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cover of episode PCOS - Polycystic Ovarian Syndrome. Fertility, Weight and ‘Balancing Hormones.’ Uncut with Dr Izzy Smith

PCOS - Polycystic Ovarian Syndrome. Fertility, Weight and ‘Balancing Hormones.’ Uncut with Dr Izzy Smith

2025/5/22
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Life Uncut

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People
B
Brittany
I
Izzy
K
Keeshia
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Keeshia: 我想分享一下我的PCOS经历。我去看皮肤科医生是因为成人痤疮,通过血液检查才发现自己患有PCOS。之前我看了很多医生,但都没有诊断出来。我觉得我的经历很常见,很多人都是在调查其他症状时才发现自己可能患有PCOS。 Izzy: PCOS是指多囊卵巢综合征,但实际上是多卵泡,而非囊肿。PCOS的症状包括排卵功能障碍、雄激素过多等。PCOS可能导致痤疮、体毛增多、脱发、月经不调、不孕、子宫内膜增厚、代谢综合征风险增加等。PCOS与垂体、卵巢和肾上腺的异常沟通有关,症状差异很大。PCOS容易被误解和误诊,因为每个人的症状差异很大。拥有多囊卵巢并不意味着患有多囊卵巢综合征,反之亦然。家庭激素测试或非医疗从业者的血液分析可能存在问题,因为血液测试只是一个时间点的数据。医生需要临床经验来综合判断,全科医生不可能成为所有领域的专家。

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PCOS, or polycystic ovarian syndrome, is a condition affecting 1 in 9 women. It's often misdiagnosed due to varying symptoms and the complexity of hormonal interactions. Misdiagnosis can stem from insufficient investigation, focusing on isolated symptoms rather than the whole picture.
  • PCOS affects 1 in 9 women of reproductive age.
  • Symptoms vary widely, leading to misdiagnosis.
  • Diagnosis requires considering multiple factors beyond ovarian cysts.
  • Medical systems with short appointment times and lack of specialist referrals contribute to misdiagnosis.

Shownotes Transcript

Polycystic ovarian syndrome or PCOS is a condition that affects 1 in 9 women. The symptoms include things like pimples, increased body hair, thinning of the hair on our head, missed periods (and the flow on effects that affect fertility and build up of the endometrium which is a risk factor for endometrial cancer), increased risk of developing metabolic syndrome (insulin resistance, diabetes and cardiovascular syndrome) and increased risk of mental health conditions. PCOS sucks! (You can probably tell who from the team is writing these episode notes). Keeshia was diagnosed with PCOS about 4 years ago so today Keeshia and Britt are joined by the wonderful Dr Izzy Smith!

Dr Izzy Smith is an endocrinologist who has special training in women’s health (PCOS, amenorrhea, menopause transition) thyroid dysfunction, eating disorders and athlete health.

In today’s chat we speak about:

The large variety of symptoms & why it’s often misdiagnosed What’s going on with our hormones  PCOS and fertility Lean PCOS v Overweight PCOS  How insulin resistance develops  Weight management  Cortisol and stress  Treatment options for PCOS What helps and what is marketing BS Endocrine disruptors  Are weight loss medications an appropriate treatment for PCOS?

Find more from Dr Isobel Smith at her website

And her instagram) We referenced an episode about weight loss medications with Johann Hari that you can watch here.)

Izzy also mentioned The Eco Well) and the endocrine society website )

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