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#175 - Matt Kaeberlein, Ph.D.: The biology of aging, rapamycin, and other interventions that target the aging process
02:40:39
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2021/9/13
The Peter Attia Drive
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What are the various definitions of aging?
How does disease relate to the biology of aging?
Can targeting diseases extend lifespan more than targeting biological aging?
Rapamycin as a longevity agent: What are the challenges?
Human studies using rapalogs for enhanced immune function
What role does inflammation play in aging-related functional declines and diseases?
Do rapalogs improve the immune response to a vaccine?
What are the roadblocks to studying gero-protective molecules in humans?
Potential benefits of rapamycin for age-related diseases: Periodontal, reproductive function, and more
What is the ideal length and frequency of rapamycin treatment for various indications like inflammation and longevity?
Biomarkers of aging and epigenetic clocks
Could a test calculate biological age?
The Dog Aging Project testing rapamycin in pet dogs
The role of the mTOR complexes
mTor inhibitor called Torin2, mitochondrial disease and other potential pathways
Catalytic inhibitors, sirtuins, and NAD
NAD precursors: help or hype?
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