#015-What is the best way to detect ketosis?

Ketones and ketosis are everywhere in the news. What are ketone bodies?

Why are they good for us? How do we measure them?
Our guest today is Jim Howard, the CEO of biomarker-based startup

Readout Health. Their product Biosense is the first clinical-grade, handheld

device that measures nutritional ketosis for chronic disease and

longevity/wellness focused consumers. He is a digital health

executive with an MBA from University of Missouri-Saint Louis.

Take away points:

Three Ketone bodies are produced as a by‐product of fat metabolism. When the liver metabolizes free fatty acids, they are transformed into acetyl‐CoA, a molecule used in the production of energy. Depending on the glucose level, acetyl‐CoA can be diverted to produce acetoacetate, the first of three ketone bodies. Acetoacetate can further produce β‐hydroxybutyrate and acetone, by enzymatic degradation or spontaneous decarboxylation respectively.

All three ketone bodies circulate in the bloodstream. Acetone, because of its small size, diffuses into the lung and appears in the exhaled breath. The devices we will be discussing detect levels of acetone from this process.

Deep lung measurement.

Biosense Breath Ketone Monitor -Use the code Lufkin20 for a $20 discount at
https://mybiosense.com/

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Jim Howard MBA: Tools for Monitoring Fasting/Ketosis 38:53 Share

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Jim Howard MBA: Tools for Monitoring Fasting/Ketosis