294. Hyperbaric Oxygen Therapy Benefits & Science
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Thank you for listening to the Boost Your Biology podcast. My name is Lucas Owen. I uncover the most cutting edge health information on the planet, ranging from hormones, nutrition, supplementation, fat loss, biohacking, longevity, wellness, and a whole lot more. Welcome to the Boost Your Biology podcast.

Hello, ladies and gentlemen, and welcome back to the Boost Your Biology podcast. Today, I'm super excited. We'll be diving deep into hyperbaric oxygen therapy. And I have a very special guest joining me on the podcast. We have Daryl Calder. Daryl, welcome to the podcast.

thank you very much lucas it's a pleasure to be here with you awesome so maybe daryl i guess a lot of my audience has probably maybe heard about hyperbaric oxygen therapy hbot in the context of i guess wellness and longevity and and healing but before we get into that i'd love to hear about your story how you became so fascinated with this particular therapy yeah certainly it was certainly a journey

It's taken me on this path to learning lots about hyperbaric oxygen therapy and bringing Chambers into Australia. But it started, I was in the fitness industry for 30 years owning health clubs, multiple health clubs I owned. So I was under quite a fair bit of stress at times. Had been traveling a little bit and through my travels, I picked up Lyme disease and

I was unknowing at the time, so I was 10 years undiagnosed. I had all these symptoms going on for many, many years. I saw multiple doctors, and the typical story with Lyme disease, you end up with a psychiatrist, get put on antidepressants, and it's all in your head. I got to a point where my body was really failing, and so I had to make some dramatic decisions.

Found a functional medicine doctor who clinically diagnosed me with Lyme disease and that was then supported with pathology that was sent over to Germany. I think it was about 24 vials of blood later over to Germany and got it diagnosed.

But once I got the diagnosis in Australia, there's really no treatment for Lyme disease. There's an acute treatment, which is two weeks of antibiotics, isoclone, and then that's it. And so I was left a little bit stranded to find out pathways to heal myself. So I joined forums and started to do research, learned a little bit about hyperbaric, started doing some treatments in Melbourne in a medical grade chamber.

but found they were very expensive, about $350 a session. You couldn't get access to hyperbarics in hospitals, like the Alfred has a hyperbaric chamber, but you can't get access to that unless you've got a certain condition. So I had to go private. But then dealing with the stress of travelling, doing an hour session here, going, doing another treatment, it wasn't helping the recovery process.

So I started searching overseas for treatment and found a clinic in Cyprus and decided to go over there. And I had extensive eight-week treatment protocol where the foundation of that treatment was hyperbaric oxygen therapy. After I recovered, I started referring patients or helping Lyme patients from Australia go over to Cyprus for treatment and then recovering.

As it came about, I ended up moving over to Cyprus, working within that clinic full-time and then ended up running that clinic. So I started working with doctors, hiring doctors and running this hyperbaric facility which then further enhanced my education and knowledge on hyperbarics. I came back to Australia two years ago and wanted a chamber for myself and found they weren't readily available.

So I started exploring ways to bring chambers into Australia and got one for myself and other people wanted one and suddenly it has evolved into a business where I help people heal using hyperbaric oxygen therapy and so they have their own personal chambers. Remarkable, yeah. Now I'd really love to learn more about, I guess because a lot of my audience, they're probably like,

maybe unfamiliar with this term, like what it actually involves. So did you want to sort of break down, Daryl, just explain, like, what is the purpose of a hyperbaric oxygen therapy? What is, how does it actually work?

Okay, so let me go back a little bit further. So there's two types of hyperbaric oxygen therapy. There's a medical grade chamber and then there's what's called mild hyperbaric chamber. So looking at a medical grade chamber, it's in a hospital environment. You're breathing 100% oxygen. To breathe 100% oxygen, you need to be prescribed that by a doctor. So it needs doctor supervision.

