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cover of episode Skin Cancer (The Truth) w/ Dr. Teo Soleymani: Prevention, Detection, and Skin Health

Skin Cancer (The Truth) w/ Dr. Teo Soleymani: Prevention, Detection, and Skin Health

2024/12/2
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Dr. Teo Soleymani
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Mari Llewellyn
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Mari Llewellyn: 我对皮肤癌很担忧,因为我的家族有黑色素瘤病史。我希望了解如何预防和及早发现皮肤癌。 Dr. Teo Soleymani: 皮肤癌并非老年人的专属疾病,年轻人也可能患上致命的皮肤癌,且其病因并非仅仅与日晒有关。许多因素可能导致皮肤癌,例如HPV和环境因素,并非仅仅是日晒。家族病史是皮肤癌的一个重要风险因素,应予以重视。适度享受阳光对身心健康有益,但应避免晒伤。定期自我检查皮肤,并寻求专业人士的帮助,对于早期发现皮肤癌至关重要。一些补充剂可以降低皮肤癌风险,例如烟酰胺和来自亚马逊雨林的补充剂。 Dr. Teo Soleymani: 皮肤是反映身体内部状况的绝佳器官,它能实时告知我们身体的健康状况。皮肤、头发和指甲是相互关联的器官系统,它们都能反映身体内部的压力和健康状况。目前尚无研究表明,每天使用防晒霜可以降低死于皮肤癌的几率。使用防晒霜并不能降低基底细胞癌的发病率。防晒霜可以预防皮肤老化,并降低某些皮肤癌的发病率,但其对生存率的影响尚不明确。美国食品药品监督管理局(FDA)对防晒霜的监管较为严格,这导致了新防晒成分的研发速度较慢。不建议六个月以下的婴儿使用化学防晒霜。近年来,许多最初被认为安全有效的防晒化学成分受到了质疑。研究表明,使用化学防晒霜后,血液中化学物质的含量可能远高于正常水平。矿物防晒霜比化学防晒霜更安全,但使用感可能不如化学防晒霜。选择防晒霜的关键在于使用,而不是选择哪种类型的防晒霜。建议选择矿物防晒霜,例如氧化锌或氧化锌和二氧化钛的组合。应避免使用某些化学防晒成分,例如奥克立林、一些氧苯酮和阿伏苯宗。遮阳、衣物和物理屏障比防晒霜更有效。大多数人都没有正确使用防晒霜。牛脂防晒霜适合用于身体,但不适合用于容易长痘的皮肤。自制防晒霜可能存在配比不准确的问题,建议购买正规产品。阳光照射大约占皮肤早衰的50%,其余50%取决于遗传因素。生活方式、饮食和压力都会影响皮肤的衰老。饮水量不会影响皮肤的水分含量,除非处于严重脱水状态。年轻女性的痤疮可能与荷尔蒙有关,尤其是在下巴和下颌区域。反复使用异维A酸或抗生素可能会导致所谓的“真菌性痤疮”。所谓的“真菌性痤疮”通常可以通过局部药物治疗。清洁皮肤的频率应根据个人肤质而定。经常使用吸管可能会导致嘴唇周围出现皱纹。具有致粉刺性的成分,例如凡士林和一些油类,会堵塞毛孔,引发痤疮。有效的护肤品并不一定昂贵,简单的护肤程序比复杂的护肤程序更有效。基本的护肤程序包括清洁、保湿、防晒和促进皮肤更新。

Deep Dive

Key Insights

Why is the skin an important marker of internal health?

The skin is the only organ that shows real-time changes in response to physical, mental, and psychosocial stressors. It can reflect issues like gut infections, immune dysregulation, and even significant life events like pregnancy or stress.

What are the most common causes of melanoma in young adults?

While melanoma is often associated with sun exposure, many cases in young adults are found in sun-protected areas, suggesting that factors like environmental triggers, diet, and family history play a significant role. Melanoma is the second most common cause of death in women aged 25 to 35.

Why is it important to avoid certain chemical sunscreens?

Chemical sunscreens like avobenzone, oxybenzone, and octocrylene can be absorbed into the bloodstream at high levels, potentially causing endocrine disruption and allergic reactions. Zinc and titanium-based mineral sunscreens are considered safer and more effective for broad-spectrum protection.

Why does sunlight contribute to premature aging?

Sunlight causes UV-related mutations that break down collagen and elastin in the dermis, leading to premature aging. This is similar to how materials like steel and leather degrade when exposed to the sun over time.

How much does diet and water intake affect skin aging?

While drinking water doesn't directly impact skin hydration unless you are clinically dehydred, a healthy diet and lifestyle play a significant role in skin aging. Pro-inflammatory foods can accelerate skin aging, while a balanced diet and stress management can help maintain skin health.

Why do some people experience a 'purge' when using retinoids?

Retinoids speed up skin cell turnover, leading to a temporary flare-up of existing acne. This 'purge' is a sign that the skin is responding to the treatment and can be followed by clearer skin. It typically lasts for about a month.

What are the risks associated with using GLP-1 agonists like Ozempic for weight loss?

GLP-1 agonists can cause significant changes in the skin, hair, and nails, including telogen effluvium (hair loss) and a hollowing in the face. These changes can be persistent and may not revert to baseline even after stopping the medication. However, they can also help with conditions like PCOS, hydradenitis, and psoriasis.

Why is it important to avoid over-cleansing the skin?

Over-cleansing can disrupt the skin's natural barrier and lead to dryness, flakiness, and increased inflammation. While cleansing is important, especially for oily skin, overdoing it can cause more harm than good. It's crucial to understand your skin type and find a balance.

What are the benefits of using retinoids in skincare?

Retinoids are the most effective topicals for skin health. They promote new collagen growth, reduce acne, prevent skin cancer, and improve fine lines and wrinkles. They require time to take effect and are available by prescription, making them more potent than over-the-counter retinol.

How does artificial intelligence play a role in the future of dermatology?

AI has the potential to improve diagnostics and therapeutics in dermatology, making high-quality care more accessible. It can help in early detection of skin cancer and personalized treatment plans, potentially reducing the need for invasive procedures.

Shownotes Transcript

Translations:
中文

If people go through a bad divorce, you know, bad breakup, their hair falls out, their skin doesn't look the same. Women who are pregnant start to get this glow. It's not just a look, it's an actual change in your skin biology. So the skin's an amazing organ that will tell you in real time, oh, something's going on or something is not right, and no other organ can do that. This is the Pursuit of Wellness podcast, and I'm your host, Mari Llewellyn. ♪

Hi guys, welcome back to the Pursuit of Wellness podcast. Today I sit down with Dr. Teo Soleimani to dive into the complex world of skin health, aging, and cancer prevention. I am so happy we did an episode on this. I have melanoma in my family and I'm so happy to be here with Dr. Teo.

It's something I'm aware of, but I really don't know how to avoid it or what I can do. And he was so knowledgeable. We unpack the misconceptions about skin cancer and the role of our skin in reflecting internal health, the surprising effects of diet and lifestyle on skin quality. He shares invaluable advice on sun exposure, the pros and cons of different sunscreens, and the impact of products like melanotan and retinoids on skin health.

