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cover of episode Dr. Peter Attia: Improve Vitality, Emotional & Physical Health & Lifespan

Dr. Peter Attia: Improve Vitality, Emotional & Physical Health & Lifespan

2023/3/20
logo of podcast Huberman Lab

Huberman Lab

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People
A
Andrew Huberman
是一位专注于神经科学、学习和健康的斯坦福大学教授和播客主持人。
P
Peter Attia
Topics
Andrew Huberman: 本期节目重点讨论健康跨度、活力和长寿,以及心理健康。Peter Attia 医生系统地讲解了全球七大死因,包括心血管疾病、脑血管疾病、癌症、意外死亡、痴呆和绝望之死等,并解释了如何通过行为、营养、补充剂和处方药等方法来预防这些死因,从而延长健康跨度和寿命。他还强调了情绪健康对身心健康和寿命的重要性。 Peter Attia: 需要区分寿命和健康跨度。寿命是简单的二元概念(活着或死了),而健康跨度则更复杂,它包含生理、认知和情绪三个维度。动脉粥样硬化疾病是全球最主要的死因,其预防方法包括控制血压、不吸烟和降低ApoB水平。胆固醇是人体必需的脂质,但过高的胆固醇水平会增加动脉粥样硬化的风险。ApoB水平比LDL-C水平更能预测动脉粥样硬化的风险。降低ApoB水平的方法包括改善胰岛素抵抗和药物治疗(他汀类药物、依折麦布、PCSK9抑制剂)。癌症是全球第二大死因,其风险因素包括遗传因素、吸烟和肥胖。大多数癌症是由获得性突变引起的,而吸烟和肥胖是获得性突变的主要环境驱动因素。阿尔茨海默病是最常见的痴呆症和神经退行性疾病,其主要风险因素是年龄,但可以通过改善睡眠、降低低密度脂蛋白胆固醇和ApoB水平、控制血糖以及进行适当的运动来降低风险。ApoE基因的e4等位基因与阿尔茨海默病风险增加有关,但并非决定性因素。意外死亡的主要原因包括交通事故、跌倒和药物过量。对于老年人来说,意外死亡的主要原因是跌倒。力量训练的四个支柱是离心力量、稳定性、有氧效率和有氧峰值输出。情绪健康对长寿至关重要,它包括与他人建立联系、拥有目标感、调节情绪、体验满足感和成就感等方面。改善情绪健康的关键在于及时修复人际关系中的裂痕,而不是追求完美。

Deep Dive

Chapters
This chapter defines lifespan and healthspan, differentiating between them and introducing the three dimensions of healthspan: physical, cognitive, and emotional. It also discusses the major exit points from life and how to stay on the path to longevity.
  • Lifespan is binary (alive or dead), while healthspan is the period of time free from disability and disease.
  • Healthspan is considered along three dimensions: physical, cognitive, and emotional.
  • Longevity addresses lifespan, physical health (beyond disability and disease), cognitive health, and emotional health.

Shownotes Transcript

In this episode, my guest is Peter Attia, M.D.) He completed his medical and advanced training at Stanford University School of Medicine, Johns Hopkins School of Medicine and the National Institutes of Health (NIH). Dr. Attia is host of the health and medicine podcast, The Drive), and the author of a new book, “Outlive: The Science & Art of Longevity),” which examines disease prevention and healthy aging, including emotional health. He explains the leading causes of death worldwide and how to measure one’s risk of death and mitigate each risk factor. Dr. Attia shares how, in addition to blood-based markers of lipids and hormones, there are behavioral measures and interventions, and key aspects of emotional health (i.e., relationships, emotional stability, purpose, etc.) that fundamentally impact our physical health and longevity, and how to assess and adjust our emotional health. This episode is rich with actionable information related to disease screening and biomarker testing, nutritional, exercise, behavior and prescription-based tools that area useful to all people regardless of age, male or female, and that can significantly improve vitality, health and lifespan.

For the full show notes, visit hubermanlab.com).

Thank you to our sponsors

AG1: https://athleticgreens.com/huberman)

LMNT: https://drinklmnt.com/huberman)  

Momentous: https://www.livemomentous.com/huberman)

Timestamps

(00:00:00) Dr. Peter Attia

(00:03:39) Sponsor: LMNT

(00:07:34) Lifespan vs. Healthspan

(00:10:54) “4 Horseman of Death”, Diseases of Atherosclerosis

(00:14:44) Tool: Hypertension & Stroke, Blood Pressure Testing 

(00:23:14) Preventing Atherosclerosis, Smoking & Vaping, Pollution

(00:28:33) Sponsor: AG1

(00:33:29) Cholesterol, ApoB

(00:42:21) Cholesterol Levels, LDL & ApoB Testing

(00:49:29) ApoB Levels & Atherosclerosis, Causality

(01:01:06) ApoB Reduction, Insulin Resistance, Statins, Ezetimibe, PCSK9 Inhibitors

(01:12:30) Monitoring ApoB

(01:18:30) Reducing Blood Pressure, Exercise & Sleep

(01:20:50) High Blood Pressure & Kidneys

(01:23:11) Alcohol, Sleep & Disease Risk

(01:31:21) Cancer & Cancer Risks: Genetics, Smoking & Obesity

(01:39:47) Cancer Screening & Survival

(01:44:17) Radiation Risks, CT & PET Scans

(01:48:48) Environmental Carcinogens

(01:52:11) Genetic & Whole-Body MRI Screening, Colonoscopy

(01:58:47) Neurodegenerative Diseases, Alzheimer’s Disease, ApoE

(02:08:08) Alzheimer’s Disease & Amyloid

(02:13:58) Interventions for Brain Health, Traumatic Brain Injury (TBI)

(02:21:26) Accidental Death, “Deaths of Despair”, Fentanyl Crisis

(02:31:20) Fall Risk & Stability, 4 Pillars of Strength Training

(02:41:05) Emotional Health

(02:53:45) Mortality & Preserving Relationship Quality

(03:02:20) Relationships vs. Outcomes, Deconstructing Emotions

(03:09:34) Treatment Centers, Emotional Processing & Recovery

(03:16:34) Tool: Inner Monologue & Anger, Redirecting Self-Talk

(03:27:37) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac)

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