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cover of episode Bridging the gap in women's health research, policy and innovation: Kearney

Bridging the gap in women's health research, policy and innovation: Kearney

2025/5/22
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Paula Belostes-Meguerza: 我认为关注女性健康对企业和整体经济都有着积极的影响。然而,目前医疗研究对女性健康的关注严重不足,只有极少比例的研究和药物充分考虑了女性的特殊需求,尤其是在怀孕和哺乳期间。由于资金不足和临床试验中女性代表性不足,导致女性在不健康状态下生活的时间比男性长。解决这些问题不仅能为经济注入活力,更能促进社会公平。女性在家庭健康决策中扮演着关键角色,同时也是医疗保健行业的主力军,因此,改善女性健康至关重要。我们需要增加对女性健康研究的资金投入,改变对女性健康的固有偏见,并制定相关政策,从而真正实现对女性的关怀。

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Women live longer than men, but experience significantly more years of poor health. This disparity is due to several factors, including a lack of research funding, underrepresentation in clinical trials, and gender bias in healthcare. Bridging this gap has the potential to unlock significant economic benefits and improve women's overall well-being.
  • Only 7% of healthcare research focuses on conditions exclusively affecting women
  • Only 5% of available medications have been fully tested for pregnant or breastfeeding women
  • Women live in poor health for 25% more of their lives compared to men
  • Bridging the women's health gap could add $1 trillion to the GDP in 15 years

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Welcome to Meet the Leader, the podcast where top leaders share how they're tackling the world's toughest challenges. In today's episode, we talk to Paula Belostis-Meguerza. She'll talk about what's needed to bridge the gap in women's health and what any leader can do. Subscribe to Meet the Leader on Apple, Spotify, and wherever you get your favorite podcasts. And don't forget to rate and review us. I'm Linda Lucina from the World Economic Forum.

And this is Meet the Leader. Chances are you're going to have some women in your organization and you should absolutely be looking after their health because we firmly believe that it's healthy women, healthy corporations, healthy economy. Only 7% of healthcare research focuses on conditions that exclusively affect women. And only 5% of available medications have been fully monitored, tested or even labeled with the right safety information for women who are pregnant or breastfeeding, given the underfunded

underfunding of women's health and the underrepresentation in clinical trials, it is no surprise that women live in poor health for 25% more of their lives compared to men. Bridging these gaps in understanding, as well as treatment and innovation, can be truly life-changing. In fact, according to a report that the World Economic Forum released last year, bridging the women's health gap can give women seven more healthy days a year.

They could even provide a trillion dollar jolt to GDP in the next 15 years. Paula Belostes-Megherza understands this well. She is the global head of healthcare and life sciences at Kearney, a global consulting firm. She knows the role that things like policy can play in creating incentives for real change, and even in educating leaders, technologists, and those driving clinical trials. She'll also talk to us about what she's learned from W Health,

That's a platform she helped found that's grown into a community of 350 organizations all committed to redesigning health care, sharing best practices, and bridging gender care gaps. She'll talk about what she's learned, as well as her own personal experience with an unexpected health crisis and the fight she undertook to get the treatment she needed. It's a story that drives home the need for improved support for women's mental and physical health.

We'll talk about all that, but first, she'll share more about the women's health gap. There is a really common misconception out there that because women live longer, there isn't a women's health gap. The reality is that even though we live longer, we spend more time in ill health and disability. So it's a little bit of a difference between what we call the lifespan and the healthspan.

And there's a lot of reasons why this is happening. It's because we don't understand the biology of women really well, because we haven't really invested in understanding this biology or looking at the differences between male and female. And the third thing is that there's still a little bit of bias across all parts of the healthcare value chain.

And so let's talk a little bit about the mental health care gap for women, which is even more interesting. So what I would say is if we expand the definition of the mental health gap for women's health, I would talk about brain health overall. And one of the fundamental things that we're starting to understand right now is that the brain physiology and biology of a male and a female are completely different. So that means that we are more prone to develop depression two times as much, the same with anxiety two times as much, and then also

Also, when we think about neurodegenerative disorders like MS or like Alzheimer's disease or dementia, we actually probably represent about 70% of the prevalence of those diseases. So studying the brain of women is going to be a real fundamental unlock for us to live healthier lives and also to live longer. So if we redesigned the healthcare system to tackle all of these issues, the women's healthcare gap, the women's mental healthcare gap, what does the world look like? What's different?

It will be amazing. We're going to unlock some economic opportunity festival. I think a report from the World Economic Forum highlighted that we would inject $1 trillion into the economy. And that is fine, but we need to be led by the fact that it would just all be more equitable. And one of the things that we need to consider as well is that women make 80% of the economic and the health decisions of the family. They're the chief medical officers of the home.

