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cover of episode #46 - Chris Masterjohn, Ph.D.: Navigating the many pathways to health and disease - NAD and sirtuins, methylation, MTHFR and COMT, choline deficiency and NAFLD, TMAO, creatine, and more

#46 - Chris Masterjohn, Ph.D.: Navigating the many pathways to health and disease - NAD and sirtuins, methylation, MTHFR and COMT, choline deficiency and NAFLD, TMAO, creatine, and more

2019/3/25

The Peter Attia Drive

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#46 - Chris Masterjohn, Ph.D.: Navigating the many pathways to health and disease - NAD and sirtuins, methylation, MTHFR and COMT, choline deficiency and NAFLD, TMAO, creatine, and more

The Peter Attia Drive

What led Chris to pursue research over medicine?

What is choline and why is it crucial for liver health?

Exploring the rising prevalence of NAFLD: What are the potential causes?

Should we be concerned about TMAO in our diet?

How do different types of fatty acids affect our health?

Why is VLDL not low in NAFLD patients?

How might machine learning revolutionize medicine?

Understanding NAD: Its role, supplements, and sirtuins

Intravenous NAD: What are its implications?

Is oral NR the best way to increase NAD levels?

What are the risks of taking NAD precursors?

The MTHFR gene: What does it mean for health?

The methylation pathway: Why is it important?

The COMT gene: Its role in methylation

Creatine: Its benefits and role in methylation

Dietary strategies for MTHFR: What should we include?

How to mitigate the negative effects of NAD supplements?

A case study: High homocysteine levels

What level of evidence is needed to take health actions?

Does Chris supplement with NAD precursors? Can it help with rosacea?

Decision making with inconclusive data: How to handle the placebo effect?

What does Chris believe that few others agree with?

How to follow Chris’s work?

Shownotes Transcript

#46 - Chris Masterjohn, Ph.D.: Navigating the many pathways to health and disease - NAD and sirtuins, methylation, MTHFR and COMT, choline deficiency and NAFLD, TMAO, creatine, and more 02:51:59 Share

The Peter Attia Drive

What led Chris to pursue research over medicine?

What is choline and why is it crucial for liver health?

Exploring the rising prevalence of NAFLD: What are the potential causes?

Should we be concerned about TMAO in our diet?

How do different types of fatty acids affect our health?

Why is VLDL not low in NAFLD patients?

How might machine learning revolutionize medicine?

Understanding NAD: Its role, supplements, and sirtuins

Intravenous NAD: What are its implications?

Is oral NR the best way to increase NAD levels?

What are the risks of taking NAD precursors?

The MTHFR gene: What does it mean for health?

The methylation pathway: Why is it important?

The COMT gene: Its role in methylation

Creatine: Its benefits and role in methylation

Dietary strategies for MTHFR: What should we include?

How to mitigate the negative effects of NAD supplements?

A case study: High homocysteine levels

What level of evidence is needed to take health actions?

Does Chris supplement with NAD precursors? Can it help with rosacea?

Decision making with inconclusive data: How to handle the placebo effect?

What does Chris believe that few others agree with?

How to follow Chris’s work?

Shownotes Transcript

#46 - Chris Masterjohn, Ph.D.: Navigating the many pathways to health and disease - NAD and sirtuins, methylation, MTHFR and COMT, choline deficiency and NAFLD, TMAO, creatine, and more