It's quite a technical piece of equipment because it's all manually operated. So you've got a technician operating the chamber, you've got a doctor present. Hospitals usually have what they call multi-place chambers. So they're chambers where multiple people can fit in. So then you have a nurse in there, a chamber attendant supervising. So it's quite a complex treatment protocol. And you can understand why it's so expensive. Those multi-place chambers are...

close to a million dollars a unit. And then there's mild hyperbaric oxygen therapy. So that is usually monoplace chambers, which mean one person chamber. You can get multi-place chambers, but they're mostly monoplace chambers. And instead of breathing 100% oxygen, you're breathing between 90% to 97% oxygen. And that oxygen is generated through an oxygen concentrator.

opposed to a medical grade chamber where you're breathing 100% oxygen through bottled gas. And when you're breathing 100% oxygen, there's risks factors associated with that. You can get oxygen toxicity. So you need to have oxygen breaks within that type of protocol. Oxygen toxicity, you can, I'm sorry, opposed to a mild chamber where you don't have a risk of oxygen

oxygen toxicity because you're not breathing 100% oxygen. You still have some nitrogen in the mix. And then it becomes more accessible to the average person, so you don't have to – we can't get oxygen concentration. What might be some of the symptoms for patients who have that oxygen toxicity? So there's confusion, dizziness. So you'll know you'll have it straight away. You'll feel unwell. You'll feel disorientated.

All you need to do to overcome those symptoms is remove your mask and breathe air, ambient air, for five minutes. So in a medical-grade chamber, the protocol is you breathe oxygen for 20 minutes and then you have a five-minute air break. Back on oxygen and then a five-minute air break. So they manage that oxygen toxicity. The other risk factor in the chamber is...

Because you're dealing with 100% oxygen, there's a risk of fire. So you can't have anything with static electricity in the chamber that could generate a spark and cause a fire. So there's some very strict protocols in a medical grade chamber that you have to follow. In a mild chamber, you don't have any of those risk factors because you're not breathing 100% oxygen. The type of chamber you're in is called a flow chamber. So the air is flowing in one end, flowing out the other.

dispersing the nitric the air that you're breathing out and then so you're getting that flow through and so there's no risk of oxygen toxicity or anything like that. Now when you went to Cyprus Daryl were you like undergoing the medical grade or were you doing the mild therapy? Initially I was in the medical grade chamber

And so there's a place for medical grade chambers with certain conditions. So when you've got a deep infection, you need to really have a medical grade chamber. Decompression sickness, you have to get treated in a medical grade chamber. Diabetic wounds, you need to get treated in a medical grade chamber.

The difference is the chamber goes down to a greater depth. So usually between 2 atmospheres to 2.5 atmospheres is what's the treatment depth for a medical grade chamber. Opposed to a mild chamber, the treatment depth is either 1.3 atmospheres, 1.5 atmospheres or 2 atmospheres. So with those different...

Obviously, they're ranked. The scale is like 1.1, 1.2, 1.35, then 1.5. Atmospheric, that's our ATA is the measurement there. Just talk us through in terms of potential applications. I mean, you've mentioned with the medical grade chambers, obviously, they're prescribed for certain conditions.

But with the mild hyperbaric chambers, why might someone consider sort of using those ones? With hyperbarics, the deeper you go, it's not necessarily the better. There's a purpose to going deep, but something like traumatic brain injury or post-stroke recovery, autism is ideally treated at 1.3 atmospheres. So you don't need that depth.

to get the benefit. It's a slow recovery. The aim is to get oxygen into the brain and not to cause too much oxidative stress within the body. Because we've been in a full or hyperbaric, medibaric chamber breathing 100% oxygen. One of the other side effects is oxidative stress. And so it can actually make you worse before you get better. The mild chamber is a gentler process, maybe a little bit slower process.

But it's something you can fit into your day, do every day. And sometimes twice a day, depending on your availability, your willingness to recover. You've got to have a four-hour break in between sessions, but it can be done twice a day. Interesting. So I guess, Daryl, with the differences like

Of course, now my audience is probably wondering, what's the soft shell versus hard shell? Talk us through the differences between those. Within the mild hyperbaric realm, there's two types of chambers, soft shell and hard shell. They're usually all monoplace chambers, which are one-person chambers.