But also in markets like the US, and it is really across the globe, they represent between 70% and 80% of the healthcare workforce. So if women aren't healthy, they're not going to be able to look after other people that are unhealthy to make them better. So just the effects just multiply if we start to think about looking after women. But you asked me, what will it take? So what are the kinds of things that we would want to do practically?

is very multifactorial, the problem, because we've got a lack of funding, like we said. We've got lack of research because women weren't included in clinical trials from 1993. We were excluded because there were some issues that happened with fetal development during a clinical trial in the past.

So we need to get the data. We need to think about women differently when it comes to diagnosis and putting the health around the entirety of the woman, not looking after the hair individual body parts. And we also need to make sure that policymakers and governments are paying attention to this issue. So imagine a world where we really understand the differences in biology between men and women. And we don't think as women, as small men. So imagine if we knew all of that.

we could develop innovations, both from a drug perspective and from a diagnostic perspective that are really tailored to women. So what we call gender precision medicine, the outcomes would be better than women would be looked after from the system in a way that is suited around them. So you wouldn't go to the doctor one day for your cervical smear and another day for your breast examination and another day for your test on your cholesterol. They would look at you in the round and across your life course, whether you are

just in kind of pre-maternal stage, during your maternal stage, or as you're heading into menopause. The other thing, the funding would be flowing because all of the investment banks and the private equity funds would see the economic opportunity. We would have loads of data and I think we would just be a more prosperous and healthier society.

You founded an organization called W Health. Can you tell me a little bit about that? How did it come to be and what is it making possible? So when we started to understand the problem of women's health, we felt that we needed to just bring the collective force of lots of different organizations. So together with a company called Femme Technology and the leader called Oriana Craft, we started to write this open letter about all of the things that needed to be changed to close the women's health gap.

And then we felt, you know when you have a child and you're like in that dark tunnel of, oh my God, I don't know how I'm going to look after this individual. I'm new to all of this. And we always say it takes a village to raise a child. We felt that it was going to take a village to close the women's health gap. So we decided to enlist organizations that would say, we agree with the opportunity, we agree with the challenges, and we agree with the actions that we need to take. And we got 50 of them on board. And then since then, we founded what we're calling W Health because we think that women's health is wealth.

And we are now at 350 organizations that are working on all of the levers that we discussed from investment to data generation, to innovation, to policy and advocacy. Because I think we can achieve so much more together rather than if we go at it individually. And it's very much about leaving the logos at the table and just bringing your passion, bringing your contribution and trying to do a good thing.

So, W Health has launched a special index that helps organizations evaluate how they're doing on closing that gender health gap. Tell us a little bit about this index and why it's so helpful. So, what we felt is that imagine the problem or the opportunity sitting in front of us, and it's a really big elephant, and we need to, the challenge is it

Eat the elephant. Well, where do we start from? Do I start from the tail or the trunk or like the ear or whatever? It's just so massive that we didn't know where to start. And organizations feel like this. A lot of the ones that are partnering with us on this platform say, I want to do something, but I have no idea. Am I already doing good things?

what should I be doing differently? Almost like guide me through this thing. So what we decided was, how about if we first of all assess where is everybody at in those organizations that are contributing and to healthcare delivery in the value chain? So it could be pharmaceutical companies, it could be consumer health companies, medtech companies, investors, healthcare providers and payers. Let's give them a tool where they look at their own operations and they say, okay, this is where I'm doing great and this is where I could be doing better. And then year on year,

get them to see how they've progressed and whether they have moved the needle. And then for all of us to collectively at the overall sector and multi-sector level, see where are we and where are the incremental change that we need to do. And then there's a flip side of the index, which is if you're a very large employer, it doesn't really matter if you're working in oil and gas or if you're a bank.

chances are you're going to have some women in your organization and you should absolutely looking after the health because we firmly believe that is healthy women, healthy corporations, healthy economy. So we're giving them the tools to look at their policies, their benefits, everything that they're doing within the organization to make sure that they are looking after

after the women to make sure that they will reduce absenteeism. We make sure that those women progress in their career because at the end of the day, representation is going to drive representation. And we really believe that we can create a snowball effect of positivity for women and for the economy as well. Are there any best practices that are emerging from all of this that leaders listening to this podcast can say, "Hey, that's really interesting. That's something I have to take forward"?

Yeah. So first of all, we developed it with our advisory board within W Health, who are, again, it's back to the village. It's our village of 30 organizations that are really pushing us to make sure that everything that we're doing is pragmatic, is implementable, and is going to deliver change. So let me give you a couple of examples. So they won't make me saying their name, but we beta tested the employer index with Microsoft. It's a very, very large organization. And they thought that they were pretty advanced in the thinking about this.