We also explore how common issues like acne and premature aging can relate to factors like hormone mimickers and pore clogging ingredients. Whether you're looking to protect your skin or decode your acne journey, this episode is packed with essential tips and insights on taking care of your skin for life. You guys are going to love this episode. It was mind blowing to me and now I feel like I have great tips moving forward with my skin health. So without further ado, let's hop into this episode with Dr. Tao.

Dr. Teo, welcome to the show. Thanks for having me. You have a very impressive resume. Let's see if I can get this correct. You are a Stanford-trained, double-board-certified dermatologist and fellowship-trained skin cancer and facial reconstructive surgeon. Okay.

Sounds better on paper than in real life, but yeah, thank you. No, this is very impressive and I'm so excited to dive really deep on skin today. I've done a few episodes on acne and aging, but I really, really want to discuss...

Plus skin cancer, sun exposure, sunscreen. I think all of us are aware that skin cancer is dangerous and something we should avoid. And I think people are more aware of it now than they used to be. But I still think there's a lot of misconceptions. And I think even I have misconceptions about it. So I really want to dive deep and learn. Totally.

Let's start with just how you became interested in this field. How did you find dermatology? So I had a somewhat of an unusual route, which I realized isn't as unusual as I thought it was. I started in brain surgery. So my training was originally geared towards neurosurgery and

I think it was like I was 28 hours into the hospital and I realized I wanted to have a family more than I wanted to be in the hospital and no knocked any neurosurgeon out there. But it just wasn't conducive to what I saw my life to be. So at the time I decided to make a career change and I,

picked a specialty that would be the furthest from being in the hospital, which became dermatology. And I was fortunate enough to go up to Stanford to do my training. But while I was there, I still got really interested. I always liked cancer biology. I always liked working with my hands. I felt like I was pretty good at surgery. So that kind of resonated and continued in my mindset as to what I wanted to be. But

One thing I noticed going through med school is whenever I'd go to a family event or a gathering, nobody ever came to me and said, hey, what does my liver look like? They would always point to, hey, can you take a look at this? And can you take a look at this? What do you think this growth is? I'm like, you know, I have a lot of derm questions. Why don't I decide on dermatology? And I think it was the best thing that ever happened because it's such a cool organ. And it's probably the last...

specialty in which you can do a lot of things. So I'm very, very lucky to practice what I practice and in the city that I practice. Since you started to now, what have you noticed has changed with skin cancer research?

So the skin's an amazing organ, right? I think it's the only organ that will tell you in real time if something is going on with your body, whether it's your physical health or your mental health or your psychosocial stressors. I think there's an alarming rate of skin cancer in young adults. I see probably in my practice a dozen patients a week that I operate on under the age of 30.

And this wasn't the case even 20 years ago. The adage that this is all a problem of elderly or a problem of aging adult populations is no longer true. And in our generation, people aren't tanning the way they were in the 70s, 80s, 90s. So there's something else we haven't pinpointed yet. And I think eventually there will be a big connection between

environmental factors, diet, gut health, all of these things that will show itself in the coming years. We just, we used to say it's a problem of people who laid out on the beach, which it's still is to a certain extent.

But it doesn't account for my patients who are 18, 19, 20, you know. And in fact, my deadliest forms of skin cancer are usually in young adults in sun protected areas. So that's an area we just don't understand very well. And there's a lot of research being done as to why that is.

So, okay, I'm thinking of Khloe Kardashian as a standout example. And it was kind of cool how she publicized and it was on her face, correct? I think it was really cool how she publicized that. I also just want to touch on

You mentioned the skin is a really cool organ because it's one of the only organs that shows us when something's wrong. And I personally went through a 10-year acne journey that I couldn't figure out, but my skin was repeatedly telling me something's wrong. Totally. And it was just a really interesting experience because obviously it was like awful to have such bad acne for so long. But when I finally got to the reason, it was H. pylori.

My listeners are probably tired of me talking about H. pylori, but I just think it's really interesting because if I had not had the acne, I would not have gone to the extent that I went to to find out what was going on in my gut. So I do think that's a really important point. What would you say are the biggest misconceptions with skin cancer?

So, I mean, before we even hone in on skin cancer, what you mentioned about the skin and being a marker of what's going on inside is 100% true. I mean, just the simplest thing, like kids in college during finals. And when we talk about skin, we've got to talk about hair and nails because they're all connected. They're the same organ system. Kids in finals will come to my practice with their hair falling out in clumps. The hair is an excellent biosensor of all the stresses in your body.

People who have gut infections, exactly like what you mentioned. I have a patient right now who's a very close family friend who has been dealing with very refractory hives, head to toe.

And H. pylori was one of the culprits. So there's a huge connection between the gut microbiome, the gut immune system and then the skin's response to it. So it's all about kind of immune homeostasis and well-being. You know, if people go through a bad divorce, you know, bad breakup, their hair falls out, their skin doesn't look the same.

Women who are pregnant start to get this glow. It's not just a look, it's an actual change in your skin biology. So the skin's an amazing organ that will tell you in real time, oh, something's going on or something is not right. And no other organ can do that. In regards to skin cancer, I think

There's a lot of misconceptions. One, it's not a problem of the elderly. In fact, most of my patients who die of melanoma, which is historically our deadliest form of skin cancer, are young adults. It's the second most common cause of death in women ages 25 to 35. But nobody ever talks about that. It's not just sun-related. I get this misconception all the time.

The majority of melanomas that I see in young adults are in sun protected areas. There's other causes, things like HPV, things like environmental triggers, like people who drink from well water. So why I bring this up is unfortunately in dermatology, there's a lot of fear mongering and I don't want to say fear mongering, but there's a lot of, there's this sense of making people feel guilty that they brought this upon themselves or they did this. That one time you went to the beach, you didn't wear sunscreen. That's the cause. And it's not true.

I enjoy the sun, I'm a skin cancer surgeon, I'm outside with my kids all the time.

Do I burn? No, I try not to. But I also know that's not the only culprit. Probably the biggest thing that people don't look at is just your family history. If you have a strong family history, maybe you should take some additional forms of protection. If you don't have a strong family history, maybe your genetics tolerates a little bit more UV exposure and other things. But definitely misconceptions are young adults are not implicated. That's not true. Sun is the only cause. That's not true. Okay.

So those extra measures, I'm kind of coming from a personal standpoint here and I'm hoping people listening can relate. My mom had melanoma and had to have it removed on her back. And like you said, she blamed herself because she was like, oh, I used to, she lived in Portugal as a kid. She was like, I used to lay out on the tinfoil thing with the oil. And, you know, I think she did probably lay out in the sun too much, but-

There definitely is some like shame connected with it. And I went through a phase and I'm going to put my hands up and say I went to tanning beds probably for a year straight in college. I've done it. Ugh. I've done it. It's my biggest regret. We didn't know any better. I went to college and everyone there was from New Jersey. Everyone did it.

And I was like, oh, I guess. And everybody wants to be tan. Yeah. And I'm from the UK. I'm not a tan person. So I was like, this makes me look better. I'm going to go. But now I'm pretty paranoid about melanoma. So I go to the dermatologist. I get full body skin checks. What other things should I be doing to catch it early if I get it?

