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#210 - Lp(a) and its impact on heart disease | Benoît Arsenault, Ph.D.

2022/6/13

The Peter Attia Drive

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#210 - Lp(a) and its impact on heart disease | Benoît Arsenault, Ph.D.

The Peter Attia Drive

How did Benoît start studying Lp(a)?

What is the connection between Lp(a) and CVD risk?

What did genome-wide association studies reveal about Lp(a)?

How to clinically test for Lp(a)?

What is the biology of Lp(a)?

How do statins affect LDL-cholesterol and Lp(a)?

What makes Lp(a) more atherogenic than LDL-p?

What role does Lp(a) play in aortic valve disease?

How does the number of Lp(a) particles relate to disease risk?

What are the genetics and inheritance patterns of Lp(a)?

What therapies are proposed to lower Lp(a) and CVD risk?

Why is Lp(a) awareness low among physicians?

What is the variability of disease in high Lp(a) patients?

What diseases are most associated with high Lp(a)?

What is the biology of PCSK9 protein and its inhibition?

How effective are PCSK9 inhibitors in lowering Lp(a)?

What is Peter's and Benoît's approach to managing high Lp(a)?

What are antisense oligonucleotides and their potential in treating Lp(a)?

Shownotes Transcript

#210 - Lp(a) and its impact on heart disease | Benoît Arsenault, Ph.D. 02:07:18 Share

The Peter Attia Drive

How did Benoît start studying Lp(a)?

What is the connection between Lp(a) and CVD risk?

What did genome-wide association studies reveal about Lp(a)?

How to clinically test for Lp(a)?

What is the biology of Lp(a)?

How do statins affect LDL-cholesterol and Lp(a)?

What makes Lp(a) more atherogenic than LDL-p?

What role does Lp(a) play in aortic valve disease?

How does the number of Lp(a) particles relate to disease risk?

What are the genetics and inheritance patterns of Lp(a)?

What therapies are proposed to lower Lp(a) and CVD risk?

Why is Lp(a) awareness low among physicians?

What is the variability of disease in high Lp(a) patients?

What diseases are most associated with high Lp(a)?

What is the biology of PCSK9 protein and its inhibition?

How effective are PCSK9 inhibitors in lowering Lp(a)?

What is Peter's and Benoît's approach to managing high Lp(a)?

What are antisense oligonucleotides and their potential in treating Lp(a)?

Shownotes Transcript

#210 - Lp(a) and its impact on heart disease | Benoît Arsenault, Ph.D.