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cover of episode How David Fajgenbaum saved his own life — and thousands of others

How David Fajgenbaum saved his own life — and thousands of others

2025/3/25
logo of podcast WorkLife with Adam Grant

WorkLife with Adam Grant
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David Fajgenbaum: 我是一名医生科学家，通过重新利用药物并亲自测试，挽救了自己的生命，也帮助了数千名其他患者。我患有卡斯特尔曼病，这种疾病会攻击重要器官，我曾多次濒临死亡。在医学院学习期间，我开始在实验室测试不同的药物，最终发现了一种可以挽救我生命的药物。此后，我创立了EveryCure非营利组织，致力于利用人工智能技术寻找更多可以重新利用的药物，帮助更多患有罕见病的患者。我的工作流程包括利用AI平台对所有药物和疾病进行匹配，筛选出潜在的药物再利用机会，然后进行实验室研究或临床试验，最终通过公众宣传将这些药物推广给患者。在这个过程中，我克服了经济激励不足和功能固着等障碍，并始终保持积极乐观的心态。我坚信，通过努力，我们可以找到更多治疗罕见病的方法，帮助更多患者延长生命，过上更有意义的生活。 Adam Grant: 作为一名组织心理学家，我被David Fajgenbaum的经历深深打动。他不仅凭借自身的毅力和智慧战胜了疾病，更重要的是，他将这种精神转化为行动，创立了EveryCure，帮助更多患者。他的故事展现了人类的韧性以及科技在医疗领域的巨大潜力。通过与David的对话，我了解到药物再利用的巨大潜力，以及克服经济激励不足和功能固着等障碍的重要性。同时，我也对EveryCure的工作流程和AI技术的应用产生了浓厚的兴趣。David的经历和EveryCure的工作，为我们提供了新的视角，也为我们带来了希望。

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David Fajgenbaum had his last rites read to him at 25 years old after a brutal struggle with an inflammatory disease that attacks the vital organs. As a medical student with two weeks left to live, he repurposed a drug and tested it on himself—and saved his own life. Now, he’s repeating the same process for many others through his nonprofit, Every Cure, with the mission of unlocking the full potential of existing drugs to treat every disease possible. David and Adam discuss the building blocks of resilience, explore the disincentives that prevent hidden cures from coming to light, and explain how AI is aiding creative discovery to save lives. 

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Host: Adam Grant (Instagram) | LinkedIn) | Website))

Guest: David Fajgenbaum (Instagram) | LinkedIn)) 

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