So more likely than not, your mom's melanoma was probably not purely driven from the sun because it was on her back. If it was purely sun-related, usually we see it on the head and neck or areas of chronic sun damage. So that's one. What is worrisome is usually those melanomas have a strong hereditary component. You have probably an increased susceptibility, so you're doing all the right things. Okay.

Obviously, don't burn when you're out in the sun, but you can enjoy the sun. There's a component of being outdoors that makes you feel well that translates into actual physical wellness. So if you're outside, you're being healthy, you're being active, that gives you a sense of wellness and health that I can't measure in a test tube per se, but you're obviously healthier, so it's good for your overall well-being.

Additional things that you can do aside from surveillance, aside from sunscreen, there are supplements that reduce your skin cancer risk. I like nicotinamide. It's a supplement that's been shown to reduce your non-melanoma skin cancer risk by up to 30%. There is a supplement called polypodium leucotomus, which is from a fern in the Amazon rainforest.

that you can take that will reduce your chance of burning while being out in the sun. So you can be outside longer before you need to apply or reapply. I personally take a product called sun powder that has all that in that something I formulated originally for my patients, but just being somebody based in Los Angeles, it, you know, sun is 24 hours, 365 days a year. So it's sometimes impossible to protect yourself or reapply for swimming, surfing, things like that. Yeah. Aside from that,

Being proactive is the number one thing you can do. Surveying your own skin. You go to the dermatologist maybe once a year, maybe twice a year, right? That's two time intervals.

Simple exams, looking at your skin, having a significant other or somebody that can help you out, survey your skin is really, really powerful. Early detection, just like any other cancer, whether we're talking about breast, colon, prostate, skin, early detection is what dictates good outcomes. So one, the guilting thing sucks. Your mom didn't do it to herself. And even if she did have some son, it was in an era where we didn't know any better. Yeah.

Number two, I think if you catch it early, and hopefully she did, the outcomes are phenomenal. Now, some people, unfortunately, will succumb to skin cancer. It's just a dark reality that we have. But unlike looking at your lungs or looking at your liver or looking at any other organ system where you can't really see it, the skin will tell you right away, hey, something's here that shouldn't be here. So just being proactive is really, really important. ♪

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Byte is offering our listeners 20% off your first order. Go to trybyte.com slash pow or use code pow at checkout to claim this deal. That's T-R-Y-B-I-T-E dot com slash pow. You mentioned the fatality rate of melanoma, which obviously is like a dark topic, but just to, I guess from my own ignorance, I don't understand if someone has melanoma and

and it's bad, is that because they didn't catch it early enough? Like how do you determine when it's bad? And then do they go through the same treatments as someone with regular cancer? Do they do chemo? Great question. So when we talk about skin cancer, there's generally three main forms. There's basal cell carcinoma, squamous cell carcinoma, and melanoma. For every one melanoma, melanoma has been historically our deadliest form, but it's also one of the more rarer forms.

So for every one melanoma, there's 10 of the non-melanomas. So in the United States alone, about one in four Americans will develop either a basal cell or a squamous cell carcinoma. Okay. Melanoma, the average number of patients that dies, one every 52 minutes in the United States. Nobody ever talks about that. Now, the good news is that trend is, it's downtrending.

partly because of the development of what's called immunotherapy. It won the Nobel Prize in 2018 in the way we treat cancer. And it started from skin. And now we use it for every cancer under the sun, colon, breast, lung, kidney, you name it. But it changed the way we treat patients with melanoma. And the good news is, you know, we see the death rates decreasing more and more.

Is it because we didn't catch it early? Partly, but there are some melanomas that are just really unfortunately bad players. They just, you know, from the time they start to the time they spread throughout the body can be as short as a month.

Now, importantly, melanomas fall in second in line in the United States to skin cancer deaths. The number one thing has become squamous cell carcinomas, and people don't talk about that either, but that's about a death every 40 minutes in the US. Wow. And that's much more heavily sun-related, but fortunately not a problem of young adults. It is something that is chronic and requires a lot of accumulations of sun damage for it to develop. So usually you can pick that up

before it's too late, unlike sometimes melanoma. There's been a lot of very well-known celebrities, very well-known athletes that are dealing with melanoma, including metastatic melanoma. So everybody from Bob Marley to Jimmy Carter, Bob Marley famously passed away from melanoma and Jimmy Carter is kept alive because of those immunotherapies. So

a lot to unveil in the skin world. And I don't want to bring fear into people's minds, but it's an easy organ to check. So just get it checked. When you check your own skin, I think something that I get confused about is what...

constitutes as melanoma? Like how do you know? Does it always look like a weird shape or like what should you look for? Simplest things. There's all these like rules, the ABCDs, etc. The simplest things is if you have a growth that doesn't heal in a month, the one month is a cutoff between something that was like a pimple or a bug bite or an ingrown hair to something that should

Probably be checked. Okay. So if you develop something that doesn't heal in a month, if you develop something that bleeds easily,

Those are the first two signs of skin cancer. Now for melanoma, melanoma historically has been what looks like an ugly mole. So when we talk about moles, finding a melanoma is like playing Where's Waldo, right? You have a field of normal moles and you're looking for that bad player. The things that you want to look out for historically have been the ABCDs that we talked about. So if you have a mole that's kind of asymmetric, right?

You can't fold it upon itself evenly. If you have a mold that has multiple colors, if you have a mold that has irregular borders, if you have a mold that's large, so we say a number two pencil tip eraser. But my biggest one is the E, which isn't even in the ABCDs, is evolution. So if your mold is changing, you have a new growth that wasn't there before, you have

something that was stable and is now changing shape or color, you should get that checked. Now, young adults can develop new things up until around age 35 to 40. But that doesn't mean you get a carte blanche to say, oh, hey, that doc said up until 40, I can make new things. But generally, our skin is a little more dynamic. And then after around 35 to 40, we shouldn't really be making new moles. So anything new, there's that evolution part, should be checked.

What is a mole? Like, why, what are they? That's a great question. A mole... I've never thought about that until right now. I don't know if I've ever been asked that. So a mole is a collection of cells called nevis cells. And they are like...

The cells that kind of produce the color in our skin, they're a derivative of those cell lines that cluster together in the skin. So they usually look as like a brown bump that's been there since childhood or early adulthood. And they tend to be hereditary as well. So if mom or dad was moley, you may be moley. What's important to know is that almost 90% of melanomas don't arise in an existing mole. They arise in normal skin.

Why we make a big stink about moles is that melanomas look like moles. So only 10% arise in existing moles. That's why being proactive, having somebody look at your skin and say, okay, I remember that mole on the shoulder. That's always been there. I remember that mole on the belly. That's always been there.

And then looking for change over time, hey, that one on the upper back wasn't there before. What is that? That's how you detect it. So there's the where's Waldo game to play. But moles are usually just a beauty mark. You know, the most famous one I think of is Cindy Crawford's on her upper lip. Yep, yep. They're meaningless. They're just part of your normal skin biology.