The soft shell chambers are made out of a rubber material and literally soft shell. They're quite collapsible, very maneuverable. You can take them from room to room without too much trouble. They're supported by an internal frame, but they only go to 1.5 atmospheres because of the pressure within the chamber. The fabric won't go beyond 1.5 safely. Yeah.

But then to go to the next level, to go to two atmospheres, you go to what's called a hard shell chamber and they're made out of stainless steel. Everyone's seen the traditional tube type chamber where you sort of slide into that. That is a traditional hard shell chamber. Although I had one where you can actually hop in and sit in it. So it's a lot more comfortable, easy to access for people with disabilities and so on.

But yeah, the general difference is soft shell goes to 1.5, hard shells go to 2 atmospheres.

Awesome. Awesome. So I guess what I'm really curious to hear more about Darrell is like, in regards to I mean, obviously, your initial reason for even exploring this modality, this form of healing was for your own, you know, ailments and also, you know, Lyme disease, which is the great mimicker of many different diseases. Yes. Did you want to sort of explore like, why are people interested in this therapy? Like, what are some of the other potential applications?

So at a fundamental level, so hyperbarics has been around for hundreds of years. So it's not a new therapy. It's becoming of age, particularly in Australia. It's been used quite extensively overseas, but in Australia, it's coming of age. At a fundamental level, it increases oxygen saturation of the body. It helps reduce inflammation. It helps upregulate your immune system. It helps...

upregulate gene expression and helps regenerate or generate stem cells within the body. So there's all those benefits and

at the essence it helps healing. So in a medical grade chamber, people would go into a chamber for wound healing. So diabetic ulcers and things like that. So wounds that won't heal normally. So they put them into a chamber and because of the oxygen saturation, the pressure pushing that oxygen through the extremities of the body, the wounds heal. Now, when you take that on a larger scale, it really doesn't matter whether the wound is on the lower limb or

or in the brain, or in the liver, or in the gut, in the colon, it heals wounds regardless. So, you know, post-exercise recovery, it's healing the body after a workout. If you've got a calf injury, and calf injuries are traditionally hard to treat because the blood flow down to that area is limited. So, you know, it accelerates recovery from wounds.

There's lots of doctors doing research now and research is not done across the medical profession in general. It's reliant on a few doctors that own hyperbaric facilities. So there's a doctor, Paul Hutch in America, and he really focuses on conditions associated with the brain. So his wife's got MS and,

So, you know, he's been treating his wife for many, many years and she is almost symptom free. So autoimmune conditions, you know, he focuses on those. He works a lot with veterans who have experienced post-traumatic stress syndrome, you know, blast injuries. So he does a lot of research and documents trials on that. Scientific studies being done there. There's another guy, Dr. Shea in Australia.

in Europe that he focuses a lot on brain function and cognitive function and also cardiovascular and heart conditions. So he does a lot of research in that area. And he actually pioneered a study. It's called the hypoxia hypoxic paradox.

where you can trick the body into thinking it's suffering a hypoxic event and that stimulates stem cell production. Yeah, so that's a whole nother thing. There's a Scott Shearer in America also, very big into brain health and anti-aging using hyperbarics. So there's lots of research being done, but it's very limited to doctors who own facilities.

Right, right. And in terms of like the different types of, I guess, machines, there's some that have masks and there's some that don't have masks. So do you want to sort of point out the differences there? So in a medical grade chamber, you're breathing 100% oxygen, as we mentioned. And so the mask you got there has a two-way valve. You're breathing in oxygen, breathing out carbon dioxide.

The breathing process is a little bit laboursome because you've got to really concentrate on your breathing. In a mild chamber, you have a couple of options. You have a normal mask that you breathe in and out of through the same vents. You can use a nasal cannula. And I like to use a nasal cannula in my chamber when I'm using a computer so it doesn't obstruct my vision.

And then if you want to go to the next level, you can use what's called a non-rebreather, which is very similar to the medical grade chamber. It has a bag underneath the mask where a reservoir captures the pure oxygen. Carbon dioxide comes out the top valve and you breathe some pure oxygen. So in a mild chamber, you're breathing between 90 to 97% oxygen. And it depends on the mask, the delivery system to the purity of oxygen.

