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#238 – AMA #43: Understanding apoB, LDL-C, Lp(a), and insulin as risk factors for cardiovascular disease
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2023/1/16
The Peter Attia Drive
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What is the racecar analogy for understanding atherosclerotic cardiovascular disease?
How do apoB and LDL-C differ?
What is the relationship between insulin levels, apoB, triglycerides, and ASCVD parameters?
How does hyperinsulinemia contribute to endothelial dysfunction?
Why does Peter use the oral glucose tolerance test (OGTT) with all patients?
Is hyperinsulinemia an independent contributor to ASCVD?
What are the risks of high-fat diets improving metabolic metrics but elevating apoB/LDL-C?
What are the risks of low apoB with higher than normal triglyceride levels?
Why is lowering apoB important for reducing ASCVD risk?
How do high apoB and LDL-C impact ASCVD risk in familial hypercholesterolemia?
Why is early prevention important for ASCVD?
What is Lp(a) and how does it impact ASCVD risk?
How does Lp(a) risk differ among ethnic groups?
Should someone with elevated Lp(a) be more aggressive with apoB lowering strategies?
Why might someone hesitate to take a pharmacologic approach to lower ASCVD risk?
Peter’s take on the 2022 Formula 1 season and thoughts on 2023?
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