And what we found was twofold. One, that it was very patchy. So it was, I'll have a fertility benefit over here and I'll have a menopause benefit over here. But they didn't have the sort of the connective end-to-end thinking of, okay, I've got an employee that might be joining and they might be having trouble with their menstruation. They may have PCOS, they may have endometriosis, which may lead to fertility issues. And then what's going to happen to them when they reach menopause? So that life course approach to the female population was lacking.

And then the other thing that we found is that in these very large global corporations, they have very different approaches in the different countries. So you could find something really cool happening in the UK or something amazing in Japan or something amazing in the US. And it's how can we raise all countries to the same standard and the same level so that we're impacting very large employee populations across the globe.

If we can switch gears now, I want to talk a little bit about burnout and a personal experience that you had with the mental health care gap. Can you talk about that and the turning point that you experienced?

Yeah, I love to tell you about my burnout story. And it's taken a few years to almost look back at it and see it as a positive thing that happened in my life. But it really didn't feel positive at the time. I think it was 2015 or 2016. So again, it's coming up to nearly a decade ago. And I've always been a bit of a people pleaser and always putting my hand up for everything. And then almost like when you're in a meeting and somebody tells you, oh, who would like to take this on? Like without me knowing, my hand would be going out.

And then I ended up at a time when it was a really busy period at work. And one of my colleagues actually went on mental health leave. And I have this sort of like superwoman syndrome of I must save the situation. So I know that he's off and I know that my plate is already very full, but give me his workload and I will deliver for you. And within about three months, I started to get this like really horrific headaches, but I just pushed through and pushed through and pushed through. And I knew that physically I was getting to the limit.

So then just one day I was on a conference call in a meeting room and I thought something weird is happening with my face and started to droop. So I walked out of the meeting room and then my boss at the time just looked at me and said, we need to get you in a taxi or an ambulance to the hospital. You're having a stroke.

I was like, how am I going to be having a stroke? Like I'm young. This is like, this can't be happening. So we go to the hospital, got triaged in straight away. And they scanned me and said, there isn't any blockages. We can't really, we don't really know what's happening. So I went back to work the following day. And then from that day onwards for about 30 days, I was having one of these like droopage, like seizures where everything was spinning around me every single day.

So again, this kind of somewhat links to the women's health discussion that we were having earlier. I got passed between so many different people and it was neurologists and it was cardiologists and it was all sorts of different things, psychologists to see what is happening. And nobody could figure out where I was until eventually they said, this is a very, very rare, what they called epigenetic form of migraine.

And it's called hemiplegic migraine. And basically you have it in your genes that you could have the potential to develop this, but it only manifests if you have put your body under a lot of strain. So a lot of cortisol and a lot of adrenaline is going to trigger this. And once you start having them, you're forever.

going to have them. But they started to get so severe that I would wake up in the morning and then this thing would happen. But then from my face, then it went to my hand and then it went to my leg. So there were days when I couldn't really walk. I couldn't really just kind of feed myself or like go to the toilet on my own. So I needed a lot of help from, at the time, my fiance, who's now my husband and father of my child. So I think that he stuck around because at that time he could have gone like,

I don't know what's going on. I'm getting out of here. But a lot of help from my friends, a lot of support from my now husband and also from my employer, to be fair, to just make sure that was supported. But I couldn't work for six months because these things kept going. And the brain fog, the pain, the sort of feeling of the room spinning and then the inability to function meant that at the time they didn't really know if I was going to be able to work again.

So moving around urologists, eventually I came across somebody that said, we need to completely reset your life. You need to go back to no caffeine, no sugar. We need to kind of like clean you up entirely. You need to start doing strength training. You need to get your steps in. We need to get you to speak to somebody to offload. Some of the reasons why this has happened because physical health and mental health are so intertwined.

So I had to do all of those things. It came to the point where I started to get a little bit better, but it was still happening. And what they decided was, okay, we've got two options. One, we continue on this path and we try a medical device, or we put you on this therapy, which the side effects are pretty significant and you could go into manic depression.

So I said, okay, no, I'm going to try the device and continuing with this sort of like clean living. And at the same time, I was having very intensive therapy because why did I feel the need to constantly put my hand up to totally just say yes to absolutely everything? And there was a lot of soul searching to say, well, where is your source of like

self-worth and self-esteem. Why do you need all of this external validation? Where is this coming from? Is it something has to do with upbringing? Something has to do with gender? Something is just so convoluted that I really had to do the work so that if I was to return to the workplace, it wouldn't happen again. So finally, I made it back. So six months off and I returned. And I think it's just, I've been on an eight-year journey of discovery ever since.