Then if you take the mask off in the chamber, you're breathing what's called ambient air. And so that is around 35%. So at the moment at sea level here where we are now, we're at one atmosphere and we're breathing 21% oxygen. Just because the pressure within the chamber is three to four times greater than at sea

at surface level, the oxygen is denser in the chamber. So at breathing without a mask, breathing ambient air, you're breathing 35% oxygen. With a mask, you're breathing up to 75, sorry, 97% oxygen. And in terms of like the frequency of sessions, because people are probably wondering, is it something you do like once a week? Is it preferentially daily? Is there an initial Herxheimer reaction that can occur in early adopters?

Yeah, so in a mild chamber, you can sort of jump into it a lot quicker. In a medical grade chamber, you have to take it slowly because there's a risk of oxidative stress, which then creates the Herxheimer reaction. Herxheimer reaction is the die off of pathogens or viruses in your system, poisoning your system. So you've got to be very careful and you've got to run a detox program as you do that. In a mild chamber, it's a little bit more gentle.

And so you don't necessarily have that effect. Now, some people, if they've got medical conditions, when you're in a chamber, after the session, you would feel fatigued. And that's a healing process going on. You're going through a healing crisis. If you don't have any medical conditions that you're trying to treat, you're doing it for longevity or general health, then you'll feel a sense of euphoria. You'll have a brain full of oxygen and you'll feel quite energetic. Because what happens is the...

The red blood cells are responsible for carrying oxygen through the body, and they only have a certain amount of capacity to carry oxygen. Once you saturate a red blood cell with oxygen, it can't carry any more. And you measure that through a pulsimeter. With a chamber, once you go into the chamber and under pressure, you change the gas temperature.

chemical laws, I suppose. And that oxygen you're breathing is then liquefied and transported through the body in plasma. So you're totally saturating the body with oxygen. You're not relying on red blood cells anymore to carry oxygen. The oxygen is transported through the body, through the plasma, and it goes to the extremities of the body, goes through the brain blood barrier, goes to, you know,

the extremities where blood flow may not normally travel quite easily. If there's obstruction, there's angiogenesis process going on where it creates pathways around that blockage, but it's not an instant fix. You can't just do one or two sessions. You build on sessions. An average protocol would be 20 to 30 sessions. A line protocol is 80 sessions.

But now I would consider myself in remission from Lyme, but I still continue to have a hyperbaric session daily when I can. Yeah, fascinating. So I guess it depends upon the patient, you know, what they're trying to address. But is there any specific like pre and post protocol that you usually recommend? Like do you encourage patients to avoid eating a big meal before it?

or you haven't really seen much differences um now you're sort of going into biohacking hyper barracks yeah and and there's there's ways of you know accelerating um results and and enhancing results so red light therapy prior to going into a chamber red light therapy

increasing blood flow and then you go into the chamber and so that has a positive effect as well or going from a chamber into an infrared sauna again boosting the effect of it combining it combining ice baths with hyperbarics

You can fast. So if you're used to intermittent fasting and go in the chamber on an empty stomach, enhance benefits again. But you have to be accustomed to intermittent fasting. If you're not accustomed to it and you go in there, your blood sugar levels can drop and there could be issues there. So yes, there are ways of enhancing the benefits of it.

Yeah, the reason I bring that up is because there's a pretty renowned biohacker right now who's talking extensively about the benefits of hyperbaric therapy. And one of the famous quotes that I remember him continuously repeating is, and you've probably heard it as well, it's the presence of oxygen is the absence of disease. Yep, Gary Brecker. Yeah, yep, that's the one. Yeah.

Yeah. And that is true. Yeah. Yeah. And that's a powerful statement, isn't it? Yeah, no, definitely. I think there's like, there's a lot of cool things that they sort of forward thinking and I guess like health educators, health influencers, they're sort of, you know, discussing. But as always, I love to, I love to look at the science. And so like when I did some research myself on HBOT therapy and looking at the research around its impacts on

specifically mitochondrial function. Like that's, that's what really excited me. Cause I'm like, I understand that one of the root causes of aging and one of the root causes of disease truly is like a deterioration of proper mitochondrial function. So it appears that like this particular modality alongside, you know, eating plenty of polyphenol rich foods like blueberries, pomegranates, intermittent fasting, doing exercise, going in the sauna,

They all seem to have this one thing in common, and that is that they all seem to improve mitochondrial biogenesis or mitochondrial function in a sense. Yes, I agree. And in my journey with Lyme disease, I self-diagnosed or came to that same conclusion that my fatigue, fibromyalgia and fatigue and all that chronic fatigue is all caused through mitochondrial dysfunction.

