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cover of episode PMDD Demystified: Understanding a Severe Mood Disorder Beyond PMS

PMDD Demystified: Understanding a Severe Mood Disorder Beyond PMS

2025/4/17
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Health Discovered

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Dr. Heather Hirsch
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Dr. Neha Bhattach
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Dr. Neha Bhattach: 我是 WebMD 的首席医生编辑,今天我们讨论的是 PMDD,这是一种影响全球数千万女性的疾病,它与 PMS 不同,症状更加严重,会影响日常生活,包括工作、人际关系和自我认知。我们应该更多地了解 PMDD,并寻求有效的治疗方法。 Dr. Heather Hirsch: 我是女性健康领域的专家,专注于围绝经期、PMDD 和更年期等方面。PMS 是正常的生理过程,与月经周期中雌激素和孕激素水平的变化有关。PMDD 则是一种更严重的疾病,症状包括严重的脑雾、易怒、愤怒、敌意、腹胀、水潴留和体重增加等,严重影响生活质量。PMDD 的诊断是临床诊断,需要患者记录和追踪症状,以识别周期性模式。治疗方法包括连续服用避孕药(避免服用安慰剂片),以维持稳定的激素水平;对于不愿服用避孕药的女性,可以在月经前使用绝经后雌激素贴剂来缓解 PMDD 症状;生活方式干预,例如调整饮食、进行温和运动和压力管理,也有助于稳定 PMDD 患者的情绪。 Dr. Neha Bhattach: PMDD 的诊断需要区分其他情绪障碍,例如重度抑郁症。PMDD 的症状具有周期性,随月经周期波动,而重度抑郁症则表现为持续性的低落情绪。PMDD 的风险因素包括既往情绪障碍史、产后或围产期情绪波动等。治疗 PMDD 的方法包括避孕药、激素替代疗法和生活方式干预。女性应该关注自身激素变化,记录症状,并寻求医疗帮助,不要羞于谈论 PMDD。

Deep Dive

Chapters
This chapter defines PMDD and PMS, highlighting the intensity and impact of PMDD on daily life. It explains the hormonal fluctuations that contribute to PMDD symptoms and how these symptoms disrupt relationships and work.
  • PMDD affects 1.6% of the population or 30 million people worldwide.
  • PMDD is a more severe form of PMS, significantly impacting daily life.
  • Estrogen decline and progesterone increase amplify PMDD symptoms.
  • Symptoms include severe brain fog, irritability, anger, hostility, bloating, and water retention.

Shownotes Transcript

Premenstrual dysphoric disorder (PMDD)) affects an estimated 31 million people worldwide, yet remains widely misunderstood. How is it different from premenstrual syndrome (PMS))? Why can it magnify symptoms like irritability, brain fog, and emotional distress—and how does that ripple into work, relationships, and identity? In this episode, we talk to Heather Hirsch, MD, MS, NCMP), author of Unlock Your Menopause Type, about what defines PMDD, how it's diagnosed, how to tell it apart from other mood disorders, and the latest in treatment options, risk factors, and lifestyle changes that can help.

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