I always thought it happened to existing moles. I don't know why I thought that. A lot of people think that. Almost 90% of melanomas arise in normal skin. Have you heard of this stuff? I don't know the scientific name for it, but I remember there was a kind of phase of it being popular when I was in college of melanotan. Oh, yeah. Do you know what that is? Yeah, yeah. So melanotan and melanotan-2, which it's come back, is this...

hormone mimicker that mimics a hormone that's released from our pituitary that increases the amount of cells that produce our skin's color. So women and men snort this. Snort? Yeah, they snort it. It's a spray. They spray it up their nose. It used to be a pill. It wasn't very effective. Then they made an injection, but it wasn't very effective. So the quickest way to your pituitary, which is right

right? Like sitting in the center of your forehead area is through the nose. So they snort this artificial hormone.

in hopes to stimulate the brain to release more of the natural hormone to produce our skin's color. To be more tan. Yeah, to be more tan. Is that sketchy? There's a lot of problems. I mean, I wouldn't start anything to begin with, let alone something to tan you. I mean, there's easier ways, just put on spray tan. Yeah. There's a lot of consequences because it mimics a few other hormones that are really important in blood pressure control, really important in salt management and hydration status. So those often overlap.

And we've seen a lot of consequences in young adults, especially in Australia and a little bit in Northern Europe countries, Northern European countries where patients have had bad outcomes. Now there's been a couple reported cases of melanoma developing from them. I don't know how often they used it, but you can theorize if you're snorting this stuff a lot, your body just doesn't know when to tell the skin cells to stop growing and they

turn bad but I just I wouldn't recommend snorting anything for yeah that sounds really sketchy honestly it's just crazy but I mean people do anything to be tan I listen I can relate like I I love to be tan but I went through a major spray tan phase now I put self-tanner on maybe it's not the best thing ever for my skin but like you know you know what's interesting I

I see this a lot. Patients who are tan come to my office asking to get lighter. No. And patients who are from fair-skinned ethnicities, fair-skinned countries, always want to look tanner. We always want what we can't have. The grass is always greener. 100%. And the stuff we try to do is just crazy. I know.

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So sunscreen. Yeah. I feel like this is very debated slash controversial. 100%. Crazy. I've had different guests on the show. There's this trend of carnivore lifestyles, and I feel like those people tend to be more

Sun exposure, no sunscreen. They just put tallow on their skin. That's like a movement right now. I know. Of people who don't believe in sun protection. But then I have skin experts on the show who are super pro sunscreen. Which camp do you fall in? Okay. A lot to talk about here. Yeah. So,

In my practice and in the area of practice, I see a lot of complex and high-risk skin cancers. I've developed a reputation for treating some of the worst and the worst in Los Angeles. There's a lot of things about sunscreen that should be considered true and a lot of things that should be questioned. So first and foremost, and I'm going to get a lot of heat for this, I know it,

There has not been a single study to date that shows that if you diligently put on sunscreen every day, it decreases your chances of dying from skin cancer. That's number one. Number two, the most common form of skin cancer, which is basal cell carcinoma, almost one in three Americans, fair-skinned individuals, will develop it.

In every single study we've looked at diligent sunscreen use versus no or minimal sunscreen use, there has not been a change in the incidence of basal cell carcinomas developing on sun-exposed skin. Wow.

Why do we push for sunscreen? There's two reasons. One, we know it protects against premature aging. So if you just want to look good, you want to protect yourself from looking like a wrinkled leather bag, you should wear some sunscreen. Number two, it does decrease the incidence of some garden variety skin cancers, namely some melanomas and some squamous cell carcinomas. But the jury is not out yet as to whether that makes a difference in survival. That's a totally different thing. Now,

Sunscreen is a regulated drug in the United States. It's considered an over-the-counter non-prescription drug, so the FDA regulates it, unlike other countries. So the US is a little bit slow in putting out new compounds that will provide sun protection. There's been a lot of discussion over the past five years about chemical sunscreens and what they do to our bodies.

Before we even dive down that way, that path, we know for babies, six months and younger, historically, the stance from the American Academy of Pediatrics and the American Academy of Dermatology is that we don't recommend chemical sunscreens for babies because baby skin act like mucous membranes, like the inside lining of our mouth, and they absorb what you put on. So for the past 20 years, we've not recommended chemical sunscreens for babies. Now,

In the original FDA approval for sunscreens that came out in 1999, there was about 19 chemicals that we had originally considered generally safe and effective. All that's changed in the last three years. The majority of those chemicals are now questioned to be no longer generally recognized as safe and effective.

There was a really publicized study that came out two years ago that showed that with even one application of a chemical sunscreen,

When we drew patients' blood, you can see that chemical at 500 times the upper limit of what's accepted as normal. So there's a lot of data and a lot of people questioning, what the hell are we doing? What are we putting on our skin? Do I wear sunscreen? Yeah. Do I forget to apply it? Yeah. Am I a typical guy with kids? Yeah. So...

I tend to like mineral sunscreens better. Not that I'm against chemical sunscreens, but there is enough smoldering data questioning the safety of some chemical compounds as endocrine disruptors, hormone mimickers,

And very minimal to no data for the minerals. So if I have to pick between the two, I'll just pick the mineral. Now, I know the application under makeup, the feel, the grittiness all play a big role as to whether you're going to use it or not. You know, the simplest recommendation I get in my office, they're like, what sunscreen are you going to use? I say, whatever you're going to put on because it's going to be a glorified paperweight if you buy it and you don't use it. Yeah.

If I were to pick though, I pick mineral sunscreens. I like zinc or zinc and titanium. They do provide better broad spectrum coverage. They last longer. There's no endocrine or chemical mimicker of our body's messaging molecules. But if you're not going to wear it, I think chemical sunscreens are okay. There are a few that I would avoid.

like octocrylene, some of the oxybenzones, avobenzones. I tend to avoid those. Not only are they maybe problematic, they're well-known contact allergens too. My wife has an allergy to all the avobenzones and cinnamates. She is an intense one to octocrylene. Yeah. So octocrylene is notorious. It's actually banned in Europe because the breakdown product of octocrylene in the sun is benzophenone.

which is a well-known carcinogen. -That's insane. -Yeah, I know. And we considered it safe and effective because we thought that when you smeared it on your body, nothing would happen until that study came out showing, "Oh shit, we can detect it in the blood at way higher levels." Now, the other thing is we didn't have sunscreens, really effective ones 25 years ago. Now that we have them and there's a lot of pushing for them, people start using them at a younger age. Let's say you start at 18.

By the time you're 58 or 68, that's 50 years of daily application of something. Yeah. Surely there's got to be something that's going to go awry in some patients, maybe not all, maybe a small subset. The other thing that I found is that shade, and not found, I mean, the evidence points to it, shade, clothing, physical barriers will always outperform anything you smear on your skin.

The majority of the United States doesn't even apply the right amount. I mean, you've got to put a shot glass of sunscreen on to be adequate. And I don't do that most of the time. And I should know better. I'm in a rush usually. My kids are running around. I'm like, let me just not burn. Let me get out there and take care of them. So there's a lot of variables to sunscreen. Do I think you should wear it? Absolutely. Do I think it's the only way to protect yourself? No. Do I think there's good ones? Totally. Do I think there are bad ones? Totally.