And the hyperbaric has certainly helped me in that way, in that area. Yeah, so in terms of like... Sorry, going back to extension of Gary Brekker, bacteria can't live in an oxygen-rich environment. Fungus can't live in an oxygen-rich environment. Viruses can't live in an oxygen-rich environment. So it's a very over-encompassing protocol

treatment modality. I'd imagine there'd be quite a lot of people that have like mold toxicity as well. Could they benefit from hyperbaric? Yeah, absolutely. Absolutely. Along with all the other, you know, you have to rid yourself of the mold environment. Yes. Some natural,

supplementation and so nothing hyperbaric is not the panacea of all ailments it's a big addition to other supportive treatments yeah it's a big compliment to many other modalities it's like a yeah I mean

What I find pretty fascinating as well is like the application for athletes. I might quickly share a bit of an anecdote. When I went to speak in Dubai, I was talking to an owner of a clinic, an anti-age wellness clinic there. And he mentioned that he had to prepare for his marathon race in like less than six months. So he hadn't done any sort of proper training. He had only six months to prepare for this race and

And I asked him like, you know, what did you do to actually get fit? And he swore by the hyperbaric oxygen therapy to enhance his endurance. And he was doing it like before his runs in the mornings. So he'd jump into the chamber, do a 40, a 50 minute session and then go out and run. And he said he felt unbelievable, like amazing. Yep. Well, in essence, what's happening there is,

And I'm not a doctor or anything like that, but Lance Armstrong, his doping thing where you extract blood, increase the red blood cells, put it back in. Essentially, that's what hyperbarics is doing, enhancing the oxygen saturation and flow into the body. Yeah, I find that pretty fascinating. I want to...

i do want to test that out from a aerobic standpoint because i've done a vo2 max test now about six weeks ago and then obviously once i get my hands on you know your cell region uh the soft shell i'll you know i'll do it every day at least 50 minutes a day and then i might actually retest my vo2 max to see

what impact that's had. Yeah. I would encourage you to sort of monitor a number of markers, get a full blood count and a few other markers and do a pre and post analysis of the treatment. Have you had any clients that have done like pre and post sort of blood work after doing many sessions? Most of the people I deal with are dealing with chronic illness

of many different sorts. And so they can easily measure their results in conjunction with their doctor. They've seen pre and post and improvement, but just the general wellbeing, you can just see the difference in someone after a period of 40 treatment protocol. In Cyprus, I had an American come over and he had two strokes

And I had him walk up the stairs day one, up and down the stairs. It took him quite a while. He struggled. He had to hold on to the banister. His leg was shaking and he was very unsteady. After two weeks, he was walking up and down those stairs without assistance.

And I've got videotape of it. And so I see those results. It's incredible. He was very forgetful. And this is not just a one-off type treatment. It's a one-off example. I've seen hundreds of people deal with that. But when you look at it from a...

If someone goes into a chamber for decompression sickness, which is what everyone knows hyperbarics for, they go in there very, very sick. They've got nitrogen bubbles flowing through their body that are traveling towards their brain that could kill them very quickly. And so two or three sessions in a hyperbaric chamber

they're normalized again. You know, they're functioning, their nervous system's back to normal. The risk of a stroke is gone. So you can see how powerful it is. Is that decompression sickness? Is that when divers go too far down? Is that what you're talking about? Yeah. Yeah. So that's, you know, traditionally what hyperbarics have been used for to treat divers with decompression sickness. So they've gone down too far and haven't, you know,

gone had their stops along the way and come up too fast and so nitrogen bubbles have accumulated into their into their bloodstream and so they get the bends um bends affects people in two ways in the joints which causes a lot of pain and buckles people over in pain that's why it's called the bends or it can travel up the spine towards the brain and affect the neurological system

But they go in, they're very, very sick. And after two or three sessions come out as normal. Unbelievable. What would you say, Daryl, is the future of hyperbaric oxygen therapy? Like what sort of direction would you love to see it go in?

