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cover of episode Lost Women of Science Conversations: Breaking Through

Lost Women of Science Conversations: Breaking Through

2025/1/9
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Lost Women of Science
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People
D
Deborah Unger
K
Katalin Karikó
K
Katie Hafner
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Deborah Unger: Katalin Karikó 的研究在她的职业生涯中几乎被完全忽视，直到她获得了诺贝尔奖，才被世人所知。她的科学成就使得在创纪录的时间内研制出COVID-19疫苗成为可能，这源于她毕生致力于一项当时不被看好的研究。 Katie Hafner: 与 Katalin Karikó 的谈话让我感到鼓舞，她是一位从未真正被遗忘的科学家，她的职业生涯充满了挑战和坚持。她面临着冷漠、怀疑和直接否定，但她从未放弃对信使RNA的信念。她的故事也体现了女性科学家在科学界所面临的挑战和困境。 Katalin Karikó: 我从小就对科学充满好奇心，并在学习过程中不断克服困难，最终在信使RNA研究领域取得了突破性进展。我的职业生涯充满了挑战和挫折，但我从未放弃对信使RNA的信念，并始终坚持不懈地进行研究。我将那些试图让我生活艰难的人视为激励我前进的动力。在与 Drew Weissman 的合作中，我们发现了修饰后的信使RNA不会引起炎症反应，这为开发安全的信使RNA疗法铺平了道路。虽然我的研究成果最终在COVID-19疫苗的研发中发挥了关键作用，但我认为一线医护人员才是真正的英雄。帮助他人比获得任何奖项都更重要。写这本书是为了向外界展示科学研究的兴奋和挑战，以及看似不成功的背后所付出的努力。

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Dr. Katalin Karikó, a Hungarian-born biochemist, dedicated her life’s work to messenger RNA, which she always believed had the potential to change the world. After decades of being ignored, she persisted with the research that eventually revolutionized the field of medicine and enabled the development of lifesaving vaccines in record time during the COVID-19 pandemic. Dr. Karikó tells her story in her memoir, Breaking Through: My Life In Science, sharing her journey from young researcher in Hungary to Nobel Prize-winning biochemist.

In this conversation, she reflects on the challenges and breakthroughs that defined her career, her resilience, and the scientific curiosity that fueled her passion for mRNA research

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