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#31 - Navdeep Chandel, Ph.D.: metabolism, mitochondria, and metformin in health and disease

2018/12/3

The Peter Attia Drive

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#31 - Navdeep Chandel, Ph.D.: metabolism, mitochondria, and metformin in health and disease

The Peter Attia Drive

What sparked Nav's interest in mitochondria?

What are reactive oxygen species (ROS)?

Are antioxidants beneficial or detrimental?

How do mitochondria act as signaling organelles?

What is the role of hydrogen peroxide (H2O2)?

What is the significance of mitochondrial DNA?

How do mitochondria influence aging?

What are the effects of metformin on health?

How does metformin interact with the gut microbiome?

What is the role of metformin as a complex I inhibitor?

What are the anticancer benefits of metformin?

Is mitochondrial function essential for tumorigenesis?

Are somatic mutations linked to mitochondrial dysfunction?

What is the role of vitamins and antioxidants?

How does targeting inflammation impact disease?

What are NAD precursors?

What is MitoQ?

What is the impact of metabolite toxicity?

How does cortisol affect healthy aging?

How does Peter handle the 'So what should I eat?' question?

Shownotes Transcript

#31 - Navdeep Chandel, Ph.D.: metabolism, mitochondria, and metformin in health and disease 02:22:24 Share

The Peter Attia Drive

What sparked Nav's interest in mitochondria?

What are reactive oxygen species (ROS)?

Are antioxidants beneficial or detrimental?

How do mitochondria act as signaling organelles?

What is the role of hydrogen peroxide (H2O2)?

What is the significance of mitochondrial DNA?

How do mitochondria influence aging?

What are the effects of metformin on health?

How does metformin interact with the gut microbiome?

What is the role of metformin as a complex I inhibitor?

What are the anticancer benefits of metformin?

Is mitochondrial function essential for tumorigenesis?

Are somatic mutations linked to mitochondrial dysfunction?

What is the role of vitamins and antioxidants?

How does targeting inflammation impact disease?

What are NAD precursors?

What is MitoQ?

What is the impact of metabolite toxicity?

How does cortisol affect healthy aging?

How does Peter handle the 'So what should I eat?' question?

Shownotes Transcript

#31 - Navdeep Chandel, Ph.D.: metabolism, mitochondria, and metformin in health and disease