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cover of episode How does antivenin work?

How does antivenin work?

2025/1/15
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Moment of Um

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Emma Gerstenzang
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Willie McBeans
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Emma Gerstenzang:蛇毒进入血液循环系统后,抗蛇毒血清作为一种结合剂,如同锁和钥匙般与蛇毒结合。它不会杀死蛇毒,而是阻止蛇毒攻击器官和造成进一步伤害。蛇毒仍然存在于体内,但由于与抗蛇毒血清结合,它无法继续发挥毒性作用,直到最终被身体自然排出。这与抗生素杀死细菌的机制不同,因为蛇毒并非活体,无法被杀死。 我的工作是儿科医生,在费城行医。我经常处理各种医疗紧急情况,其中包括蛇咬伤。在处理蛇咬伤时,我们首先要了解蛇毒的毒性以及它对人体的危害。然后,根据蛇的种类和毒液的特性,选择合适的抗蛇毒血清进行治疗。抗蛇毒血清的注射能够迅速中和蛇毒,减轻患者的症状,防止严重并发症的发生。 抗蛇毒血清的研发和生产是一个复杂的过程,需要经过严格的测试和评估,以确保其安全性和有效性。不同种类的蛇毒具有不同的特性,因此需要针对不同种类的蛇毒研发相应的抗蛇毒血清。此外,抗蛇毒血清的剂量也需要根据患者的体重、年龄和病情进行调整。 Willie McBeans:我曾经被响尾蛇咬过,亲身体验了抗蛇毒血清的神奇功效。被咬后,我立刻前往医院,医生为我注射了抗蛇毒血清。几天后,我的症状就消失了。虽然我当时并不了解抗蛇毒血清的工作原理,但我非常庆幸它的存在,它挽救了我的生命。 在这次经历之后,我更加关注医疗知识,特别是关于抗蛇毒血清的知识。我了解到,抗蛇毒血清能够有效地中和蛇毒,防止其对人体的危害。它就像一种紧急清洁剂,能够迅速清除体内的毒素,保护内脏器官免受损害。 虽然大多数蛇类并不具有毒性,但了解抗蛇毒血清的工作原理仍然非常重要。这不仅能够帮助我们更好地应对蛇咬伤等紧急情况,也能够提高我们对医疗知识的认识。

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From the brains behind Brains On, this is the Moment of Um. Moment of Um comes to you from APM Studios. I'm Willie McBeans, the Adventure Queen. Ah.

In my life, I've been on countless incredible expeditions, explorations, and even an exploit or two. I've seen some things that would make you weep with joy, like the sunset over the Himalayas. I've seen other things that would make you hoot and holler with hilarity, like an elk with a tumbleweed caught on his antlers like a toupee made out of sticks. That was a good one. You know, it still gets me.

One time, I was in the desert in Arizona, hiking with some friends. I was so blown away by the gigantic cacti and stunning red rocks around me that I forgot to look where I was putting my feet, and I stepped on the tail of a baby rattlesnake that was basking in the sun on the trail. Yowch! That snake was as startled as I was and did what scared snakes do. It bit me!

It sure did hurt. The hike turned into a hospital trip, a doctor gave me a shot of some anti-venom medicine, and I felt better in a couple days. I never learned how that medicine worked, but I'm sure glad it did. Olivia was wondering about anti-venom too, so let's find out more from an expert. When you think about anti-venom,

First, you want to think about venom. My name is Emma Gerstenzang, and I'm a pediatrician in Philadelphia. Venom is poisonous. So what happens is the venom is circulating through your veins. It's in your blood. And you want to hurry your way to, you know, an emergency room. And they may be able to give you, depending on the kind of snake bite, something called antivenom. And antivenom is something that

binds up with venom. So if you imagine like a lock and a key, the venom is like the key and the antivenom is like the lock. And so if you have venom from your snake bite all in your blood, and then you get antivenom added, right, injected into your blood, or you're given antivenom, and now you have venom and antivenom in your blood, they meet like a lock and a key. The

Anti-venom sticks to the venom so that it can't attack your organs anymore, so that it can't go around and cause all sorts of problems in your body so that you don't get sick. A lot of medicines that we think about, like if you get sick with a virus or you get sick with an infection, if you have an infection from bacteria, you take an antibiotic and that antibiotic actually kills the bacteria.

Anti-venom does not kill venom. It doesn't get rid of the venom from your body in that moment. So the venom is still there, but the difference between venom and bacteria is venom is not alive. So it can't really be killed. And so you have to just wait until the poison is passed out of your body. But in the meantime, it's gets stuck together with the anti-venom so that it can't hurt you while it's still in your body. Um, uh,

So the anti-venom medicine has ingredients that do emergency cleanup in someone's body after they've been bitten by a snake. The anti-venom grabs all the little bits of the poison and holds onto them so they can't go hurting any of your insides. Your body eventually gets rid of the poison. That's pretty incredible.

But you don't have to worry too much about snake venom. There are more than 3,000 snake species in the world, and most of them don't make venom. Plus, snakes really don't want to bite humans. They'd much rather avoid us and mind their own business. Now I'm on to other adventures. I'm thinking, hmm, ocean voyage. No, no, no. Volcano voyage. Mmm, yes. Much more adventurous.

If you like this episode, take a second to subscribe to Moment of Um wherever you listen to podcasts. And if you want more on medicine, check out the Brains On podcast where we have a whole episode all about how ibuprofen stops aches and pains. How nice. Want to see our shows come to life? Head to YouTube where we've got awesome animated Brains On episodes. Search Brains On Universe on YouTube and subscribe.

If you have a question, we'd love to help you answer it. Drop us a line by going to braindance.org slash contact. See you next time and the next day and every weekday. Until then! Have you ever given a flying fish a high five? Life-changing and very wet.