I don't want to get you in trouble. No, no trouble. Can we say like what brands should we avoid completely? I don't know about brands because there's so many brands out there all the time. I tend to avoid chemical sunscreen. So when you look on the back and if you go to a store, about 90% of the sunscreen is available, readily available at pharmacies, places like Sephora, you know,

Ulta Beauty, whatever, are chemical sunscreens. What's the chemical? So there's Avobenzone, Oxybenzone, Octocrylene, several other chemical sunscreens. Those are the three most common ones that I see. What you want to look for is zinc or zinc and titanium. Okay.

A lot of the products that are made to go on really nicely, a little more elegantly, tend to have chemicals or chemical boosters for that feel. Zinc and titanium, unfortunately, can feel a little gritty. Okay. Have you heard of the brand Solensky? Is that what it's called? Yeah. Yeah.

I don't think I have. Okay, it's new. And I'm curious what you think about it. I'll show you afterwards. But it's new beef tallow zinc. Interesting. Very simple sunscreen. And I'm curious what you... I would put it on my body. I'm scared to put tallow on my face. So I'll tell you a few things. I'm fine with putting tallow on so long as you don't have acne. See, yeah, I'm so acne prone. I think...

tallow is fine as a as a mediator it behaves almost the same way as petrolatum like vaseline or aquaphor you can't put it on acne prone skin it clogs your pores you break out yeah if you don't have that history i'm fine with it what is more important to me is the active ingredient so zinc is great i mean people formulate their own sunscreens at home the problem with that is

Having a good sunscreen requires some actual science. You have to check what's called the minimal erythema dose, or simply put, how red your skin gets in a certain amount of time. So to be able to test for that is not that easy. And most of the time when people are formulating things at home, it's not a perfect science. So they're either putting not enough active ingredient, incorrect formulations of active ingredients, so you don't get the coverage or protection that you think you should get. Mm-hmm.

That being said, if you're not going to use anything at all versus that, I'd rather you use that. You just can't put tallow on acne prone skin. I can't partake in any of those trends. Yeah, I wouldn't recommend it. But if you tried it and it works, no problem. I don't see a harm to it.

I think I'm open to ideas and trends and fads. If it works for certain people, why not? I don't think there should ever be a hard no or yes, except if it's truly a problem. Women, I feel like use, I mean, I'm speaking for myself here, but I think my friends do this too. We use different sunscreen on our face than we do on our bodies. Is that okay? Yeah.

So yes, I think it is because we know that what we consider chronically sun damaged is sun exposed skin. So your face is way more sun damaged than is your abdomen or your mid back unless you live at a beach or live at a nudist colony or something. Yeah, exactly. But even then, you're getting it on your face as well as your body. So your face

We'll always have more UV related mutations than the rest of your body, hands as well. So I think that's totally fine. What is a problem is women who rely on their makeup's sun protection factor. Because again, unless you're applying a heavy load of makeup, you're usually not applying a shot glass worth. Yeah. So the SPF of 15 in your makeup, you're really getting about a seven.

which is the equivalent to my skin type in and of itself. So I wouldn't rely on your makeup. So back to the aging conversation. And I think we covered a lot with skin cancer. I hope we answered a lot of questions there. With the premature aging, how much is the sun impacting that? So I would say, and this is going to get me in trouble again. That's okay. But premature sun is probably 50%. Okay, what makes up the other 50%? Genetics.

Oh, okay. So you can see families, ethnicities that tend to age faster and families and ethnicities that tend not to age as fast. The genetics of certain ethnic skin allows for longer collagen and elastin formation decreases the risk for UV damage. Now we can't control our genetics, right? But what we can control is environmental triggers. So that's where the sun plays a huge role.

And I give this example all the time. You can put a brand new car in the sun and what's stronger than steel, not our skin, and give it 20 years and that steel starts to rust, right? Or you put a beautiful piece of leather in the sun and don't take care of it, that leather will break down and start to wrinkle and crack. Same thing with our skin. So...

As we get a lot of UV accumulated mutations, what happens over time is there's breakdown of our skin's second layer, which is the dermis. That's where all the fun is. That's where collagen is. That's where elastin is. That's where our blood vessels that volumize our skin reside. So UV will break that down over time. So if you want to look good, you should protect yourself from the sun. Now, shouldn't

have beef with the sun, but you should like not burn. You should probably protect yourself from when your skin starts to turn red. Okay. I'm thinking about my husband's mom right now. She's Italian. She's, I don't know, I think she's almost 60 and she looks amazing. But she also is very healthy. Good. Takes care of herself. Yeah. She gets quite brown in the sun, but like she really takes care of herself. How much is...

lifestyle, diet, stress, how much does that impact aging? It impacts everything in the skin. So we kind of knew this for many, many years. And when I trained up at Stanford, we had a really good center for understanding gut, internal immune homeostasis and skin health. There's an incredible connection between immune dysregulation, what we put into our bodies, our gut microbiome and how our skin looks.

So there's a few things. Diet plays an immense role. Why? Because things that are pro-inflammatory to the gut tend to be pro-inflammatory to the skin. And inflammation, whether it's in the skin or in the colon or any other organ system, tends to wreak havoc. So if you're constantly eating a shitty diet, you're constantly...

not doing all the things that you should do to keep inflammation under control, your skin will show that faster. It's a reason why smokers, drinkers tend to age faster. There's a reason why people who are under high periods of stress, namely look at US presidents, there's several aging studies that will show they age much faster than the average matched person. So lifestyle plays a huge, huge role. I mean, and the other thing is it's hard if you do things that

are probably not in the healthy wellness category. They're not isolated activities. So you're not one, generally people are not one to protect themselves from the sun, but also go binge drink and eat shitty food. If you're being sun smart, you're also probably more likely than not watching what you eat, taking care of your body overall. So it's hard to tease out what the actual

thing is that makes the improvement, but they go hand in hand. Yeah. And drinking enough water. 100%. That being said, drinking water does not affect skin hydration status. Oh, really? None. Oh. Zero whatsoever.

except when you're truly clinically dehydrated, which most of the people are not. So we know from a lot of different, very good evidence-based studies, the amount of water that you drink or fluid equivalents does not change the trans epidermal water loss or the amount of water that's being lost in the skin. Only when we're actually clinically dehydrated do we see that in the skin. That's

When you need an IV bag for a rehydration, it doesn't apply to most of us. Okay, got it. But if you're thinking about drinking all your water, you're probably thinking about being sun smart. You're probably thinking about a good diet. So all of those play a role. But if you miss your glass, it won't affect your skin.

You know what I'm thinking of when I had the acne H. pylori situation? The thing that frustrated me the most is I was like, "I'm so healthy." I know. I'm so focused on diet, I drink enough water, I do all the right things. And it was almost like I could see under the acne that I did have good skin, but it was just like this infection almost getting in the way, which I just think it's so interesting. So you probably had-- there's a few things that probably happened.

obviously there's gut immune dysregulation. So there's something triggering your immune system and it's also showing up on the skin. That's number one. Number two, you're young and healthy and very active. So

Young adults, particularly women who are very active, tend to have a hormonal component of acne that's really stubborn. That's what we call the beard distribution or the bottom chin jawline area. And that's just a marker of hormones that are a little bit more sensitive in your skin's response to them. Whether that's aggravated by an infection, that's aggravated by working out and being anabolic in that category, possibly. Yeah.