I can see it moving now. Post-COVID, a lot of people ended up with long COVID and people are starting to research themselves on how am I going to get rid of this long COVID? And they keep finding hyperbarics. There's lots of studies being done on hyperbarics to deal with long COVID now. And so they're coming to the conclusion that they want to try hyperbarics and they are finding ways to try it.

And people are buying their own chambers. They're taking into their own hands, their health in their own hands and buying their own chambers. I supply most chambers for people for their own personal use in their homes. So I see that as a trend that's going to keep growing. Yeah.

In Australia, we haven't used it much in sports. In Cyprus, we used to have soccer teams come in there and do post-recovery. And these are professional athletes. And then dealing with their injuries. We haven't seen that in Australia as yet with hyperbarics, but I see that as an area that will grow quickly. There's a big future for it.

It's very exciting. It's very exciting. And I might mention to the audience, obviously those listening in, Daryl does actually, you know, distribute and help to sell some of these chambers. Do you want to sort of talk about your process for actually selecting, like what made you select the ones that you've got now?

As I mentioned, when I came back from working over in Cyprus, I wanted my own personal chamber. And then I was looking around in Australia and I really couldn't find one that I was happy with. So I started to do some research. There's some available in Europe, but Europe is very expensive. We lose 40 cents in the dollar when we exchange with Europe.

So I went to China and selected five different companies. And I went, I physically visited China and went to all these companies and saw how they produced their chambers. And I selected one that I wanted to work with because of the quality of product, their level of service.

And now I've been, you know, I've been the Australian New Zealand distributor for almost 12 months now. And we've got a very good working relationship and it's a very good quality product.

Awesome. Yeah. I'll just for reference for anyone who actually wants to check those out, I'll make sure to leave a link in the podcast show notes for those listening in. If they do want to actually check one out or maybe even purchase one for themselves. I'm super excited to be receiving my one, hopefully in the next week or so provided by Darrell and his team. But otherwise, I guess, was there any other...

key points you wanted to sort of address? Darrell, you've done a great job at explaining more about that. We addressed the fundamental mechanism behind hyperbarics. It's wound healing. So anything that any condition that has inflammation associated with it, there's benefit in there. You know, stroke recovery, autism, traumatic brain injury,

fibromyalgia, long COVID, the list is extensive. And I get a great pleasure out of helping people who haven't had much hope in recovering. Like people with fibromyalgia, they don't have much hope with pharmaceutical medications. But something like this, I see people changing and getting their life back. And it's very satisfying. It's a great area to work in.

Yeah, no, it's incredible. And it's also, you know, exciting for people if they're looking for a different modality, they're looking for something that they can implement.

So, yeah, I think it's exciting for the future. I think there's going to be more content coming out around it. Yeah. One thing that I didn't mention also is the anti-aging factor. And this has been scientifically proven. There's a research paper on this that hyperbaric oxygen therapy increases the length of the telomeres. Oh, wow. So that's literally reversing the aging process.

And Dr. Afet Shea over in Europe has done this study and written a paper on this protocol and results. So, you know, that's a huge thing to have increased your length of your telomeres, essentially reversing the aging process.

That's definitely that aspect there from the telomere lengthening. I'll go into greater detail on my YouTube. I'm planning on doing a YouTube video rundown on the latest science around hyperbaric oxygen therapy. And I think, yeah, telomere lengthening is going to be a component of that sort of discussion, which I think, yeah, my audience is going to be extremely, extremely excited to hear about. So yeah,

Yeah. Otherwise, I guess that pretty much wraps up today's podcast. Daryl, thank you so much for making an appearance. I know you're off to Cyprus yourself pretty soon. So yeah, thanks so much for featuring on the podcast. My pleasure. Thank you very much for having me. I really enjoyed your company. Thank you. Awesome.

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