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cover of episode Jia Tolentino on the Ozempic Weight-Loss Craze

Jia Tolentino on the Ozempic Weight-Loss Craze

2023/3/24
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The New Yorker Radio Hour

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Jia Tolentino:Ozempic作为一种GLP-1激动剂,最初用于治疗2型糖尿病和肥胖症。其通过模拟人体内的一种激素来产生饱腹感,从而帮助减肥。然而,由于名人们的广泛使用,Ozempic被误用作减肥工具,引发了公众对其用途的误解。这种现象反映了当代社会对瘦身的不健康追求。Ozempic并非一种可以随意使用的药物,它需要长期使用,并且可能产生严重的副作用,例如呕吐和腹泻。此外,停止使用后体重会反弹,并且需要定期进行血液检查以监测潜在的肾脏、胰腺和胆囊问题。目前缺乏关于非肥胖或2型糖尿病患者使用Ozempic的大规模安全数据。总而言之,Ozempic对某些人来说可能是救命稻草,但对于其他人来说,随意使用是不明智的,其流行也加剧了对真正需要该药的患者的药物获取难度。 David Remnick:访谈围绕Ozempic的用途、副作用、以及其在名流圈中的流行展开。David Remnick主要通过提问引导Jia Tolentino阐述Ozempic的机制、社会影响以及潜在的健康风险,并探讨了公众对该药物的认知偏差以及对真正需要该药的患者的影响。

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Ozempic, a GLP-1 agonist, was initially approved for type 2 diabetes and obesity treatment. It works by mimicking a hormone that promotes satiation, leading to weight loss. The drug has gained popularity due to celebrity usage and its effectiveness in rapid weight reduction.

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The prescription drug Ozempic was designed to help people with Type 2 diabetes manage their disease, and, under the name Wegovy, to treat obesity. But it has been embraced recently as a tool for weight loss, and many celebrities are rumored to use it in order to shed pounds. Known generically as semaglutide, the drug gives users the feeling of satiation—even to the point of uncomfortable fullness. “One doctor I spoke to compared it to a turkey dinner in a pen,” the staff writer Jia Tolentino tells David Remnick. Tolentino recently reported on) the use and misuse of the drug, and what its prominence among celebrities says about our relationship to thinness today. After some years in which body culture seemed to become more accepting, Tolentino fears the drug will wind the clock back to the brutal insistence on thinness of decades past. “Like any technology, it’s very complicated,” she says. “For some people, this drug might save their lives. For others, it does not make sense to be used in any casual way.”