The other thing that makes it better is we often give antibiotics for acne not because it's an infection but because it regulates the inflammatory response. So in your setting as you cleared the infection, you also helped reduce the inflammation in your skin. So things got a lot better. It hasn't come back since. Good, good. Yeah, I was just going to... Whew!

That's awesome. Yeah. I pray that it never comes back, but it was all here. Like here up, I didn't have anything. It was bizarre. Hormone acne is stubborn, man. It's a really different, it's a different stubborn condition to treat. It's not regular acne. Yeah. It's wild. And I'm noticing, you know, Alex Earl, she has acne under the chin and she said it keeps, I mean, she's been on Accutane four times, I think.

So that may be actually something totally different. Yeah. Which looks like acne, but what we call, I hate this term, it's disgusting, but it's not fungal acne. And it's usually a culprit of being on Accutane or antibiotics repeatedly over time. It clears your skin so that other pathogens that normally aren't there can take residence. Interesting. And it's really frustrating to treat. And I see a lot of young women who are very clean, who

who maybe over-cleanse their skin, have been on repeated bouts of antibiotics or repeated bouts of Accutane with this persistent breakout that's kind of neck, upper chest area. And usually we look for

called pterosporum or we look for a mite called demodexin. Those are usually the two culprits. Once you eradicate it, it's usually gone. Oh, and is that eradicated through medication? Usually topicals, topical prescriptions. If not, sometimes we use oral medications, but usually topicals. When you say overcleansing, what would... Because I feel like I've done that before because it's almost this,

feeling of like, I'm fixing it, I'm fixing it, I'm fixing it. You and I both. Yeah. What would classify as over-cleansing? I don't think there's a fixed answer to that. I think

I tend to get oily. I mean, by mid-afternoon, you can fry a cutlet on my forehead. I'm like, I get greasy. So I feel like I got to clean the oil off so I don't break out. Whereas my wife has very dry skin. She washes her face once a day and she does totally fine. If she overwashes, she starts to get dry and flaky.

In the US and most Western countries, we tend to over cleanse thinking that if we clean the bacteria and grime off, it'll reduce breakouts, inflammatory rashes, eczema, psoriasis, et cetera. But we now know that a lot of that's driven from the inside out. A lot of that's driven from the skin's immune response. So

I don't think we need to over cleanse, but every person needs to know their skin type. I know that if I don't wash my face, at least get the oil off after working out or after a long day in surgery, I'll start to break out next few days. Yeah. So you kind of got to know your skin. This is a completely random question, but something I was just curious about when I was prepping for this discussion, but.

All of us girls are drinking out of Stanley cups, hydro flasks with the straw. Like we've all become straw babies kind of. Are we all going to have wrinkly mouths? It's the same as smokers lines. Yeah. The reason why, well, not almost there. The smoke itself accelerated what we call radial right. It's or smokers lines and lips. Yeah. But it's the same thing. So basically,

repeated person contracts those muscles. Now there's a lot of things that we do now that we didn't have 20, 30 years ago. Neurotoxins, Botox, Dysport, Xeomin that can soften that. There's laser resurfacing that can help soften the line. So we have the tools that our mother's era didn't have. But yeah, if you're really worried about those lines or if you look at a family history and that you have a strong genetic risk for those,

Probably avoid the straws. It just, it makes me drink more water. Me too. I know. I know. Which is crazy. I know. It's like the pros and cons. Do I want to drink more water or not have the wrinkles? I think you can treat the wrinkles. Yeah. You can't treat wellness as easily. You're right. So don't worry about it. Ugh, these cups. I know. It's always two steps forward and half a step sideways. Believe me. Like,

I think we're all drinking out of these cups. I know. I know. It's like a cultural phenomenon. I know. I have like 60 different glass bottles and every time I get a new one, I'm like, this is going to make me do it. And then the end of the day, I'm like, shit, I didn't drink

I didn't drink anything. I know, I go through a lot of those. So a lot of when I talk about skin on this show, we talk a lot about pore-clogging ingredients. What in your mind, what classifies as a pore-clogging ingredient? And what does that do to our skin over time? So anything that is comedogenic, namely things that mimic...

Things that mimic ceramides or are occlusive tend to be pore clogging. Think of things like Vaseline, Aquaphor, Petrolatum, ointment-based products tend to be clogging. Some oils do the same. So what they do is they basically go into the pores and they can't make their way out. So it creates a little incubator of the normal bacteria in our skin to start to grow and cook and then our immune system finds and says, what the hell is going on? That's what a breakout is.

So the first thing you want to do if you tend to have what we call comedonal acne, blackhead, whitehead acne, you want to avoid anything that's comedogenic. So whatever skincare product you're using, the first line you want to see if it's been tested to be non-comedogenic. And most good derm products are. Most cost-effective, over-the-counter stuff have been tested for that.

If you still can't figure out the culprit, oftentimes it's not the product you're putting on. It may be just your activities of daily living that are affecting it. So you get home, you don't wash your face after working out, or you get home, you sleep with your makeup on and you tend to have comedonal acne. It's going to be a problem. Now I know people that swear that I sleep with my makeup on all the time and they do fine. They don't have the predisposition to it. So

There's no one-size-fits-all problem with pore clogging, but more often than not, when you use occlusive, greasy substances, you're going to have a problem. Sleeping in makeup is like my worst fear. It's a disaster. I mean, you shouldn't do it just like... I mean, you take your clothes off to sleep, you should do the same. You should just clean your face. It's disgusting, but...

I'm not judging. And there's other things. I think there are other things that play a big role in that. Once you get past the age of acne, people can apply more occlusive things. In fact, older adults or my mom's era, they can put that. I recommend them to put petrolatum. It's the best moisturizer for their skin. It's the closest thing to our natural ceramides and oils that we can get. But in young adults who have acne,

well-functioning sebaceous glands that are producing oil in and of itself. Now you're competing with each other and that's where you run into problems.

With today's day and age, like on TikTok, I mean there's so many crazy skincare products. The skincare business is insane. I found a brand that I really like and I feel good about as an acne-prone person, but how do we differentiate what's good, what's bad? Should our routine be 10 steps long? I feel like the 10-step long routines are kind of glorified. Yeah, totally. How do we know what to do?

Great question. It gets harder and harder the busier social media gets. I think one, skincare doesn't need to be expensive. That's number one. Actually, there's an inverse relationship between the amount you pay for your skincare and the result of your skin that's over-the-counter products. Procedures, in-office treatments, totally different story. But your skincare should not be expensive. And multi-step procedures...

are always a higher risk for having some sort of problem go awry with either competing ingredients or your skin's response to them. So I have a very simple statement. I call it KISS or Keep It Simple, Stupid. The simpler, the better. You need to wash. If you're oily, get the oil off. If you're not oily, moisturize. And then you need something to protect you from the sun and you need something to turn your skin over.

Oh, that's all fundamental skincare needs to be. Now that's building your, your foundation or building your cake. Everything else on top is like the cherry on top or the frosting, vitamin C and BHA or AHA acids, things like that, or, you know, tweaks once you've gotten your foundations down, but a good washing regimen and product is fundamental.