And how do you work differently now and live differently? What are the steps that you take? So post-burnout, I had to kind of like reset on everything. So first of all, from a physical health perspective, so making sure that I wasn't abusing sugar and caffeine and alcohol, eating a lot of protein and a lot of vegetables and fiber and exercise, exercise, exercise.

exercise for me is like my outlets to make sure that my brain stays healthy. And then the second piece is I'm throwing myself back into the lion's den here. So I can do all of these good things on the physical health side. But if I don't make sure that I don't address the other pieces, I could go back very, very quickly. So the first thing was I need to learn to set boundaries and say no. And two things happen. I did a graduated return. So the first week I was there for an hour. Second week I

I was there for four hours the third week and I built it up over a course of about two to three months until I went back at full time. And that in itself was a learning experience because how much can you do with a small chunk of time? You can't say yes to everything. You have to be very deliberate as to what you take on and what you say no to. So that was my sort of like coming up to speed and then until we were able to take the little wheels off and I was off on my bike.

So that was one thing, just learning to say no and sitting with a discomfort of saying no and then really sitting with a feeling is like, why is this uncomfortable? Is this uncomfortable because somebody is going to think less of me? And then going once again and saying, why do I need them to think that I'm amazing? I need to tell myself that I'm amazing. I don't need all of these other people.

And then the third thing was just the difference between what we call extrinsic and intrinsic motivation. So extrinsic motivation is when you're motivated by things outside of you. So it could be money. It could be visibility. It could be power. It could be somebody giving you a nice little pat on the head, which was totally my motivation, to actually...

Why am I doing this that makes me happy, that makes me fulfilled, that makes me want to do these things? And doing more of that, finding more the opportunities to really cultivate that intrinsic motivation. Because if you're intrinsically motivated, you don't need as much of the external stuff. So it was a combination of all of those things.

If I'm a leader looking to prevent burnout in my team or even a worker looking to have self-care, what should I be thinking about or doing? As we know now that you may not even recognize that you are experiencing burnout when you're in it. What should people do?

Let me start by talking about how to identify burnout in yourself. So burnout was a condition that was kind of studied and first accepted by the WHO, I think it was something like 50 years ago. And it came from, I think it was a German center of like support workers for the community. They really wanted to give and then they started to experience this like fatigue and quickness to

anger and irritability and the inability to switch off and your brain is constantly on. And there was a doctor as part of that team, and he started to see all of this happening within the employees of this system. And that's when he sort of put together Burnout. So as an individual, if you start to feel like you are not able to rest at night, that your mind is constantly wearing, that even to your loved ones or to your colleagues, you're very quick to anger, you're very kind of cutting and sharp.

And that even though you have a mountain to do, you sit down to do your work and you actually cannot because you can't see the wood for the trees and you almost don't know where to start. Those are real symptoms of burnout. So that's how as an individual, you can watch out for it. But also critically, we all work in teams these days. So it's also the responsibility of looking out for those factors in others as we cooperate really closely. The main thing that I would say to leaders is that

We need to create a culture of openness about mental health and in the workplace. I feel that we took some really positive strides on the lead up and in particular during the pandemic because everybody was really worried about there's so much instability and this is affecting individuals' mental health. But I think we've come on the back of that. And I think two things. One, that I really think that we all have a little bit of post-traumatic stress after the pandemic, that it is just bubbling in there and we haven't addressed it.

And it's also a little bit now like the return to like, we must like productivity, productivity, productivity and percentageism in the workplace and all that kind of stuff. So how do we make sure that mental health continues to be a conversation in the workplace? That we create the safe spaces

where everybody can talk about it so that if you're feeling that yourself, you don't feel like the career opportunities are going to go away or you're going to be looked at differently by your bosses or your colleagues. And also that we feel that we can support each other if we see somebody's going through this.

And your last question, is there a piece of advice that you've always been grateful for? So the piece of advice that I've always been most grateful for, I grew up in the north of Spain in a very small town. I come from a family of entrepreneurs who just cultivated a number of failures and then a couple of successes, thankfully. And my parents always taught me from the beginning, you have to work hard, you have to be kind, and then good things would happen.

That was Paula Belostes-Megersa. Thanks so much to her and thanks so much to you for listening. Paula recently worked with the World Economic Forum on a special white paper, Prescription for Change, Policy Recommendations for Women's Health Research. Learn more about how changes in how we collect data or work with those conducting clinical trials can bring a step change for half the population.

Find a transcript of this episode, as well as transcripts from my colleague's podcast, Radio Davos, at wef.ch slash podcasts. This episode of Meet the Leader was produced and presented by me, with Jerry Johansson and Taz Kelleher as editor, Juan Toran as studio engineer in Davos, and Gareth Nolan driving studio production. That's all for now. I'm Linda Lucina from the World Economic Forum. Have a great day.