面地评估个体的心血管健康风险。

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In this “Ask Me Anything” (AMA) episode, Peter tackles a diverse set of listener-submitted questions, covering a wide range of health and performance topics. He dives into assessing cardiovascular health, discussing key biomarkers and risk factors, and breaks down various fasting approaches, including time-restricted eating and prolonged fasting. The conversation also explores the impact of alcohol on health and disease risk, fundamental principles of nutrition, and optimal protein intake. Additionally, he examines the pros and cons of ketogenic and low-carb diets, strategies for building effective exercise routines, and the role of wearables in tracking health metrics. The episode concludes with insights on emotional health, making this a well-rounded discussion packed with practical takeaways for anyone looking to optimize their well-being.

If you’re not a subscriber and are listening on a podcast player, you’ll only be able to hear a preview of the AMA. If you’re a subscriber, you can now listen to this full episode on your private RSS feed )or our website at the AMA #68 show notes page). If you are not a subscriber, you can learn more about the subscriber benefits here).

We discuss:

  • Episode format: overview of common health topics based on listener questions [1:30];
  • How to accurately assess your cardiovascular health [3:00];
  • The impact of fasting, time-restricted eating, and dietary restriction on metabolic health [9:00];
  • Alcohol: health risks of consumption, limitations of research, and how to weigh the risks against social and personal enjoyment [13:45];
  • Principles of a well-balanced diet: macronutrients, micronutrients, protein, energy balance, and more [23:45];
  • The benefits and drawbacks of ketogenic diets: impact on satiety, metabolic health, athletic performance, lipid levels, and more [29:15];
  • Protein: best sources for muscle growth, total intake, PDCAAS scoring system, and getting adequate amounts on plant-based diets [36:15];
  • Creating an effective fitness routine that fits into a busy schedule [41:45];
  • The role of rest and recovery in a workout routine [46:00];
  • How to track fitness progress beyond just weight on a scale [48:30];
  • The best low-impact exercises for individuals with joint issues [52:00];
  • Wearables: insight vs. compliance, and how to use them effectively [54:45];
  • How to evaluate the risks and benefits of medical interventions: procedural risks, complication rates, and asking informed questions [59:00];
  • Sleep: impact on metabolic and cognitive health, and tips for improving sleep quality [1:03:45];
  • How to identify and address emotional health challenges [1:08:30]; and
  • More.

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