A good sun protection regimen is fundamental. It doesn't have to necessarily be sunscreen, but that's probably the easiest. And then something that turns the skin over. So the retinoids are the best single thing that you can use for your skin. The brand name used to be Retin-A. Now, you know, brand names have fallen out of favor. So Tretinoin or Adapalene, which are prescription retinoids. They are the only thing in the world that will grow new collagen.

It's the only topical product in the world that will reduce acne, prevent skin cancer, and improve fine lines and wrinkles. Reduce skin cancer? Yeah, absolutely. Okay. Reduce pre-cancers, reduce skin cancers over time. So topicals require work. They require time to take effect, but they've been around for 50 years. They are every dermatologist's best kept secret and friend. And hopefully the word will get out. Now,

When we use the term retinoid, we interchangeably use them with retinol. You'll see a lot of retinol over the counter. Okay. You know, you go to Sephora or Bloomingdale's or wherever and you see retinol. There's an important caveat to that. All retinols are inactive. All over-the-counter retinols are pro-drugs. They cannot be active, so they're made...

to need to convert into the active form. Why is this important? Because prescription retinoids, the effective form, when they're absorbed internally, and this is important to note, topical retinoids are just the cream's versions of Accutane. So not very many people know that, but Accutane is the oral version, and anything topical, retinol, retinoids, tretinoin, adapalene, et cetera, are just the cream versions of that. Okay.

When the retinoid is absorbed, there's some theoretical risk of birth defects that can happen while you are actively using should you get pregnant. That's why they're really heavily controlled by the FDA in making them prescriptions. In the 70s and 80s when Accutane came around, when topical retinoids came around, and we didn't know this, people were sharing pills, people were sharing creams, and some bad things happened.

So we made it really strict to say, hey, this should be controlled by your physician. Well, as you mentioned, the cosmeceutical industry is a multi-billion dollar industry. So they said, shit, there's a lot of money to be made on this. How do we circumvent this? So they came out with an inactive pro-drug form called retinol that allows you to put it over the counter without a prescription. That being said, it's just not as effective as the prescription. So if you're going to use it, both are risky during pregnancy.

Get the prescription form. It's effective. It works better. And stop it should you try to conceive or become pregnant. Okay, because I was literally in my head going to text my esthetician and be like, why am I not on retinoid? But I'm trying to get pregnant, so I should not do that. You shouldn't. Got it, got it, got it. Okay, but my question for you is when I did have...

really bad acne. I tried a retinoid and I swear it made my acne explode. Yes. And I've heard that that happens. Yes. Why? You should be... One, somebody should have told you about that. And number two, we call it the purge or the turnover. So you do... They did tell me that. Yeah. Good. Because you've...

You flare in the first month or so because it speeds up how quickly your skin turns over. So our skin is brand new every 28 days. We have brand new skin every 28 days. When we use a topical retinoid, it increases that speed to every seven days.

So when you have things like blackheads and whiteheads and kind of juicier pimples, they may flare a little bit as the first month goes by. And if you're not worn, people think, this doctor's an idiot. What the hell did he give me? I'm looking worse than when I went into the office. But that's actually a good sign. Okay. That tells us, one, you're responding to the retinoid, and two, clear skin is in the future. Yeah.

So is it pushing things out that may be not visible yet? It can, yeah. It does that. And what it does is it permanently shrinks oil glands. That's why, you know, even if you don't have acne and you have really, you know, you have a heavy sheen or you're very oily, retinoids help reduce that. There's a popular trend in Los Angeles and New York and a lot of

cities where celebrities are is to actually microdose Accutane. I know. Just to keep their skin clear and to help prevent that sheen that is a problem when they're on the red carpet. And I see a lot of patients who ask for microdose Accutane. Really? Yeah. Yeah. That's wild. It prevents breakouts. It's not the right way to do it, but...

It can be done effectively and safely. It's just a little off-label, but yeah. With the rise in Ozempic usage, are you seeing patients come in with hair falling out or changes in their skin? Yeah, the Ozempic face. Yeah. That's a problem, Ozempic, Lingovi. Yeah, so it's funny you say that. Not very many people know this, so I can feel the vulnerability come out. But similar to your story, yeah.

In high school, I used to be very overweight. And somewhere around senior year, I lost about 70 pounds. Wow. I got really into working out and fitness. And in college, I was a total gym bro. You know, that's just what happened. And a lot of it was lifestyle and transformation and, you know, wanting to change my health and my self-esteem, etc. Yeah.

So during that time, I noticed my hair, I lost a lot of my hair and my hair grew back different in a different pattern. I noticed a hollowing in my face. I noticed all the things that you notice with a rapid weight loss. Yeah.

I'm seeing literally the same things I personally went through in all the patients that are on these GLP-1 agonists. And it's really a problem because the first place we tend to lose weight fastest after, especially around age 30, 35 is our face.

And it's an evolutionary protective mechanism. We protect our girdle, assuming we live in hunter-gatherer eras. Our body doesn't like to lose the weight around our pelvis because we don't know when we're going to eat again, but we lose it in our face. It's a frustrating problem because the changes are drastic and they're persistent when you're on the medicine. Limp, lifeless, sheenless hair. Women come and men come in, but men tend not to complain about their hair as much.

come in saying what can i do to improve my hair and so long as you're on the drugs and so long as you're losing weight not much that we can offer besides some small improvements with medication with face fat loss it's become a plastic surgeon's dream because there's a lot of demand for procedures now to re-volumize re-drape resurface all the changes that occur especially around the eyes especially around the cheekbones

Even the color of skin is different. With the amount of weight loss and the desire not to eat, which is what a lot of these medications do, you see this like lackluster color that we used to see in patients who used to be sick or who were in the hospital or who were dealing with major medical illnesses. This loss of turgor in their skin as a result of the drugs. It's hard to treat, but there are things that we can do, especially in the cosmetic world. Do you think it's...

Like just a lack of nutrients? Yeah, that you're not eating. Yeah, right. For sure. You're not eating, you're not drinking. And if you eat or drink a lot, you feel nauseated. Yeah. Totally. I feel like, I mean, when I lost weight, I did lose it rapidly, but I was still eating and getting my nutrients. And I don't think I had...

hair loss or anything like that. So your body was like well equipped to handle it. Yeah. And some people have that sensitivity whereas others don't. That shock loss is called telogen effluvium. My body was very sensitive to it. I mean I lost that in a four month span. Oh wow. It was really fast for a guy. Yeah. And as I

ate again and, you know, gained some muscle and got big at the gym, things kind of returned, but they returned different. And we're seeing that with Ozempic and Wingovi patients. When they stabilize their weight and we see them get off the drug, things don't go back to what they were baseline. They're just inherently changed. Now, we don't know if that's

just accelerated what their body was going to do in the future, or if there's something inherently different about the drug, but they are, their skin, hair, nails permanently look different. Interesting. Yeah. It's crazy. I've also heard that it helps with people who have PCOS and certain like inflammatory issues. Does it help with acne? So it can,

Partly. If your acne is driven because you have PCOS, if your acne is driven because there is some sort of hormone dysregulation,

Or if your acne is driven by your dietary habits, which tend to go hand in hand, patients with PCOS tend to not tolerate sugars very well. They tend to be a little bit more insulin resistant. Yeah. Those patients' acne does get better, partly because they're not consuming a high glycemic index and partly because it helps reduce their body weight, which decreases this insulin resistance. Yep. Usually you see that in the hormone distribution acne, not in the upper half. Yep. But

Totally. I mean, it improves so many things. You know, I see a lot of women with this frustrating condition called hydradenitis, which is like acne of the sweat producing regions under arms, groin area. It's repeated boils. It's really frustrating. Patients tend to be a little bit more overweight who deal with this. And we haven't had great treatments, but as they get their sugars under control with these drugs, their skin disease gets better.

