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cover of episode 676 Chris Moxham: Co-Founder & CEO of Transcripta Bio

676 Chris Moxham: Co-Founder & CEO of Transcripta Bio

2025/4/16
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The Kara Goldin Show

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Chris Moxham: 我创立了Transcripta Bio公司,这是一家平台型药物研发公司。我们利用高分辨率转录组数据和前沿AI技术,对现有FDA批准药物和临床试验分子进行筛选,寻找新的治疗方法。我们的目标是缩短药物进入临床的时间,降低成本,并提高药物研发的效率。我们通过建立一个‘实验室循环’,结合传统实验室和AI引擎,快速筛选大量潜在药物,并预测其生物学反应。我们在短短两年内进行了10亿次实验,积累了大量数据,这些数据用于训练机器学习模型,从而预测新的化合物结构是否能调节基因表达,最终达到治疗疾病的目的。我们已经成功地将现有FDA批准药物应用于自闭症等疾病的治疗,取得了显著疗效。未来,我们将继续扩大平台的应用范围,涵盖更多治疗领域,并与更多制药公司合作。 Kara Goldin: 作为主持人,我主要对Chris Moxham及其公司Transcripta Bio的创新药物研发模式进行了深入的访谈和了解。访谈中,我关注了Transcripta Bio的技术创新、商业模式、以及面临的挑战等多个方面。我了解到,Transcripta Bio利用AI和转录组学技术,通过快速筛选和精准预测,显著提高了药物研发的效率和成功率,为患者带来了新的治疗希望。

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On this episode of The Kara Goldin Show, we’re joined by Chris Moxham, CEO of Transcripta Bio, a biotech company revolutionizing drug discovery through the power of AI and transcriptomics. With a unique platform built on a vast perturbation atlas of small molecules, Transcripta is uncovering novel opportunities across a wide range of human diseases—faster and with more precision than traditional methods.In our conversation, Chris shares the story behind Transcripta Bio and how the team is building frontier AI models to predict biological responses from potential drug compounds. We dive into what makes their approach different, why a transcriptome-first strategy matters, and how they're unlocking insights that have the potential to lead to more targeted and effective therapies. Chris also speaks about the mindset required to lead in a rapidly evolving industry, the collaboration between AI and human expertise, and what’s next for the company.If you’re curious about the intersection of science and technology, the future of drug discovery, or the kind of leadership it takes to build something truly transformative, this episode is one you won’t want to miss. Now on The Kara Goldin Show.

 

Are you interested in sponsoring and advertising on The Kara Goldin Show, which is now in the Top 1% of Entrepreneur podcasts in the world? Let me know by contacting me at [email protected]). You can also find me @‌KaraGoldin on all networks.

 

To learn more about Chris Moxham and Transcripta Bio:https://www.transcriptabio.com)https://www.linkedin.com/in/christophermoxham)https://www.instagram.com/transcriptabio)https://www.linkedin.com/company/transcriptabio)

 

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Check out our website to view this episode’s show notes: https://karagoldin.com/podcast/676)