We even see it with psoriasis and eczema. As they get their sugar under control, their psoriasis and eczema improves. Wow. So that's the cool part about these drugs, but the ozempic face kind of sucks. Yeah. That's so interesting. I mean, I'm sure LA is just like... Oh my God. Full of it, right? I get asked to prescribe it every week. And I'm like, probably not the right person to ask. Like, I don't do that. Yeah. And I probably like, I don't condone it, but there's so many places that do it. And

Look, diet's a big problem in the United States. Food quality is a big problem in the United States. Morbid obesity, I mean, we're kind of laughed at by the rest of the world. I think the drugs are great. Are they being overused? Sure. A lot of drugs are being overused. I mean, anything that'll give you a good outcome will be abused in the United States, whether it's

whether it's Accutane, whether it's Ozempic, whether it's any of the stimulant drugs, you know, there's so many things, you know, we live in a culture that wants, if this is good, we want better. Yeah. It's just unfortunately the way of the game. Yeah. No, it's been very interesting to have people come on the show and just hear everyone's opinion on it. I mean...

Like there are some side effects and long-term effects that are concerning, but at the same time, you're right. Like obesity is the number one issue in the US. If it's used well, I think they're awesome. The long-term effects of you dying from a heart attack, stroke, complications from diabetes will far outweigh the rare risks from the drugs. Yeah. It's when...

young, healthy patients who really don't need the drug start to use it, that the body's like, what the hell? What are you doing this for? We're okay. You could change this with lifestyle. But we unfortunately are a pill-popping culture in the country. It's easier to

take an injection or a pill than it is to change your entire lifestyle. And that's like, it's, it's real. That's the hardest part is the mental strength or stamina to be able to tolerate it. And the people that don't have it, you see when they stop the drug rebound right away. Yeah. It's like that with any weight loss journey. I know. I will. It's funny. Cause I've talked about on here, whether I,

Someone has asked me whether I would have taken it back in the day. And I'm so grateful I didn't have the option because I learned so much about, I mean, I wouldn't be here right now. 100%. You know, and I'm sure you feel the same your senior year. 100%. I think that transition was,

it just changes your thinking about things and it's not just your weight, it's your approach to your health, your approach to career goals, your approach to not popping a pimple because you know you want to but you shouldn't. It's not like the single target, it's the change in your outlook. Totally. 100% agree. Yeah, changed my whole identity. Yeah, same. Looking forward with skin cancer, dermatology,

What are you hoping we discover?

I think that, you know, having trained in Silicon Valley, I think I love the idea of artificial intelligence incorporated in healthcare, in diagnostics, in therapeutics. I think that's where the future is. So the need or the accessibility to high quality care is closer than we think. I think kind of, I wish we could revert back a little bit from this

split in opinions. And it's not just in dermatology, it's in everything in the United States. You're either in camp A or camp B and it's blasphemy for a skin cancer surgeon to say you can enjoy the sun. I wish we could kind of revert back a little bit and realize like, hey, we can do all the fun things we want with some caution and certain characteristics. But

I think in the future, if I never have to cut on a face again, that's what I specialize in, unfortunately, is operating on people's faces. I will be very happy. A lot of people, you know, talk to me when I first came out with the idea of sun powder. They're like, what are you doing? I'm like, listen, if I never have to operate on a young or old person's face, if I never have to remove a nose, an entire lip, an ear,

I am happy. My job here is done. So I think that's the future is preventative care. I think the future is AI integration and you're realizing it's not all of, all of it's not in our control. So enjoy it while it can. I think I'm going to start putting a scoop of sun powder in with my greens. I hope it works. I mean, it's amazing. I'm going to, because I'm fair skinned and it's something I'm worried about because it's genetic for me. Totally. And I think

We, when, when we look at these things, I think it's, I think it takes some time when there is a challenge to the dogma, you know, 30 years ago, sunscreen was like crazy. You know, you wanted that copper tone color you want, it was healthy to have a glow and

We shifted this way and saying the sun is horribly bad for us. And now we're shifting a little bit more saying, well, wait a second. I don't know if it's horribly bad for us because there's consequences of not being outside, not getting vitamin D, et cetera. But anything that challenges the dogma, it'll take some time. It's like there's a gray area to everything. Totally. You just follow, figure out what works for you. Yeah. This is the question I ask every single guest. What does wellness mean to you?

It's the ability to be there for my family without having to worry that I will or not. I think a lot changed for me, one, becoming a husband and two, becoming a father, that my perspectives used to be in wellness a lot more self-centered. And now my wellness is

What can I do with my life so that I can take my worries away so I can spend time with my kids and family. And I think it. I don't know if I've ever thought about it like that until now but

wellness changes. It changes a lot. And your meaning 20 years ago to 10 years ago to five years ago is very different. In college, wellness to me meant the most striations in my shoulder muscles and like the leanest weight and the lowest body fat percentage. And then going through med school, it was every student goes through this, not dying from some rare disease because you read about it in a textbook. And then as you get a little bit older and you see like your priorities change, I think wellness is

an ever shifting target, but now it's geared towards somebody else and not me. I think that's beautiful. And I so agree with you. Mine has changed so much since I first started. So really appreciate you coming on. Thank you for having me. Of course. Where can everyone find you online? So, um, I practice in Los Angeles. I have a small social media presence. It's just my name, last name, MD, Teo Soleimani, MD. Uh,

If anybody's interested in Sunpowder, we have a website, sunpowder.co. I think it's an awesome product and evidence-based. We did a lot of clinical trials on the product. But you guys can email me any which way. Almost everybody has my cell phone, so feel free to text me. All my patients have my numbers. Anybody I've ever operated on, my colleagues, everybody has my number.

Fantastic. Thank you so much. Pleasure. Thanks for joining us on the Pursuit of Wellness podcast. To support this show, please rate and review and share with your loved ones. If you want to be reminded of new episodes, click the subscribe button on your preferred podcast or video player. You can sign up for my newsletter to receive my favorites at marilowelland.com. It will be linked in the show notes.

This is a Wellness Lab production produced by Drake Peterson, Fiona Attucks, and Kelly Kyle. This show is edited by Mike Fry and our video is recorded by Luis Vargas. You can also watch the full video of each episode on our YouTube channel at Mari Fitness. Love you, Power Girls and Power Boys. See you next time.

The content of this show is for educational and informational purposes only. It is not a substitute for individual medical and mental health advice and does not constitute a provider patient relationship. As always, talk to your doctor or health team.